TWiV 1038: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses modeling poliovirus transmission and responses in New York State, FDA approves first vaccine for pregnant individuals to prevent RSV in infants, prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices, Nirmatrelvir resistance – de novo E166V/L50V mutations in an immunocompromised patient treated with prolonged nirmatrelvir/ritonavir monotherapy leading to clinical and virological treatment failure, incidence of new-onset hypertension post–COVID-19: comparison with influenza, and post-acute sequel...
Source: This Week in Virology - MP3 Edition - August 26, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1037: Antibodies, the good (CoV), the bad (Ad), the beautiful
TWiV reviews evidence that symptomatic adenovirus infection leads to thrombocytopenia, thrombosis, and production of anti-platelet factor 4 antibodies similar to the rare disorder seen after immunization with adenoviral vectored COVID-19 vaccines, and a monoclonal antibody isolated from a SARS survivor, following vaccination with a SARS-CoV-2 spike mRNA vaccine, that neutralizes a broad collection of ACE2-binding sarbecoviruses. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Link...
Source: This Week in Virology - MP3 Edition - August 20, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1036: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses Florida local transmission of dengue cases reported in Broward and Miami-Dade counties, infants admitted to US intensive care units for RSV infection during the 2022 seasonal peak, long-term risk of death and readmission after hospital admission with COVID-19 among older adults, safety profile and clinical and virological outcomes of Nirmatrelvir-Ritonavir treatment in patients with advanced chronic kidney disease and COVID-19, Fluvoxamine vs placebo for outpatients with symptomatic COVID-19, the effect of corticosteroids, antibiotics, and anticoagulants on the developme...
Source: This Week in Virology - MP3 Edition - August 19, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1035: Poxvirus wars, warp speed COVID-19 vaccine rollout
TWiV dissects a study of COVID-19 vaccination which shows that the timing of initial rollout affects disease outcomes more substantially than final coverage or degree of socioeconomic disparity, and discovery of a novel cellular defense comprising a nuclease that is activated by poxvirus infection and cleaves a specific tRNA molecule to inhibit protein synthesis. Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant ...
Source: This Week in Virology - MP3 Edition - August 13, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1034: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the immunogenicity, safety, and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate, association between nose picking and SARS-CoV-2 incidence, a cohort study in hospital health care workers; effect of COVID-19 vaccination and booster on maternal-fetal outcomes, dynamics of inflammatory responses after SARS-CoV-2 infection by vaccination status in the USA, does monoclonal antibody treatment for COVID-19 impact short and long- term outcomes in a large generalizable population, persistent endothelial dysfunction in post-...
Source: This Week in Virology - MP3 Edition - August 12, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1030: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the use of RSV vaccines in older adults: recommendations of the advisory committee on immunization practices, case report of leprosy in Central Florida, blood group A enhances SARS-CoV-2 infection, predicting COVID-19 incidence using wastewater surveillance data, a common allele of HLA associated with asymptomatic SARS-CoV-2 infection, prevalence of low-frequency, antiviral resistance variants in SARS-CoV-2 isolates in Ontario, Canada, viral resistance analyses from the Remdesivir phase 3 adaptive COVID-19 treatment trial-1, impact of Molnupiravir treatment on patient-r...
Source: This Week in Virology - MP3 Edition - July 29, 2023 Category: Virology Authors: VIncent Racaniello Source Type: podcasts
TWiV 1027: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the transmission of SARS-CoV-2 in free-ranging white-tailed deer in the United States, Omicron subvariant BA.5 efficiently infects lung cells, COVID-19 scent dog research highlights and synthesis during the pandemic of December 2019, T-Cell Immunity against SARS-CoV-2 measured by an interferon-γ release assay is strongly associated with patient outcomes in vaccinated persons hospitalized with Delta or Omicron variants, a common allele of HLA is associated with asymptomatic SARS-CoV-2 infection, and the immunology of long COVID. Subscribe (free): Apple Podcasts, Googl...
Source: This Week in Virology - MP3 Edition - July 22, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1026: Debunking RFK Jr. ’s vaccine funk with Dan Wilson
Dan Wilson returns to TWiV to debunk vaccine misinformation by RFK Jr. during his recent appearance on the Joe Rogan Experience. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Dan Wilson Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Joe Rogan’s worst misinformation yet, with RFK Jr. (YouTube) Every first vaccine has been tested in placebo-controlled trials before going to market. Polio Measles HPV COVID-19 HepB Haemophilus influenzae B Pertussis Diphtheria Tetanu...
Source: This Week in Virology - MP3 Edition - July 16, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1023: Covering science with Katherine Wu
Katherine joins TWiV to discuss her career in science writing, from not liking science at all, to a PhD in microbiology and immunology, and writing for Nova, the NY Times, and The Atlantic, and how the COVID-19 pandemic has impacted her craft. Host: Vincent Racaniello, Kathy Spindler, and Brianne Barker Guest: Katherine Wu Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server All Katherine’s articles at The Atlantic Vaccines still blocking severe disease (The Atlantic) Calling Omicron mild is wishful thinking (The Atlantic) Ta...
Source: This Week in Virology - MP3 Edition - July 9, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1022: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses autochthonous leprosy in the United States, a systematic review to identify novel clinical characteristics of Mpox virus infection and therapeutic and preventive strategies to combat the virus, two-year duration of immunity of inactivated poliovirus vaccine, evaluation of novel oral polio vaccine type 2 SIA impact in a large outbreak of circulating vaccine-derived poliovirus in Nigeria, performance of rapid antigen tests to detect symptomatic and asymptomatic SARS-CoV-2 Infection, effectiveness of the COVID-19 bivalent vaccine, oral Nirmatrelvir and Ritonavir for COVID-1...
Source: This Week in Virology - MP3 Edition - July 8, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1020: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses guidance on measles during the summer travel season, the Infectious Diseases Society of America guidelines on the diagnosis of COVID-19: antigen testing, SARS-CoV-2 variants and age-dependent infection rates among household and nonhousehold contacts, effect of COVID-19 vaccination on household transmission of SARS-COV-2 in the Omicron era, incidence of myopericarditis after mRNA COVID-19 vaccination, intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and Omicron BA.2 variant in Hong Kong, safety, immunogenicity and protection of heterol...
Source: This Week in Virology - MP3 Edition - July 1, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1018: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the CDC vaccine advisory group recommending the newly approved RSV vaccines, association of culturable-virus detection and household transmission of SARS-CoV-2, prevention of COVID-19 following a single intramuscular administration of Adintrevimab, real-world effectiveness of Nirmatrelvir/Ritonavir on COVID-19, and COVID-19 convalescent plasma outpatient therapy to prevent outpatient hospitalization. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode CDC vaccine advisory group recommends RSV vaccines Ass...
Source: This Week in Virology - MP3 Edition - June 24, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1016: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses surveillance to track progress toward poliomyelitis eradication, genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3, evaluation of Oseltamivir used to prevent hospitalization in outpatients with Influenza, viral emissions into the air and environment after SARS-CoV-2 human challenge, has COVID-19 threatened routine childhood vaccination, successful treatment of persistent symptomatic COVID-19 infection with extended duration Nirmatrelvir/Ritonavir, anemia as a risk factor for disease progression in patients admitted for COVID-19, impact of...
Source: This Week in Virology - MP3 Edition - June 17, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1014: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses estimates of SARS-CoV-2 seroprevalence and incidence of primary SARS-CoV-2 infections among blood donors, by COVID-19 vaccination status, smart thermometer–based participatory surveillance to discern the role of children in household viral transmission during the COVID-19 pandemic, COVID-19 vaccine mandates, changing severity and epidemiology of adults hospitalized with COVID-19 in the United States after introduction of COVID-19 vaccines, effectiveness of COVID-19 treatment with Nirmatrelvir–Ritonavir or Molnupiravir among U.S. veterans, national trends in anticoagu...
Source: This Week in Virology - MP3 Edition - June 10, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1010: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the CDC HIV surveillance report, FDA voted in favor of approving the Abrysvo vaccine, canine olfactory detection of SARS-CoV-2-infected humans, safety of the BNT162b2 COVID-19 vaccine in children aged 5 to 17 years, and statement on the antigen composition of COVID-19 vaccines. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode HIV surveillance report (CDC) FDA voted in favor of approving Abrysvo vaccine (Pfizer) Canine olfactory detection of SARS-CoV-2-infected humans (Annals of Epidemiology) Safety o...
Source: This Week in Virology - MP3 Edition - May 27, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
