TWiV 874: COVID-19 clinical update #105 with Dr. Daniel Griffin
In COVID-19 clinical update #105, Daniel Griffin discusses changes in brain structure after infection, dementia in patients with pneumonia, Paxlovid in children, mask effectiveness in schools, host factors and severe disease, post-acute symptoms, and the mission of CEPI. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Infection and changes in brain structure (Nature) Dementia among pneumonia survivors (Open Forum Inf Dis) Narrative dynamics around COVID-19 vaccines (FSI) Children and COVID (AAP) Paxlovid in pediatric patients (Pfizer) Mask effectiveness i...
Source: This Week in Virology - MP3 Edition - March 12, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Rural healthcare in a pandemic
In this episode of the podcast we ’re going to be talking about rural healthcare - and specifically the difficulties that distance, demographics, and funding have introduced into the world’s covid-19 response. Rural regions made vulnerable by limited healthcare infrastructure, lower rates of vaccination, and opposition to gover nment policies are the new frontlines in the pandemic, but support systems have not adjusted to the growing rural needs for health education, testing, vaccination, and treatment.Michael Forster Rothbart, Kata Kar áth, and Lungelo Ndhlovu report from the US, Ecuador, and Zimbabwe (Source: The BMJ Podcast)
Source: The BMJ Podcast - March 7, 2022 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Rural healthcare in a pandemic
In this episode of the podcast we’re going to be talking about rural healthcare - and specifically the difficulties that distance, demographics, and funding have introduced into the world’s covid-19 response. Rural regions made vulnerable by limited healthcare infrastructure, lower rates of vaccination, and opposition to government policies are the new frontlines in the pandemic, but support systems have not adjusted to the growing rural needs for health education, testing, vaccination, and treatment. Michael Forster Rothbart, Kata Karáth, and Lungelo Ndhlovu report from the US, Ecuador, and Zimbabwe (Source: The BMJ Podcast)
Source: The BMJ Podcast - March 7, 2022 Category: General Medicine Authors: BMJ Group Source Type: podcasts

TWiV 872: COVID-19 clinical update #104 with Dr. Daniel Griffin
In COVID-19 clinical update #104, Daniel Griffin reviews effectiveness of mRNA vaccines among children, number of children affected by disease, accuracy of rapid antigen tests, CDC guidance for prevention strategies, monoclonal antibody effectiveness, predicting progression to severe respiratory failure from pneumonia, risk of long COVID after two vaccine doses, and peripheral neuropathy in long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Vaccine effectiveness 5-11 year olds (medRxiv) Vaccine effectiveness vs ED and UCE 5-12 year olds (medRxiv)...
Source: This Week in Virology - MP3 Edition - March 5, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 870: COVID-19 clinical update #103 with Dr. Daniel Griffin
In COVID-19 clinical update #102, Daniel Griffin covers immunocompromised people, hospitalization of children, vaccine usage update, Omicron and cross-reactive neutralizing antibodies, reinfection prevents disease in hamsters, repeated infections with endemic coronaviruses, global burden of antimicrobial resistance, ivermectin not protective in hamsters, and Omicron evades therapeutic monoclonals. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode What does society owe immunocompromised people (Atlantic) Prevalence of immunosuppression in US (JAME) Hospitali...
Source: This Week in Virology - MP3 Edition - February 26, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

JAMA Otolaryngology –Head & Neck Surgery : Association Between COVID-19 Vaccine and Sudden Sensorineural Hearing Loss
Interview with Ilana Doweck, MD, author of Association Between the BNT162b2 Messenger RNA COVID-19 Vaccine and the Risk of Sudden Sensorineural Hearing Loss, and Eric J. Formeister, MD, MS, author of Assessment of Sudden Sensorineural Hearing Loss After COVID-19 Vaccination Hosted by Joseph P. Bradley, MD. (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - February 24, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

