Health Tip: Coping With Cold Sores
-- Cold sores are small blisters, triggered a herpes virus, that mostly form on the mouth.
The American Academy of Dermatology suggests how to cope with them:
Apply an over-the-counter antiviral cold-sore medication that contains docosanol or... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 12, 2017 Category: General Medicine Source Type: news
Health Tip: Coping With Cold Sores
Title: Health Tip: Coping With Cold SoresCategory: Health NewsCreated: 5/12/2017 12:00:00 AMLast Editorial Review: 5/12/2017 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - May 12, 2017 Category: Dermatology Source Type: news
First study of Oncolytic HSV-1 in children & young adults with cancer indicates safety, tolerability
(Nationwide Children's Hospital) HSV1716 -- an oncolytic herpes simplex virus-1 -- has been studied in adults via injection into the brain and superficial tumors. Now, a team of researchers at Nationwide Children's Hospital and Cincinnati Children's Hospital Medical Center have completed the first phase 1 trial of the virus in the pediatric population, published online in Clinical Cancer Research. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 11, 2017 Category: Cancer & Oncology Source Type: news
Case 2: Herpes Simplex Virus Infection in a Preterm Infant and Complications
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Kojima, K., Schein, R., Karna, P. Tags: Pediatric Drug Labeling Update Index of Suspicion in the Nursery Source Type: news
Why is herpes simplex virus disease risk so much greater for newborns?
(Mary Ann Liebert, Inc./Genetic Engineering News) Interferon is a crucial component of the human immune system's response to infection by herpes simplex virus type 1 (HSV-1), but how important a role it plays in determining the severity of disease and explaining why newborns are so much more susceptible to HSV-1 infection than adults remains unclear. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 28, 2017 Category: Global & Universal Source Type: news
Understanding of herpesvirus infection advanced by new research
Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle has frustrated scientists for years. Now, scientists have identified a set of protein complexes that are recruited to viral genes and stimulate both initial infection and reactivation from latency. Environmental stresses known to regulate these proteins also induce reactivation. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 12, 2017 Category: Science Source Type: news
NIH scientists advance understanding of herpesvirus infection
(NIH/National Institute of Allergy and Infectious Diseases) Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle has frustrated scientists for years. Now, National Institutes of Health (NIH) scientists have identified a set of protein complexes that are recruited to viral genes and stimulate both initial infection and reactivation from latency. Environmental stresses known to regulate these proteins also induce reactivation. (Source: EurekAlert! - Infec...
Source: EurekAlert! - Infectious and Emerging Diseases - April 12, 2017 Category: Infectious Diseases Source Type: news
What Causes Uveitis?
Discussion
Inflammation of the middle layer of the eye, or uvea, is termed uveitis. Uveitis can be divided into anterior, intermediate or posterior uveitis by involving the anterior (iris and ciliary body), intermediate (vitreous) or posterior (choroid and usually retina) compartments. Panuveitis involves all 3 compartments. Duration can also be used to classify uveitis. Acute is 6 weeks and > 3 months is chronic persistent uveitis. Episodic periods of inactivity and reactivity that last more than 3 months are called recurrent uveitis. A third way to characterize uveitis is if it is granulomatous or not. Uveitis increas...
Source: PediatricEducation.org - April 3, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Herpes STDs: From chimps to humans to cold sore cousin mixing before worldwide spread
(Molecular Biology and Evolution (Oxford University Press)) Evolutionarily, Herpes simplex virus 1 and 2 are considered cousins, and are thought to have evolved independently, Now, an entirely new picture is emerging. While scientists did not find evidence of chimpanzee herpes virus fragments in HSV-2 genomes, they show the history of HSV-2 was marked by recombination with HSV-1. In addition, they determined two main lineages of HSV-2, one globally distributed and another restricted to sub-Saharan Africa, which both started diversifying about 30,000 years ago. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 28, 2017 Category: Infectious Diseases Source Type: news
Autism Linked to Herpes Infection in Pregnancy Autism Linked to Herpes Infection in Pregnancy
High levels of maternal antibodies against herpes simplex virus 2 in mid-pregnancy may increase the risk for autism spectrum disorder.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - March 1, 2017 Category: Psychiatry Tags: Psychiatry News Source Type: news
Link between herpes in pregnancy and autism is unconfirmed
Conclusion
This was a Norwegian case-control study that looked at whether maternal infections during pregnancy are associated with the risk of neurological developmental disorders such as autism spectrum disorders (ASDs) in their children.
The study initially found no association between any of the pathogens during pregnancy or after delivery, and the development of ASD in boys or girls.
Further investigations suggested that high levels of HSV-2 virus antibodies during mid-pregnancy were associated with increased risk of the development of ASD in boys.
The researchers suggest that the suspected risk of ASD associated wit...
Source: NHS News Feed - February 24, 2017 Category: Consumer Health News Tags: Pregnancy/child Neurology Mental health Source Type: news
Medical News Today: Genital herpes in pregnancy may raise autism risk for offspring
Researchers suggest that mothers with a greater immune response to herpes simplex virus 2 in pregnancy may be more likely to have children with autism. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 22, 2017 Category: Consumer Health News Tags: Autism Source Type: news
What Causes Hyperammonemia?
Discussion
Reye’s syndrome (RS)is named for Dr. Douglas Reye who along with Drs. G. Morgan and J. Baral described encephalopathy and fatty accumulation and degeneration in children in a 1963 Lancet article. RS usually affects children but can occur at all ages. All organs can be affected but the liver and brain are primarily affected causing liver failure and encephalopathy as toxic metabolites (especially ammonia) accumulate, and intracranial hypertension and cerebral edema occurs. As the ammonia levels begin to rise (> 100 mg/dL) patients lose their appetite, have nausea and emesis and mental status changes whic...
Source: PediatricEducation.org - February 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Ocular Complications of Congenital Infections
This article summarizes the ocular complications of the 5 infections typically represented by the acronym TORCHES (toxoplasmosis, rubella, cytomegalovirus, herpes simplex, and syphilis), as well as others, including newer pathogens such as the human immunodeficiency, West Nile, and Zika viruses. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - January 31, 2017 Category: Pediatrics Authors: Khazaeni, L. M. Tags: Pediatric Drug Labeling Update Articles Source Type: news
New genital herpes vaccine candidate provides powerful protection in preclinical tests
Approximately 500 million people around the world are infected with the genital herpes virus known as herpes simplex virus 2 (HSV2). A vaccine that could bring an end to this global pandemic is needed desperately, yet no candidate vaccine has ever performed well in clinical trials. Now scientists in the Perelman School of Medicine at the University of Pennsylvania have shown that a new type of vaccine provides powerful protection in standard guinea pig and monkey models of HSV2 infection. (Source: World Pharma News)
Source: World Pharma News - January 24, 2017 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
