Reducing “COVID-19 Misinformation” While Preserving Free Speech
Misinformation about COVID-19 (such as around vaccines, masks, and ineffective drugs) has circulated widely during the pandemic, and much of this misinformation is protected by the Free Speech Clause of the First Amendment. Professor of Surgery and Perioperative Care and Professor of Law William M. Sage, MD, JD, from the University of Texas at Austin, is interviewed in this JAMA podcast. Related Content: Reducing “COVID-19 Misinformation” While Preserving Free Speech (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - April 19, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 890: Looking into a booster crystal ball
This episode of TWiV is focused on COVID-19 vaccines and antibodies: who should get boosters, whether a variant matched mRNA vaccine is superior to a historical vaccine, and how the interval between vaccination and infection influences the quality of the antibody response. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode What next for COVID-19 boosters? (NEJM) Boosting with historical or variant mRNA vaccines (Cell) Vaccination-infection interval determines antibody breadth (Ce...
Source: This Week in Virology - MP3 Edition - April 17, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 889: COVID-19 clinical update #110 with Dr. Daniel Griffin
In COVID-19 clinical update #110, Dr. Griffin covers hospital admissions during variant outbreaks, viral load in vaccinated and unvaccinated individuals, predictive capacity of symptoms in children, comparison of antigen tests, incidence of myocarditis after vaccination, steroids during replication phase, Paxlovid efficacy and safety, fluvoxamine, sabizabutin, colchicine, and prevalence of infection in Africa. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Hospital admissions during Omicron and Delta variant outbreaks (Lancet) Viral load in unvaccinat...
Source: This Week in Virology - MP3 Edition - April 16, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 888: Molnupiravir with Richard Plemper
Richard joins TWiV to discuss the SARS-CoV-2 antiviral drug Molnupiravir , including how it was discovered, its mechanism of action, whether it is a mutagen for cells, and the future of drugs for treatment of COVID-19. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Guest: Richard Plemper Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Richard on TWiV 636 Molnupiravir in ferrets (Nat Micro) Oral prodrug of Remdesivir in ferrets (Nat Commun) Letters read on TWiV 888 Timestamps by Jolene. Thanks! Weekly Picks Brianne – BioRender Poster Builder A...
Source: This Week in Virology - MP3 Edition - April 14, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 887: Bonfire of the monocytes
TWiV explains why this season’s influenza vaccine is not protecting against mild to moderate disease caused by H3N2 virus, and that antibody-dependent entry of SARS-CoV-2 into monocytes is a major contributor to severe COVID-19. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Seasonal influenza vaccine effectiveness (MMWR) Properties of a dominant H3N2 variant (bioRxiv) Scott Henley on influenza vaccine growth in eggs (TWiV 480) Fc receptor dependent entry of SARS-CoV-2 into ...
Source: This Week in Virology - MP3 Edition - April 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 886: COVID-19 clinical update #109 with Dr. Daniel Griffin
In COVID-19 clinical update #109, Daniel Griffin discusses cardiac complications after infection or vaccination, long COVID in children, fourth vaccine dose in Israel, no need for fourth vaccine does in EU, dexamethasone dosing, immunomodulation therapy, MIS outcomes in children, US long COVID effort launched, and herd immunity. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Cardiac complications after infection or vaccination (MMWR) Long COVID in children (Future Med) Fourth vaccine dose in Israel (NEJM) No need for fourth vaccine dose (Eur Med Agency)...
Source: This Week in Virology - MP3 Edition - April 9, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 885: Russian bats and Ankara vectors
TWiV reveals an ACE2-dependent sarbecovirus from Russian bats that is not inhibited by anti-SARS-CoV-2 antibodies, and a modified vaccinia virus Ankara vectored vaccine that protects nonhuman primates from Delta infection. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Sarbecovirus from Russian bat (bioRxiv) MVA vectored COVID vaccine (Sci Immunol) Letters read on TWiV 885 Timestamps by Jolene. Thanks! Weekly Picks Brianne – The Search for a Model Octopus That Won’t Die After Laying Its Eggs...
Source: This Week in Virology - MP3 Edition - April 7, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Sotrovimab for Mild to Moderate COVID-19, Myocardial Infarction After Hepatitis B Vaccine, Review of Antiseizure Medications for Epilepsy, and more
Editor’s Summary by Christopher Muth, MD, Senior Editor of JAMA, the Journal of the American Medical Association, for the April 5, 2022 issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - April 5, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 883: COVID-19 clinical update #108 with Dr. Daniel Griffin
In COVID-19 clinical update #107, Daniel Griffin reviews vaccine booster doses, at-home testing, transmission in ferrets, improving indoor air quality, trials of BCG, ivermectin, and fluvoxamine, vaccination during pregnancy, mRNA vaccines and Fc functions, anti-platelet and aspirin therapy and a trial of prone positioning. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode FDA authorizes second booster (FDA) Second booster and mortality (Res Square) Booster effectiveness vs hospitalization (MMWR) SARS-CoV-2 confections (Lancet) At-home testing (MMWR) Transm...