TWiV 868: COVID-19 clinical update #102 with Dr. Daniel Griffin
In COVID-19 clinical update #102, Daniel Griffin reviews children and COVID, effectiveness of maternal vaccination, vaccines for immunocompromised, primary care physicians and vaccination rates, booster safety among adults, placentitis, azithromycin, oral Nirmatrelvir, Omicron antibody evasion, EUA for bebtelovimab, IL-1 blocking agents, thromboprophylaxis, effectiveness of vaccines against long COVID, and risks of mental health outcomes. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Children and COVID state data (AAP) Effectiveness of maternal vaccina...
Source: This Week in Virology - MP3 Edition - February 19, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Prevention of Self-harm in Adults With Suicidal Ideation, Symptomatic Omicron and Delta SARS-CoV-2 Infection Following Vaccination, Outcomes of Lung Transplant for COVID-19 ARDS, and more
Editor's Summary by Preeti Malani, MD, Associate Editor of JAMA, the Journal of the American Medical Association, for the February 15, 2022, issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - February 15, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 866: EV antibodies rEVolutionize our thinking
Amy returns to TWiV to discuss her work on the identification of cross-reactive antibody responses among diverse enteroviruses, and the implications for our understanding of viral pathogenesis and seroprevalence studies. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit Brianne Barker, and Amy Rosenfeld Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ABRCMS ePoster Spring Symposium for Emerging Scientists Cross-reactive enterovirus antibodies (mBio) Poliovirus receptor transgenic mice (virology blog) Timestamps by Jolene. Thanks! Weekly Picks Di...
Source: This Week in Virology - MP3 Edition - February 13, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 865: COVID-19 clinical update #101 with Dr. Daniel Griffin
In COVID-19 clinical update #101, Daniel Griffin discusses children and COVID, human challenge study results, effectiveness of mask use, Omicron boost in macaques, mucosal vaccine candidate, long-term cardiovascular outcomes, and global vaccine perceptions. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Children and COVID state data (AAP) Human challenge study (Res Sq) Effectiveness of mask use (MMWR) Omicron boost in macaques (bioRxiv) Mucosal vaccine candidate (Cell) Long-term cardiovascular outcomes (Nat Med) Global vaccine perceptions (PLoSNTD) Lette...
Source: This Week in Virology - MP3 Edition - February 12, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: How African scientists are copying Moderna's COVID vaccine
Vaccine inequity continues to be one of the greatest challenges in the pandemic - with only 10% of those in low- and middle-income countries fully vaccinated. One of the biggest hold-ups is a lack of vaccine manufacturing capacity in poorer nations. But now, researchers at the WHO technology-transfer hub have completed the first step in a project aimed at building vaccine manufacturing capacity in the Global South, by successfully replicating Moderna's COVID vaccine without assistance from the US-based biotech company. In this episode of Coronapod, we ask how they did it? What happens next? What the legal ramification...
Source: Nature Podcast - February 11, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: How African scientists are copying Moderna's COVID vaccine
Vaccine inequity continues to be one of the greatest challenges in the pandemic - with only 10% of those in low- and middle-income countries fully vaccinated. One of the biggest hold-ups is a lack of vaccine manufacturing capacity in poorer nations. But now, researchers at the WHO technology-transfer hub have completed the first step in a project aimed at building vaccine manufacturing capacity in the Global South, by successfully replicating Moderna's COVID vaccine without assistance from the US-based biotech company. In this episode of Coronapod, we ask how they did it? What happens next? What the legal ramification...
Source: Nature Podcast - February 11, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 862: COVID-19 clinical update #100 with Dr. Daniel Griffin
In COVID-19 clinical update #100, Daniel Griffin, from Accra, Ghana, reviews the challenges in evaluating Omicron severity, over 800 deaths in children, Pfizer vaccine EUA application for under 5 year olds, false positives from soft drinks, Novavax vaccine EUA application, childhood experiences and vaccine hesitancy, fourth vaccine dose in Israel, effects of antivirals and monoclonals against Omicron, and multiple factors associated with PASC. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Omicron severity challenges (NEJM) Children and COVID data (AAP) ...
Source: This Week in Virology - MP3 Edition - February 5, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 860: Evading a Toll on the road to RNA vaccines
TWiV reviews a seminal paper showing that chemically modified bases in RNAs suppress recognition by Toll-like receptors, a finding that that was essential for the development of COVID-19 mRNA vaccines. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Vaccine Town Hall (ASV) Columbia University BSL-3 Manager position RNA modifications suppress innate recognition (Immunity) Critical contribution of pseudouridine (Front Cell Dev Biol) Rich Condit reminisces (YouTube) Letters read ...
Source: This Week in Virology - MP3 Edition - January 30, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 859: COVID-19 clinical update #99 with Dr. Daniel Griffin
In COVID-19 clinical update #99, Daniel Griffin discusses Omicron disease severity, neurologic manifestations in children, testing outcomes during multiple infections, boosters improve VE and VD, booster efficacy for ED and UC encounters, vaccines induce cross-protective T cell memory, and indications for monoclonal antibody therapy.C Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Omicron disease severity (MMWR) Neurologic manifestations in children (Pediatric Neurol) Respiratory virus interference (Emerg Inf Dis) Hospitalization by vaccination status (C...
Source: This Week in Virology - MP3 Edition - January 29, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts