Fight Aging! Newsletter, May 22nd 2017
In this study, researchers analysed data of millions of British patients between 1995 and 2015 to see if this claim held true. They tracked people who were obese at the start of the study, defined as people with a body mass index (BMI) of 30 or more, who had no evidence of heart disease, high blood pressure, high cholesterol or diabetes at this point. They found these people who were obese but "metabolically healthy" were at higher risk of developing heart disease, strokes and heart failure than people of normal weight. No such thing as 'fat but fit', major study finds Several studies in the past have sug...
Source: Fight Aging! - May 21, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Excess Weight Increases Disease Risk and Shortens Life
In this study, researchers analysed data of millions of British patients between 1995 and 2015 to see if this claim held true. They tracked people who were obese at the start of the study, defined as people with a body mass index (BMI) of 30 or more, who had no evidence of heart disease, high blood pressure, high cholesterol or diabetes at this point. They found these people who were obese but "metabolically healthy" were at higher risk of developing heart disease, strokes and heart failure than people of normal weight. No such thing as 'fat but fit', major study finds Several studies in the past have sug...
Source: Fight Aging! - May 17, 2017 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, April 10th 2017
This study shows that lifespan-extending conditions can slow molecular changes associated with an epigenetic clock in mice livers. Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions Age-associated epigenetic changes are implicated in aging. Notably, age-associated DNA methylation changes comprise a so-called aging "clock", a robust biomarker of aging. However, while genetic, dietary and drug interventions can extend lifespan, their impact on the epigenome is uncharacterised. To fill this knowledge gap, we defined age-assoc...
Source: Fight Aging! - April 9, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Astaxanthin Increases FOXO3 Levels, Outcomes on Health Yet to be Determined
As the publicity materials here note, at least one research group is working on ways to enhance the gene expression of FOXO3, seeing this as a way to favorably adjust the operation of metabolism so as to modestly slow the effects of aging. The researchers have demonstrated enhanced gene expression in mice, but have yet to follow up to show that improved health and longevity result from the application of this method. That might be reasonably expected to occur to some degree, based on other investigations of this gene, and of the particular approach used here. Researchers have announced the results of an animal stu...
Source: Fight Aging! - April 5, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Eating better: 3 keys to healthy grocery shopping
With the New Year a few months behind us now, hectic schedules and daily distractions have gotten in the way of our most well intended resolutions. If you are still looking to work on being healthier this year, eating healthier is a good option that may be easier than it seems. As Hippocrates (the “father” of modern medicine) once said, “Let food be thy medicine, and thy medicine thy food.” We are realizing more and more how much our daily behaviors and our food choices impact our health and well-being. There are many factors that can get in the way of our efforts to lead a healthy lifestyle including busy schedule...
Source: Harvard Health Blog - March 24, 2017 Category: Consumer Health News Authors: Dominic Wu, MD Tags: Health Healthy Eating Source Type: blogs

Hypotension Evidence Supports Views of Blood Supply as Important in Dementia
The evidence presented here is supportive of views on neurodegeneration that place an emphasis on blood supply to the brain. Certainly, the aging of the cardiovascular system is strongly implicated in some forms of dementia, but not always necessarily because of a lessening supply of oxygen and nutrients. The more common picture is of small amounts of damage caused by tiny blood vessel ruptures that add up over time, but the brain is an energetic organ; it is very possible that declining supply from the circulatory system is a contributing factor. Middle-aged people who experience temporary blood pressure drops th...
Source: Fight Aging! - March 13, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Early Coronary Artery Calcification Predicts Later Risk of Heart Disease
Researchers here find that even quite low levels of calcification of arteries at younger ages associates with a raised risk of heart disease going forward. Calcification is a process that has is yet to be firmly placed in the chain of cause and consequence for age-related damage in blood vessel tissues. The evidence leans towards it being a consequence of primary damage such as waste accumulating in cell lysosomes, forms of persistent cross-linking that stiffen blood vessels and senescent cell accumulation that produces inflammation, insofar as growing calcification appears to be a cellular process, the result of changed a...
Source: Fight Aging! - February 9, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Can These Healthy Lifestyle Changes Prevent Stroke?
This study also assessed how risk factors vary between stroke subtype, throughout the world, and according to age or sex. Overall, it was established that over 90% of the worldwide risk of stroke can be attributed to only ten risk factors: hypertension, low physical activity, high apolipoprotein (Apo)B/ApoA1 ratio (predictor of coronary heart disease risk), diet, abdominal obesity, psychosocial factors, current smoking, cardiac causes, alcohol consumption, and diabetes. Of these, hypertension was identified as the most important risk factor for stroke. Some risk factors were shown to be predominantly associated with a subt...
Source: World of Psychology - January 24, 2017 Category: Psychiatry & Psychology Authors: Psych Central Staff Tags: Brain and Behavior Brain Blogger Exercise & Fitness Health-related Publishers Research Self-Help Healthy Lifestyle Changes risk factors for stroke Sara Adaes PhD stroke prevention Source Type: blogs

Top 10 Healthy Foods That Fight Stress
You're reading Top 10 Healthy Foods That Fight Stress, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. Nowadays, many people suffer from stress due to busy lifestyles. In fact, too much stress may cause a lot of side effects on the mood, behavior, and body. It may even result in short-term and long-term physical issues such as impaired learning ability, impaired memory, high blood pressure, osteoporosis, a weak immune system, and coronary heart disease. Keeping a healthy lifestyle and having a proper diet will help to c...
Source: PickTheBrain | Motivation and Self Improvement - January 16, 2017 Category: Consumer Health News Authors: Ann Nguyen Tags: depression diet featured health and fitness self improvement antioxidants best self-improvement blogs diet and stress foods to beat stress home remedies pickthebrain trending diets Source Type: blogs

Saturated Fats Linked To Heart Disease Once Again
–But critics say that observational studies can’t establish causal relationship. A prominent group of nutrition researchers have once again linked saturated fats to increased coronary heart disease. The new paper, published in BMJ, is the third paper in the past year to decry saturated fats. Along with the previous two papers, published in JACC and JAMA Internal...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - November 27, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Prevention, Epidemiology & Outcomes cholesterol diet dietary guidelines nutrition saturated fats Source Type: blogs

Measuring the Effects of Prevention on Heart Disease
Despite the rising proportion of the older population who choose to be overweight or obese, risk of heart disease has declined somewhat in past few decades. This outcome can be attributed to prevention in the sense of at least some people taking better care of their health by specifically targeting measures such as blood pressure and blood lipid levels, coupled with prevention in the sense of treatments such as statins that also reliably influence these measures. Increased blood pressure with age, or hypertension, directly impacts risk of cardiovascular disease and other conditions by putting additional stress on tissue st...
Source: Fight Aging! - November 14, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

What is " Truthful and Non-misleading? " That is the Question FDA Must Answer to Allow Off-Label Communications by Pharma
Yesterday, I attended and presented atFDA ' s Public Hearing on drug company communications regarding unapproved uses of drugs. My presentation had to do with off-label promotion directed at consumers and patients (find ithere on Slideshare).Just a few takeaways.The phrase " truthful and non-misleading " was mentioned several times during the meeting, including by PhRMA (read "BIO #Pharma Industry Offers Its Own Set of Off-Label Communications Principles" ). But defining what is true and non-misleading is difficult as many presenters noted. Something can be truthful but also misleading as pointed out by Dr. Aaron Kesselhei...
Source: Pharma Marketing Blog - November 10, 2016 Category: Pharmaceuticals Tags: FDA off-label promotion Source Type: blogs

There ’s no sugar-coating it: All calories are not created equal
Counting calories doesn’t work. Burning more calories each day than you consume may have been the diet advice from the past, but that has since been debunked. So you no longer have to work out until you’ve “burned off” that apple cider donut you had with lunch. You just have to make sure you’re eating whole foods and avoiding processed carbohydrates — like crackers, cookies, or white bread. A recent review in JAMA Internal Medicine further casts a light on the shaky history of nutritional science. Before the 1980s, regulations did not require researchers and physicians to declare conflicts of interest before pu...
Source: Harvard Health Blog - November 4, 2016 Category: Consumer Health News Authors: Celia Smoak Spell Tags: Diabetes Diet and Weight Loss Health Healthy Eating Source Type: blogs

Does The Hospital Compare 5-Star Rating Promote Public Health?
The Centers for Medicare and Medicaid Services (CMS) recently released summary “5-star” scores for hospitals on its Hospital Compare website. In advance of the release and since, hospitals have criticized these scores as inaccurate and unfair. In defense of the scores, CMS and various other stakeholders have cited the need for quality transparency that consumers can use to help guide choice of health care providers. Both are right. The reason we measure and publicly report quality is to facilitate improvements in the health of the population by a) informing consumers about high- or low-quality providers that th...
Source: Health Affairs Blog - September 8, 2016 Category: Health Management Authors: Catherine MacLean and Louis Shapiro Tags: Featured Hospitals Public Health Quality Hospital Compare 5-star summary quality measures quality rating system Source Type: blogs

Fight Aging! Newsletter, September 5th 2016
This study is a good example of the degree to which the choice to remain active in later life makes a difference. That implies a range of other choices over the decades in order to raise the odds that you can in fact choose to remain active when older, such as avoiding weight gain. Moderate physical activity is associated with a greater than 50% reduction in cardiovascular death in over-65s. The 12 year study in nearly 2500 adults aged 65 to 74 years found that moderate physical activity reduced the risk of an acute cardiovascular event by more than 30%. High levels of physical activity led to greater risk reducti...
Source: Fight Aging! - September 4, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs