Evaluating the Effectiveness of Bivalent COVID-19 Vaccines in Children and Adolescents
Bivalent mRNA COVID-19 vaccines were recommended for children and adolescents aged 5 to 17 years in the US, but were they effective? JAMA Associate Editor Tracy A. Lieu, MD, MPH, spoke with author Leora R. Feldstein, PhD, US Centers for Disease Control and Prevention, about the effectiveness of bivalent COVID-19 vaccines in children and adolescents. Related Content: Effectiveness of Bivalent mRNA COVID-19 Vaccines in Preventing SARS-CoV-2 Infection in Children and Adolescents Aged 5 to 17 Years (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - February 6, 2024 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Cervical cancer could be eliminated: here's how
Cervical cancer is both treatable and preventable, and the WHO has called for countries to come together to to eliminate the disease in the next century.However the disease still kills over 300,000 people each year, and levels of screening, treatment and vaccination need to be stepped up in order to achieve this goal.These challenges are particularly stark in low- and middle-income countries, where a lack of funding, staffing and infrastructure are obstacles. Vaccine hesitancy, especially in light of the COVID-19 pandemic, is also a key problem.In this Podcast Extra, two experts share their thoughts on how best to overcome...
Source: Nature Podcast - February 4, 2024 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 1084: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the how the pandemic influenced the healthcare job market before he reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, discusses the safety of the prefusion RSV vaccine, if high or moderate dose of the quadrivalent influenza vaccine is better for protection against hospitalization, summarizes the new WHO COVID guidelines, revisits how to prevent pathogen transmission in healthcare setting, the under use of COVID oral antiviral and what occurs in persistently...
Source: This Week in Virology - MP3 Edition - February 3, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1082: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, before discussing viral transmission to adults in healthcare setting, the recently EUA approved protein based COBREVAX vaccine, reviews quarantine guidelines, the use of simnotrelivr for mild to moderate COVID-19, how viral RNA may persist in your cell culture dish following antiviral therapy, continues to dispel the myth of viral rebound, how to pay for Paxlovid, , when to use steroids and the benefits of convalescen...
Source: This Week in Virology - MP3 Edition - January 27, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1080: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US before discussing vaccine effectiveness in children and adolescents, how the pandemic impacted the socioemotional development of infants and toddlers, continues to dispel the myth of viral rebound, how to pay for Paxlovid, reviews quarantine guidelines, when to use steroids and the benefits of convalescent plasma, examines the role of immune aberrations in long COVID and how vaccination may protect against developing long COVID. Subscribe (free): Apple ...
Source: This Week in Virology - MP3 Edition - January 20, 2024 Category: Virology Authors: VIncent Racaniello Source Type: podcasts

TWiV 1078: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin reviews recent measles outbreaks, prequalification of nOPV2 by the WHO and most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US before discussing COVID-19 deaths linked to SNPs in C-reactive protein, spread of recent viral variants, how early vaccination reduced hospitalization of those infected with XBB.1.5, reviewed quarantine guidelines, how oral antivirals reduce hospitalizations, dissociation of antiviral treatment from infection rebound, and long COVID, deaths due to administration of hydroxychloroquine, mus...
Source: This Week in Virology - MP3 Edition - January 13, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1079: Rock of phages
TWiV reveals how viruses participate in the organomineralization of travertines, and how neutralizing antibodies evolve to exploit vulnerable sites in the hepatitis C virus envelope glycoprotein E2 and mediate clearance of infection. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dick...
Source: This Week in Virology - MP3 Edition - January 13, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1076: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin highlights global circulation of Mpox virus, reviews the most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US, and discusses the clinical outcome of hospitalized children under 5 years infected with SARS-CoV-2, the perinatal and neonatal outcomes including adverse effects of SARS-CoV-2 infection and virus transmission in Italy between early 2020 and 2022, the guidelines to improve home ventilation, the safety and efficacy of the oral anti-viral molnupiravir and the use of convalescent plasma as a long term treatme...
Source: This Week in Virology - MP3 Edition - January 6, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1074: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the outcomes of SARS-CoV-2, influenza and respiratory syncytial virus infection in pediatric communities under the age of 18 years, the treatment of infants with the human monoclonal anti-respiratory syncytial virus antibody to prevent hospitalizations, most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US, how the SARS-CoV-2/COVID-19 pandemic affected school attendance and child healthcare, how exposure length influenced transmission of SARS-CoV-2, how the durability of the anti-SARS-CoV-2 antibody respo...
Source: This Week in Virology - MP3 Edition - December 30, 2023 Category: Virology Authors: VIncent Racaniello Source Type: podcasts

TWiV 1072: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the annual economic burden of respiratory syncytial virus in adults in the US, recombinant or standard-dose influenza vaccine in adults under 65 years of age, maternal vaccine effectiveness against influenza-associated hospitalizations and emergency department visits in iInfants, influenza positive tests reported to CDC by US clinical laboratories, update on COVID-19, risk of severe maternal morbidity associated with SARS-CoV-2 infection during pregnancy, COVID-19 rapid antigen tests with self-collected vs health care worker–collected nasal and throat swab specimens, op...
Source: This Week in Virology - MP3 Edition - December 23, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1070: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses monkeypox and chickenpox co-infection in southern Nigeria, vaccine effectiveness against influenza A, SARS-CoV-2 neutralizing antibody titers in maternal blood, umbilical cord blood, and breast milk, COVID-19 rapid antigen tests with self-collected vs health care worker–collected nasal and throat swab specimens, four methods for monitoring SARS-CoV-2 and Influenza A virus activity in schools, efficacy and safety of Baricitinib for the treatment of hospitalized adults with COVID-19, a synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong, consisten...
Source: This Week in Virology - MP3 Edition - December 16, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Inhaled vaccine prevents COVID in monkeys
Current COVID-19 vaccines offer great protection from serious illness, but they don't prevent people from becoming infected in the first place. Because of this, researchers have been searching for ways to boost mucosal immunity — the immune response on mucosal surfaces — as this is where the virus is first encountered by the body. Now a team have shown that mucosal immunity can be improved enough to block infection in rhesus macaques by administering booster vaccines directly into their lungs, through inhalation. They hope this could offer a way to stop humans getting COVID-19 in the ...
Source: Nature Podcast - December 14, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 1066: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses a microbiologist who was harassed during COVID pandemic sues university, use of inactivated poliovirus vaccine for poliovirus outbreak response, safety and immunogenicity of bivalent rsvpref vaccine coadministered with seasonal inactivated influenza vaccine in older adults, coffee as a dietary strategy to prevent SARS-CoV-2 infection, enrollment of pediatric patients in COVID-19 interventional trials, vaccination, immunity, and the changing impact of COVID-19 on infant health, COVID-19 vaccine effectiveness against post- COVID -19 condition among 589722 individuals in Sw...
Source: This Week in Virology - MP3 Edition - December 2, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

The future of the winter ’flu season
We were accepting of an increase in deaths every winter 'flu season, but Ashish Jha thinks that is not longer a tenable position. Lessons he learned during his time as the White House Covid-19 coordinator have convinced him we should be taking a different approach to the winter season. In this interview with Mun-Keat Looi, The BMJ's international features editor, we hear about living with COVID, the future of antivirals, vaccines, and surveillance. They talk about long COVID, the investment required to fight future outbreaks effectively, and the role of the US in the global health response.     (Source: The BMJ Podcast)
Source: The BMJ Podcast - December 1, 2023 Category: General Medicine Authors: BMJ Group Source Type: podcasts

TWiV 1065: Cat coronavirus gains function in Cyprus
TWiV reviews ban on gain-of-function research by the House, chronic wasting disease in Tennessee deer, nOPV2 causing paralysis in children, and an outbreak of feline infectious peritonitis in Cyprus caused by a new recombinant coronavirus. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Di...
Source: This Week in Virology - MP3 Edition - November 26, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts