HSV Vaccine Linked to Lower Viral Shedding (CME/CE)
DENVER (MedPage Today) -- A therapeutic vaccine for herpes simplex type 2 (HSV-2) virus reduced viral shedding and had an acceptable safety profile, researchers reported here. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - September 14, 2013 Category: Infectious Diseases Source Type: news

Programmed cell death activates latent herpesviruses
Researchers have found that apoptosis, a natural process of programmed cell death, can reactivate latent herpesviruses in the dying cell. The results of their research, which could have broad clinical significance since many cancer chemotherapies cause apoptosis, was published ahead of print in the Journal of Virology. Human herpesviruses (HHV) are linked to a range of childhood and adult diseases, including chickenpox, mononucleosis, cold sores, and genital sores, and are of a particular concern for patients who are immunosuppressed due cancer or AIDS... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 9, 2013 Category: Consumer Health News Tags: Biology / Biochemistry Source Type: news

Drug for cold sores caused by the sun: Pill could block viral particles from multiplying
In a new trial in America, 125 patients will take the drug for seven days after the first signs of a cold sore. The same number will take a placebo. (Source: the Mail online | Health)
Source: the Mail online | Health - August 20, 2013 Category: Consumer Health News Source Type: news

What is urethritis? What causes urethritis?
Urethritis is the inflammation and swelling of the urethra - the narrow tube that carries urine from the bladder out of the body. Urethritis is caused by either a bacterium or a virus - it is classed as either gonococcal urethritis which is caused by Neisseria gonorrhoeae, or non-gonococcal urethritis (NGU), caused by Chlamydia trachomatis - one of the most common sexually transmitted diseases affecting both men and women. The most common viral causes of urethritis are herpes simplex virus and cytomegalovirus... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 20, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Dating After 50: Are Condoms Still Necessary?
The short answer is "yes." The longer answer is more complicated.read more (Source: Psychology Today Sex Center)
Source: Psychology Today Sex Center - August 15, 2013 Category: Sexual Medicine Authors: Michael Castleman, M.A. Tags: Anxiety Health Relationships Sex aarp biblical sense chlamydia cold sores condoms daters genital warts gonorrhea hand massage health officials male lust monogamy older adults public health authorities risk factor sex Source Type: news

Discovery reveals key mechanism responsible for herpes virus
Herpes viruses are like tiny powder kegs waiting to explode. For more than 20 years scientists suspected that herpes viruses were packaged so full of genetic material that they built up an internal pressure so strong it could shoot viral DNA into a host cell during infection. No one had been able to prove that theory until now. Carnegie Mellon University biophysicist Alex Evilevitch together with his graduate student David Bauer and University of Pittsburgh collaborators Fred Homa and Jamie Huffman have measured, for the first time, the pressure inside human herpes simplex virus 1 (HSV-1)... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 26, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Virus discovery: 'blast' mechanism used to infect host
Researchers have discovered the first "pressure-driven infection mechanism" in a human virus, which blasts infectious DNA into cells with pressure eight times higher than that of a typical car tire. The study, published in the Journal of the American Chemical Society, suggests that this discovery could open the door to new treatments for viral infections. Researchers from the US and Sweden analyzed the pressure inside the herpes simplex virus 1 (HSV-1), the infection that causes cold sores... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 26, 2013 Category: Consumer Health News Tags: Genetics Source Type: news

Experimental drug tackles both HIV and genital herpes
Scientists are developing a drug that may be effective in treating two sexually transmitted infections at once - HIV and genital herpes - as well as potentially preventing the spread of HIV from one person to another. Researchers from the University of Leuven (KU Leuven) in Belgium say the experimental drug, dubbed PMEO-DAPym, can tackle both HIV (human immunodeficiency virus) and HSV (herpes simplex virus). The drug can prevent HIV from multiplying, making the cells targeted by the virus less susceptible to infection... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 25, 2013 Category: Consumer Health News Tags: HIV / AIDS Source Type: news

Pressurized virus blasts its infectious DNA into human cells
(American Chemical Society) The virus that causes those painful lip blisters known as cold sores has an internal pressure eight times higher than a car tire, and uses it to literally blast its infectious DNA into human cells, scientists are reporting in a new study. Discovery of the pressure-driven infection mechanism -- the first in a human virus -- opens the door to new treatments for viral infections, they add in a study in the Journal of the American Chemical Society. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 24, 2013 Category: Global & Universal Source Type: news

Carnegie Mellon biophysicist obtains first experimental evidence of pressure inside the herpes virus
(Carnegie Mellon University) Scientists have long suspected that herpes viruses were packaged so full of genetic material that they built up an internal pressure so strong it could shoot viral DNA into a host cell during infection. Carnegie Mellon University and University of Pittsburgh researchers have measured, for the first time, the pressure inside human herpes simplex virus 1. The study, published online in the Journal of the American Chemical Society, establishes a new target for antiviral therapies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 24, 2013 Category: Global & Universal Source Type: news

Immune Response Exploited By Herpes Virus To Bolster Infection
Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an immune system receptor to boost its infectivity and ability to cause disease. The findings are published in the journal Nature Communications. HSV-1 is a persistent and problematic pathogen. Typically, it infects victims through oral secretions (kissing, sharing a contaminated toothbrush) or through openings in the skin... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 11, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Vitamins: stop taking the pills
This article was corrected on 7 June 2013. During editing, a line in the fifth from last paragraph, beginning 'Another example is St John's wort…' was accidentally transposed, leading to the suggestion that serotonin was a medicine rather than a brain chemical.Alternative medicineHealth & wellbeingHealthCancerCancerMedical researchPharmaceuticals industryDepressionguardian.co.uk © 2013 Guardian News and Media Limited or its affiliated companies. All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds     (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - June 7, 2013 Category: Science Tags: The Guardian Depression Pharmaceuticals industry Health Medical research & wellbeing Society Extracts Features Cancer Life and style Alternative medicine Science Source Type: news

Herpes virus exploits immune response to bolster infection
(University of California - San Diego) Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1, which affects an estimated 50 to 80 percent of all American adults, exploits an immune system receptor to boost its infectiousness and ability to cause disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 6, 2013 Category: Global & Universal Source Type: news

Oro-labial Herpes Simplex (“Cold Sores”)
This clustered grouping of small, shallow erosions surmounting a slightly indurated plaque is characteristic for “cold sores.” Because no vesicles were present and the lesions appeared to be crusting over, the patient was advised to apply an OTC cream (docosanol 10%) per package insert instructions. (Source: Consultant Live)
Source: Consultant Live - May 15, 2013 Category: Primary Care Source Type: news

Health advice: cold sores
Britain's leading health and wellbeing experts answer your questions     (Source: Telegraph Health)
Source: Telegraph Health - May 13, 2013 Category: Consumer Health News Source Type: news

Health advice: cold sores
Britain's leading health and wellbeing experts answer your questions     (Source: The Telegraph : Health Advice)
Source: The Telegraph : Health Advice - May 13, 2013 Category: Consumer Health News Source Type: news

Topical Medications Improve Cold Sore OutcomesTopical Medications Improve Cold Sore Outcomes
Find out what topical agents to use within the 24-hour window of opportunity -- for nipping cold sores in the bud. Wounds (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 17, 2013 Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news

Is EBV a Common Cause of Elevated Liver Enzymes?
Discussion Infectious mononucleosis is caused by an Epstein-Barr Virus (EBV) infection causing the triad of fever, sore throat and adenopathy. The differential diagnosis of clinical presentations similar to EBV includes: Viral Cytomegalovirus Herpes simplex Hepatitis A, B, C HIV Varicella Bacterial/Spirochete Brucellosis Leptospirosis Syphilis Q fever Miscellaneous Autoimmune hepatitis Drug side effects Ischemia Wilson Disease Treatment for EBV infections is mainly supportive. Anti-viral medications such as ganciclovir are usually used for severe problems. Liver failure has been treated by transplant. Refraining fr...
Source: PediatricEducation.org - April 1, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

Inhibiting Akt May Be A Useful Therapeutic Strategy For Stopping Herpes Infections
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a novel strategy for preventing infections due to the highly common herpes simplex viruses, the microbes responsible for causing genital herpes (herpes simplex virus 2) and cold sores (herpes simplex virus 1). The finding, published online by The FASEB Journal, could lead to new drugs for treating or suppressing herpes virus infections. "We've essentially identified the molecular "key" that herpes viruses use to penetrate cell membranes and infect cells of the human body," said Betsy Herold, M.D... (Source: Health N...
Source: Health News from Medical News Today - March 28, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Cold Sores Causing Memory Problems?
(Ivanhoe Newswire) – The virus that causes cold sores, along with other viral or bacterial infections, may be associated with cognitive problems. (Source: Medical Headlines From Ivanhoe.com)
Source: Medical Headlines From Ivanhoe.com - March 27, 2013 Category: Consumer Health News Source Type: news

Infection exposure linked to cognitive performance
Research shows that people with the highest level of exposure to common pathogens, such as the cold-sore-causing virus herpes simplex type 1, have worse cognition than those with the lowest level of exposure. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - March 27, 2013 Category: Psychiatry Source Type: news

Infection exposure linked to cognitive performance
Research shows that people with the highest level of exposure to common pathogens, such as the cold-sore-causing virus herpes simplex type 1, have worse cognition than those with the lowest level of exposure. (Source: MedWire News - Infectious Diseases)
Source: MedWire News - Infectious Diseases - March 27, 2013 Category: Infectious Diseases Source Type: news

Cold Sores Could Lead To Increased Cognitive Problems
Elderly adults who have specific infections - like the herpes cold sore virus - may have declined memory abilities and decreased thinking - more so than others in their age group, according to a new study published in Neurology. The researchers discovered that more than 1,600 older adults - those with herpes simplex and other viruses and bacteria achieved lower marks on standard mental skills tests. However, the outcomes do not necessarily mean that the infections are responsible... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 26, 2013 Category: Consumer Health News Tags: Seniors / Aging Source Type: news

Cold sores linked to cognitive decline
The virus causing your cold sore may put you at risk for something more insidious: Lower cognitive abilities. (Source: WDSU.com - Health)
Source: WDSU.com - Health - March 26, 2013 Category: Consumer Health News Source Type: news

Could Herpes Virus Affect Memory in Older Adults?
Chronic infection with cold sores may affect thinking, especially in sedentary folks, study suggests (Source: WebMD Health)
Source: WebMD Health - March 26, 2013 Category: Consumer Health News Source Type: news

Could Herpes Virus Affect Memory in Older Adults?
Chronic infection with cold sores may affect thinking, especially in sedentary folks, study suggests Source: HealthDay Related MedlinePlus Pages: Cold Sores, Memory (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 25, 2013 Category: Consumer Health News Source Type: news

Einstein study reveals new approach for stopping herpes infections
(Albert Einstein College of Medicine) Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a novel strategy for preventing infections due to the highly common herpes simplex viruses, the microbes responsible for causing genital herpes (herpes simplex virus 2) and cold sores (herpes simplex virus 1). The finding, published online by The FASEB Journal, could lead to new drugs for treating or suppressing herpes virus infections. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 25, 2013 Category: Global & Universal Source Type: news

Researchers create map of “shortcuts” between all human genes
Researchers at Rockefeller University, along with colleagues at Necker Hospital for Sick Children and the Pasteur Institute in Paris and Ben-Gurion University in Israel, have generated the full set of distances, routes and degrees of separation between any two human genes, creating a map of gene “shortcuts” that aims to simplify the hunt for disease-causing genes in monogenic diseases. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 18, 2013 Category: Biomedical Science Authors: pubaff Tags: Science News herpes simplex encephalitis human gene connectome Jean-Laurent Casanova Source Type: news

Herpes Simplex Virus Vector Offers Novel Treatment Approach For Bladder Pain
Severe chronic pain associated with conditions such as bladder pain syndrome/interstitial cystitis often require the use of opioid medication, with the risk of dependency and serious adverse reactions. An alternative treatment strategy increases the levels of a naturally occurring painkiller in and around the nerves that deliver pain signals to the bladder. This new therapeutic approach is described in an article in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Human Gene Therapy website... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 18, 2013 Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news

Blocking Immune Response May Enhance Viral Therapy Against Solid Tumors
Following several years of study, investigators have found more evidence that viral therapy to treat solid tumors can be enhanced by blocking the body's natural immune response. Oncolytic viruses have shown promise as anticancer agents, with variations of the herpes simplex virus (HSV) among the most commonly used. However, many studies have shown that the effectiveness of viral therapy to eradicate tumors has not been as successful with patients as it has been in the lab... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 15, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Novel treatment approach for bladder pain using a herpes simplex virus vector reported
(Mary Ann Liebert, Inc./Genetic Engineering News) An exciting new treatment strategy for chronic pain associated with conditions such as bladder pain syndrome/interstitial cystitis is described in an article in Human Gene Therapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 14, 2013 Category: Global & Universal Source Type: news

The Reason Pregnant Women Are More Vulnerable To Certain Infections Is Likely Due To Progesterone
Women who are pregnant or using synthetic progesterone birth control injections have a conspicuous vulnerability to certain infections including malaria, Listeria, HIV, and herpes simplex virus. A new research report appearing in the March 2013 issue of the Journal of Leukocyte Biology offers strong evidence for a possible explanation: the progesterone receptor, a pregnancy hormone sensor, targets a part of the immune system responsible for protection against these and other invaders... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 4, 2013 Category: Consumer Health News Tags: Pregnancy / Obstetrics Source Type: news

Protein Link To STI Susceptibility Discovered
Monash Institute of Medical Research scientists have found a protein in the female reproductive tract that protects against sexually transmitted diseases (STIs) such as chlamydia and herpes simplex virus (HSV). It is estimated that 450 million people worldwide are newly infected with STIs each year. Chlamydia has the highest infection rate of all the STIs reported in Australia... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 3, 2013 Category: Consumer Health News Tags: Sexual Health / STDs Source Type: news

Agenus completes patient enrolment in HSV-2 therapeutic vaccine study
Biotechnology company Agenus has finished enrolling patients in a double-blind, multicentre, randomised Phase II study of its recombinant therapeutic vaccine for the treatment of genital herpes in herpes simplex virus-2 (HSV-2) positive patients. (Source: Drug Development Technology)
Source: Drug Development Technology - March 1, 2013 Category: Pharmaceuticals Source Type: news

Progesterone may be why pregnant women are more vulnerable to certain infections
(Federation of American Societies for Experimental Biology) Women who are pregnant or using synthetic progesterone birth control injections have a vulnerability to infections including malaria, Listeria, HIV, and herpes simplex virus. Research in the Journal of Leukocyte Biology shows that the progesterone receptor, a pregnancy hormone sensor, targets a part of the immune system responsible for protection against these invaders. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 28, 2013 Category: Global & Universal Source Type: news

MIMR researchers find a protein link to STI susceptibility
(Monash Institute of Medical Research) Monash Institute of Medical Research scientists have found a protein in the female reproductive tract that protects against sexually transmitted diseases such as chlamydia and herpes simplex virus. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 28, 2013 Category: Global & Universal Source Type: news

Engineered oncolytic herpes virus inhibits ovarian and breast cancer metastases
A genetically reprogrammed Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, according to a new study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 1, 2013 Category: Science Source Type: news

Engineered oncolytic herpes virus inhibits ovarian and breast cancer metastases
(Public Library of Science) A genetically reprogrammed Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, according to a new study published January 31 in the Open Access journal PLOS Pathogens. The paper reports on the collaborative research from scientists at the at the University of Bologna and specifically describes that the HSV converted into a therapeutic anticancer agent attacks breast and ovarian cancer metastases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 31, 2013 Category: Cancer & Oncology Source Type: news

Most Visited MedlinePlus Health Topics - 2012
MedlinePlus.gov offers over 900 Health Topic pages covering a myriad of diseases, illnesses, health conditions and wellness issues. Millions of users visited our Health Topic pages in 2012. Which were the most visited? Take a look at our list of "Top 10 Most Visited Health Topics of 2012": High Blood Pressure Exercise and Physical Fitness Diabetes Diabetic Diet COPD (Chronic Obstructive Pulmonary Disease) Skin Conditions Autoimmune Diseases Herpes Simplex Herniated Disk Heart Diseases (Source: What's New on MedlinePlus)
Source: What's New on MedlinePlus - January 3, 2013 Category: Consumer Health News Source Type: news