TWiV 969: Carl Zimmer on COVID-19
Carl Zimmer visits the Incubator to record a wide-ranging conversation about COVID-19, including origins, vaccines, public health responses, and impact on society. Host: Vincent Racaniello Guest: Carl Zimmer Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - December 28, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 964: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses Dr. Griffin discusses progress toward poliomyelitis eradication in Afghanistan, reduced risk for Mpox after receipt of 1 or 2 doses of JYNNEOS vaccine compared with risk among unvaccinated persons, reduced airborne transmission of SARS-CoV-2 BA.1 Omicron virus in Syrian hamsters, authorized updated (Bivalent) COVID-19 vaccines for children down to 6 months of age, low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by parental mRNA vaccine or a BA.5-bivalent booster, efficacy of antiviral agents against omicron subvariants BQ.1.1 and XBB, incide...
Source: This Week in Virology - MP3 Edition - December 17, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 959: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses effectiveness of influenza vaccination of pregnant women for prevention of maternal and early infant Influenza-associated hospitalizations in South Africa, a multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes, single and 2-dose vaccinations with modified vaccinia Ankara-Bavarian Nordic induce durable B cell memory responses comparable to replicating smallpox vaccines, whether the risk of still and preterm birth is affected by the timing of symptomatic SARS-CoV-2 infection during pregnancy, medical masks versus N95 respirators for...
Source: This Week in Virology - MP3 Edition - December 3, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 957: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks, changes in population immunity against infection and severe disease from SARS-CoV-2 Omicron variants in the United States, updates on COVID-19–related mortality, impact of community masking on COVID-19, effectiveness of the COVID-19 vaccines against hospitalization with Omicron sub-lineages BA.4 and BA.5 in England, cardiovascular outcomes after Tixagevimab and Cilgavimab use for pre-exposure prophylaxis against COVID-19, how Paxlovid is associated with decreased hospit...
Source: This Week in Virology - MP3 Edition - November 26, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 955: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the four things to know about RSV, the burden of respiratory syncytial virus in healthy term-born infants in Europe, the diagnostic accuracy of rapid diagnostic tests for Ebola virus disease, evaluating the accuracy of self-collected swabs for the diagnosis of monkeypox, tecovirimat is effective against human monkeypox virus in vitro at nanomolar concentrations, acute and postacute sequelae associated with SARS-CoV-2 reinfection, clinical course of SARS-CoV-2 infection and recovery in lung transplant recipients, effectiveness of a third BNT162b2 mRNA COVID-19 vaccina...
Source: This Week in Virology - MP3 Edition - November 19, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 952: Jake Scott put the ID in COVID-19
Infectious Disease physician Jake Scott joins TWiV to provide a west coast clinical perspective on the evolution of the COVID-19 pandemic with respect to the impact of vaccines, antivirals, variants of concern and mortality. Hosts: Vincent Racaniello, Alan Dove, Rich Condit,  and Kathy Spindler Guest: Jake Scott Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Omicron variant reproduction ex vivo (Nature) Clinical outcomes with Omicron (Nat Med) Low neutralizing antibodies induced by bivalent booster (NEJM) Antibody responses to bivalent booster (bioRxiV...
Source: This Week in Virology - MP3 Edition - November 6, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 952: Jake Scott put the ID in COVID-19
Infectious Disease physician Jake Scott joins TWiV to provide a west coast clinical perspective on the evolution of the COVID-19 pandemic with respect to the impact of vaccines, antivirals, variants of concern and mortality. Hosts: Vincent Racaniello, Alan Dove, Rich Condit,  and Kathy Spindler Guest: Jake Scott Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV Omicron variant reproduction ex vivo (Nature) Clinical outcomes with Omicron (Nat Med) Low neutralizing antibodies i...
Source: This Week in Virology - MP3 Edition - November 6, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 951: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses Influenza incidence and vaccine effectiveness during the southern hemisphere influenza season in Chile, Nirsevimab for prevention of RSV infection in healthy late-preterm and term infants, severe Monkeypox in hospitalized patients, reinfections with different SARS-CoV-2 Omicron subvariants, impact of community masking on COVID-19 in Bangladesh, unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses, antibody responses to Omicron BA.4/BA.5 bivalent mRNA vaccine booster shot, immunogenicity of bivalent mRNA vaccine boosters, lo...
Source: This Week in Virology - MP3 Edition - November 5, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 949: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses progress toward poliomyelitis eradication in Pakistan, polio by the numbers , influenza and COVID-19 vaccination coverage among health care personnel, phase 1/2a safety and immunogenicity of an adenovirus 26 vector RSV vaccine encoding prefusion F in adults 18–50 years and RSV seropositive children 12–24 months, receipt of first and second doses of JYNNEOS vaccine for prevention of Monkeypox, distinguishing SARS-CoV-2 persistence and reinfection, Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages, association between regular physical activity a...
Source: This Week in Virology - MP3 Edition - October 29, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 947: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the prediction of upcoming global infection burden of influenza seasons after relaxation of public health and social measures during the COVID-19 pandemic, severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters, and how successful immunomodulators for treatment of COVID-19 have opened the pathway for comparative trials. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt at Vaccinated.US Prediction of upcoming global infection burden...
Source: This Week in Virology - MP3 Edition - October 22, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 945: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses a healthcare-associated infection with Monkeypox virus, air and surface sampling for monkeypox virus in a UK hospital, misrepresentation and nonadherence regarding COVID19 public health measures, tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine, clinical, virologic, and immunologic evaluation of symptomatic rebound following Nirmatrelvir/Ritonavir treatment, early outpatient treatment with Eemdesivir in patients at high risk for severe COVID-19, Molnupiravir plus usual care versus usual care alone as early treatme...
Source: This Week in Virology - MP3 Edition - October 15, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Paroxetine vs Quetiapine and Hypercapnia, SARS-CoV-2 Vaccination and COVID-19 Outcomes, USPSTF Recommendation on Anxiety in Children and Adolescents, and more
Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the October 11, 2022, issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - October 11, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 943: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses high points of the multi-national monkeypox outbreaks, monkeypox virus genome mutations, possible occupational infection of healthcare workers with monkeypox virus, rates of monkeypox cases by vaccination status, protection of SARS-CoV-2 infection against reinfection, Paxlovid significantly reduces COVID-19 hospitalizations and deaths, and rebound in COVID19 with and without Paxlovid treatment. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position with Amy Rosenfeld (pdf) Support M...
Source: This Week in Virology - MP3 Edition - October 8, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 942: Omicron boosters with Paul Offit
Paul Offit returns to TWiV for a discussion of SARS-CoV-2 bivalent boosters containing ancestral and Omicron spike mRNAs, including their composition, why they are being recommended by CDC, and who would benefit the most from them. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit,  Kathy Spindler, and Brianne Barker Guest: Paul Offit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) CDC oversells bivalent booster (Wall St Journal) FDA authorizes biva...
Source: This Week in Virology - MP3 Edition - October 2, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 941: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses increased acute respiratory illnesses among children and adolescents, estimates of monkeypox incubation period, generation time, and reproduction number, rapid increase in suspected SARS-CoV-2 reinfections, interim infection prevention and control recommendations for healthcare personnel during COVID-19, SARS-CoV-2 secondary attack rates in vaccinated and unvaccinated household contacts during replacement of delta with omicron variant, breakthrough infection by SARS-CoV-2 delta and omicron variants elicited immune response comparable to mRNA booster vaccination, inter...
Source: This Week in Virology - MP3 Edition - October 1, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts