Coronapod: How to define rare COVID vaccine side effects
From a sore arm to anaphylaxis, a wide range of adverse events have been reported after people have received a COVID-19 vaccine. And yet it is unclear how many of these events are actually caused by the vaccine. In the vast majority of cases, reactions are mild and can be explained by the body's own immune response. But monitoring systems designed to track adverse events are catching much rarer but more serious events. Now scientists need to work out if they are causally liked to the vaccine, or are just statistical anomalies - and that is not an easy task.News: Why is it so hard to investigate the rare side effects o...
Source: Nature Podcast - April 2, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: the Oxford-AstraZeneca COVID vaccine - what you need to know
Since the beginning of the pandemic the Oxford-AstraZeneca vaccine has been plagued by confusion and controversy. The vaccine has been authorised in over 100 countries, tens of millions of doses have been administered, and it has been demonstrated to be safe and effective. However, over the past few weeks the vaccine has again been in the headlines.In this episode of Coronapod, we discuss all of these controversies and ask how they may the reputation of the vaccine, and what that could mean for roll-outs moving forward.News: Latest results put Oxford–AstraZeneca COVID vaccine back on trackNews: What scientists do and don...
Source: Nature Podcast - March 26, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronavirus second wave - vaccination roll out changes, uncertainty about long covid
In the UK, phase 2 of our coronavirus vaccination strategy may be delayed by supply problems, at the same time many GPs, who carried out the majority of the first vaccination phases, are declining to take on the addition burden and are trying to return to normal clinical work. In this podcast, Duncan Jarvies, multimedia editor for The BMJ, talks to the full panel; Partha Kar, consultant in diabetes and endocrinology in Portsmouth, Matt Morgan, a consultant in a intensive care medicine in Cardiff, Helen Salisbury, GP in Oxfordshire, and Nisreen Alwan, public health consultant in Southampton. (Source: The BMJ Podcast)
Source: The BMJ Podcast - March 25, 2021 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Coronapod: Why COVID antibody treatments may not be the answer
In the early days of the pandemic, researchers raced to identify the most potent antibodies produced by the immune system in response to SAR-COV-2 infection and produce them in bulk. The resulting ‘monoclonal antibodies’ have since been tested in a variety of settings as treatments for COVID-19.But despite promising clinical trial results and several therapies having already been approved, antibody therapies have not yet played a large role in the fight against COVID-19. In this episode of Coronapod, we ask why.News: COVID antibody treatments show promise for preventing severe diseaseNews: Antibody therapi...
Source: Nature Podcast - March 19, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: COVID and pregnancy - what do we know?
Since the beginning of the pandemic, there have been many open questions about how COVID-19 could impact pregnant people and their babies – confounded by a lack of data.But now, studies are finally starting to provide some answers. While it does seem that pregnancy is associated with an increased risk of hospitalisation, babies appear to be spared from severe illness in most cases.In this week’s Coronapod we talk about these findings, and the questions that remain – including whether vaccines are safe to give to pregnant people.News: Pregnancy and COVID: what the data say See acast.com/privacy for privacy and opt-out...
Source: Nature Podcast - March 12, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Stephen Thomas - Behind the scenes in the Pfizer vaccine trial
Never has the spotlight been as strong on a clinical trial as that on the Pfizer BioNTech vaccine, the first approved for covid-19. In this interview, Joanne Silberner spoke to its lead principal investigator, Stephen Thomas chief of infectious diseases at SUNY Upstate Medical University, New York, became the lead principal investigator for one of the most closely watched clinical trials in history. They discuss the moment the positive results came through, what will happen to the people who are still enrolled in the trial, but got a placebo dose, and why the trial was designed in the way it was. www.bmj.com/coronaviru...
Source: The BMJ Podcast - March 8, 2021 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Coronapod: Google-backed database could help answer big COVID questions
A repository with millions of data points will track immunity and variant spread.To answer the big questions in the pandemic, researchers need access to data. But while a wealth has been collected, much of it isn’t collated or accessible to the people who need it.This week sees the launch of Global.health, a database that aims to collate an enormous amount of anonymized information about individual COVID-19 cases.On this week’s Coronapod we discuss how this database could help answer the biggest questions facing scientists right now, from variants to vaccines – could data change the game?News: Massive Google-funded C...
Source: Nature Podcast - February 26, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

The BMJ Interview - Jeremy Farrar; sharing the vaccine is enlightened self interest
Jeremy Farrar, is director of the Wellcome Trust, as well as advisor to the government on SAGE. Trained as a medic and with a PhD in neuro-immunology, he was a professor of Tropical Medicine and Global health at the University of Oxford. In this podcast, he tells us why he thinks that vaccine nationalism is a very short-termist response the pandemic, and why he's bullish about new variants of the SARS-CoV-2 virus. www.bmj.com/coronavirus (Source: The BMJ Podcast)
Source: The BMJ Podcast - February 19, 2021 Category: General Medicine Authors: BMJ Group Source Type: podcasts

All your COVID-19 vaccine questions answered, and a new theory on forming rocky planets
Science Staff Writer Jon Cohen joins host Sarah Crespi to take on some of big questions about the COVID-19 vaccines, such as: Do they stop transmission? Will we need boosters? When will life get back to “normal.” Sarah also talks with Anders Johansen, professor of planetary sciences and planet formation at the University of Copenhagen, about his Science Advances paper on a new theory for the formation of rocky planets in our Solar System. Instead of emerging out of ever-larger collisions of protoplanets, the new idea is that terrestrial planets like Earth and Mars formed from the buildup of many small pebbles. This w...
Source: Science Magazine Podcast - February 18, 2021 Category: Science Authors: Science Magazine Source Type: podcasts

Wellbeing special - A post vaccination mindfullness moment
The observation period, after receiving a covid-19 vaccination may be the only 15 minutes someone in the NHS might get all day. In this podcast, we're joined again by Chris Bu, psychiatry trainee who has previously spoken to us about how Burmese Buddhism helped him in his training. He takes us through a guided mindfullness meditation, tailored to that post-vaccination period, to help you make the most of your observation time. www.bmj.com/wellbeing (Source: The BMJ Podcast)
Source: The BMJ Podcast - February 12, 2021 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Coronapod: Is mixing COVID vaccines a good idea?
The science behind how and when to give vaccines doses.As vaccines are rolled out, massive logistical challenges are leading scientists and policymakers to consider alternative dosing strategies.But what does the science say? In this week’s episode of Coronapod, we discuss mixing and matching vaccines and lengthening the time between doses. Approaches like these could ease logistical concerns, but we ask what's known about their impact on vaccine efficacy – what is the science behind the decisions, and could they actually boost immune responses?News: Could mixing COVID vaccines boost immune response?  See aca...
Source: Nature Podcast - February 12, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: Variants – what you need to know
Researchers are scrambling to understand the biology of new coronavirus variants and the impact they might have on vaccine efficacy.Around the world, concern is growing about the impact that new, faster-spreading variants of the SARS-CoV-2 virus will have on the pandemic.In this episode of Coronapod, we discuss what these variants are, and the best way to respond to them, in the face of increasing evidence that some can evade the immunity produced by vaccination or previous infection.News: ‘A bloody mess’: Confusion reigns over naming of new COVID variantsNews: Fast-spreading COVID variant can elude immune responses...
Source: Nature Podcast - February 5, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronavirus second wave - The NHS one year on
The "public health emergency of international concern" was issued by the WHO a year and a lifetime ago. As the UK ramps up testing for the South African virus variant, and is full steam ahead on vaccination, we look back at what we've learned in that time. In this podcast, Fiona Godlee, editor in chief of The BMJ, talks to; Partha Kar, consultant in diabetes and endocrinology in Portsmouth, Matt Morgan, a consultant in a intensive care medicine in Cardiff, and Helen Salisbury, GP in Oxfordshire. They talk about working in the NHS at the moment, the utility of international comparisons, and their remaining questions about...
Source: The BMJ Podcast - February 4, 2021 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Coronavirus second wave - 100,000 deaths
Recorded on the 26th January 2021 The UK has become, officially, the worst performing country in terms of Covid-19 deaths, per head of population - and the number of people in hospital is still higher than at any point in the pandemic. In this podcast, Fiona Godlee, editor in chief of The BMJ, talks to; Partha Kar, consultant in diabetes and endocrinology in Portsmouth, Matt Morgan, a consultant in a intensive care medicine in Cardiff, and Helen Salisbury, GP in Oxfordshire. They talk about working in the NHS at the moment, and the challenges in things like oxygen and vaccine supplies. How the pandemic has exposed a gap...
Source: The BMJ Podcast - January 27, 2021 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Coronavirus second wave - The view from the front line
In the UK, over 37,000 people are in hospital with covid-19, and the NHS comes closer than ever to being overwhelmed - though 4 million people have received their first dose of the vaccine, we are warned that things will get worse before they get better. In this podcast, Fiona Godlee, editor in chief of The BMJ, talks to; Partha Kar, consultant in diabetes and endocrinology in Portsmouth, Matt Morgan, a consultant in a intensive care medicine in Cardiff, Helen Salisbury, GP in Oxfordshire, and Nisreen Alwan, public health consultant in Southampton, about the pressure on hospitals, why GPs are questioning the need for max ...
Source: The BMJ Podcast - January 20, 2021 Category: General Medicine Authors: BMJ Group Source Type: podcasts