Source: This Week in Virology - MP3 Edition - April 2, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 882: Elispot on about T cells and lipids
Vincent and Brianne review the need to better understand T cell responses to SARS-CoV-2 infection to better inform public health decisions, and how IL-1 and IL-1ra are important regulators of the inflammatory response to RNA vaccines. Hosts: Vincent Racaniello and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Understanding T cell responses during COVID-19 (Science Immunol) IL-1 and IL-1ra are keys to inflammation after RNA vaccination (Nature Immunol) Letters read on TWiV 882 Timestamps by Jolene. Thanks! Weekly Picks Brianne – Covid r...
Source: This Week in Virology - MP3 Edition - March 31, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Covid vaccine safety, Methenamine hippurate, and intersectionality
In this episode of Talk Evidence, Helen Macdonald, the BMJ ’s research integrity editor is joined by Joe Ross, US research editor, and Juan Franco, editor in chief of BMJEBM, to talk about all things evidence. Joe gives us an update about covid, including new research on safety of the vaccine Association between covid-19 vaccination, SARS-CoV-2 infectio n, and risk of immune mediated neurological events https://www.bmj.com/content/376/bmj-2021-068373 Juan updates us on a potential new prophylactic for recurrent UTIs, Methenamine hippurate, which could be an alternative to antibiotics. Alternative to prophylactic antibi...
Source: The BMJ Podcast - March 30, 2022 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Covid vaccine safety, Methenamine hippurate, and intersectionality
In this episode of Talk Evidence, Helen Macdonald, the BMJ’s research integrity editor is joined by Joe Ross, US research editor, and Juan Franco, editor in chief of BMJEBM, to talk about all things evidence. Joe gives us an update about covid, including new research on safety of the vaccine Association between covid-19 vaccination, SARS-CoV-2 infection, and risk of immune mediated neurological events https://www.bmj.com/content/376/bmj-2021-068373 Juan updates us on a potential new prophylactic for recurrent UTIs, Methenamine hippurate, which could be an alternative to antibiotics. Alternative to prophylactic antibiot...
Source: The BMJ Podcast - March 30, 2022 Category: General Medicine Authors: BMJ Group Source Type: podcasts

TWiV 880: COVID-19 clinical update #107 with Dr. Daniel Griffin
In COVID-19 clinical update #107, Daniel Griffin discusses Moderna vaccine results in children, hospitalization by ethnicity, BA.2 severity in children, placentitis and thrombohematoma during pregnancy, predictive value of symptoms for diagnosis, Evusheld activity against BA.1 and BA.2, Remdesivir resistance, Ivermectin with and without strongyloidiasis, inhaled ciclesonide, home telemonitoring, pulse oximetry for remote monitoring, effectiveness of anti-platelet therapy, and deaths in Zambia. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Moderna vaccin...
Source: This Week in Virology - MP3 Edition - March 26, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 877: COVID-19 clinical update #106 with Dr. Daniel Griffin
In COVID-19 clinical update #106, Daniel Griffin covers failure of ivermectin to improve hospitalization, increased hospitalization of children with Omicron, seroconversion of children versus adults, effectiveness of Pfizer mRNA vaccine in children, high vaccine effectiveness in Finland against Omicron, distinct long COVID clinical phenotypes, and estimating worldwide excess mortality. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Ivermectin did not reduce hospitalizations (Wall St J) Increased hospitalization of children with Omicron (MMWR) Seroconver...
Source: This Week in Virology - MP3 Edition - March 19, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: How vaccine complacency is plaguing 'COVID zero' strategies
A handful of states around the world have pursued 'COVID zero' strategies. Through a combination of intensive lockdowns, travel restrictions and comprehensive test and trace systems, regions like Tonga, New Zealand, Taiwan, mainland China and Western Australia managed to keep the virus at bay. But now many of these countries are facing new outbreaks on a scale they have not yet seen, and it is being driven in part by vaccine hesitancy. In this episode of Coronapod we discuss how a successful public health campaign can breed new problems when it comes to public perception of risk, and ask how vaccine complacency m...
Source: Nature Podcast - March 18, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts