New gene therapy approach eliminates at least 90% latent herpes simplex virus 1
(Fred Hutchinson Cancer Research Center) Infectious disease researchers at Fred Hutchinson Cancer Research Center have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes. In animal models, the findings show at least a 90 percent decrease in the latent virus, enough researchers expect that it will keep the infection from coming back. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 18, 2020 Category: Infectious Diseases Source Type: news
Epidemiology of Herpes Simplex Virus in Europe Transitioning
WEDNESDAY, July 22, 2020 -- The epidemiology of herpes simplex virus (HSV)-1 is transitioning away from oral acquisition in childhood with an increasing proportion of HSV-1 detection in genital herpes, according to a study published online July 16... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 22, 2020 Category: Pharmaceuticals Source Type: news
TREMFYA ® (guselkumab) Approved by U.S. Food and Drug Administration as the First Selective Interleukin (IL)-23 Inhibitor for Active Psoriatic Arthritis
HORSHAM, PA, July 14, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved TREMFYA® (guselkumab) for adult patients with active psoriatic arthritis (PsA), a chronic progressive disease characterized by painful joints and skin inflammation.[1],[2] TREMFYA is the first treatment approved for active PsA that selectively inhibits interleukin (IL)-23, a naturally occurring cytokine that is involved in normal inflammatory and immune responses associated with the symptoms of PsA. The safety and efficacy of TREMFYA in PsA have been dem...
Source: Johnson and Johnson - July 14, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news
Brain model links herpes virus to development of Alzheimer's disease
Bio-engineered models of the human brain infected with herpes simplex virus-1 develop many of the same characteristics found in Alzheimer's disease, according to a new analysis published by Science Advances. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 6, 2020 Category: Consumer Health News Source Type: news
Herpes Virus Yields Up Genetic Secrets
WEDNESDAY, April 29, 2020 -- Herpes simplex virus -- the virus that causes cold sores -- is more complex than scientists had thought, a new study finds.
It had been believed that there were about 80 so-called open reading frames in the herpes gene,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 29, 2020 Category: General Medicine Source Type: news
Herpes virus decoded
(University of W ü rzburg) The genome of the herpes simplex virus 1 was decoded using new methods. Hundreds of previously unknown gene products were found. The virus causes lip herpes, but can also be life-threatening. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 27, 2020 Category: Infectious Diseases Source Type: news
Roche receives FDA approval for cobas HPV test for use on the cobas 6800/8800 Systems to identify women at risk for cervical cancer
Basel, 21 April 2020 - Roche (SIX: RO, ROG; OTCQX:RHHBY) today announced US Food and Drug Administration (FDA) approval for the cobas ® HPV test for use on the fully automated, high-throughput cobas® 6800/8800 Systems. The cobas® HPV test identifies women at risk for cervical cancer by detecting the presence of high-risk human papillomavirus (HPV) DNA in cervical samples. Persistent high-risk HPV infections can develop into pre cancerous lesions and, if left untreated, these lesions can progress to cervical cancer.“The approval of our HPV test for the cobas 6800 and 8800 Systems enables molec...
Source: Roche Media News - April 21, 2020 Category: Pharmaceuticals Source Type: news
Can Vitamin Supplements Prevent Infection? Dr. Mallika Marshall Answers Your Coronavirus Questions
BOSTON (CBS) – As the number of coronavirus cases continues to grow, we are receiving a number of questions from the public. Dr. Mallika Marshall answered some of the questions sent to WBZ-TV’s Facebook, Instagram and Twitter accounts.
I am a recovering cancer patient. Would cancer be considered an underlying condition? – Harry, Hingham
It depends on the type of cancer and where you are in your recovery. But in general, people with cancer are often treated with medications that can weaken their immune system, putting them at greater risk for infection, including the coronavirus. So I would be particularly carefu...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 20, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated Local Coronavirus Dr. Mallika Marshall Source Type: news
Unique new antiviral treatment made using sugar
(University of Manchester) New antiviral materials made from sugar have been developed to destroy viruses on contact and may help in the fight against viral outbreaks. This new development from a collaborative team of international scientists shows promise for the treatment of herpes simplex (cold sore virus), respiratory syncytial virus, hepatitis C, HIV, and Zika virus to name a few. The team have demonstrated success treating a range of viruses in the lab - including respiratory infections to genital herpes. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 29, 2020 Category: Infectious Diseases Source Type: news
Herpes simplex viruses: new relationships between epidemiology and history
(Molecular Biology and Evolution (Oxford University Press)) An Italian research team has refined the history and origins of two extremely common pathogens in human populations, herpes simplex virus type 1 and type 2. Using and applying rather precise data methods they estimated that the circulating strains of herpes simplex virus type 1 migrated from Africa about 5000 years ago. The exit from Africa of herpes simplex virus type 2 was even more recent and probably occurred in the eighteenth century, during the height of the slave trade. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 13, 2020 Category: Infectious Diseases Source Type: news
Herpes's Achilles heel
(Harvard Medical School) Scientists have used the gene-editing tool CRISPR-Cas9 to disrupt both latent reservoirs of the herpes simplex virus and actively replicating virus in human fibroblast cells. Experiments pinpoint weak spot that can make the virus susceptible to gene editing. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 12, 2019 Category: Infectious Diseases Source Type: news
Could a hot 'lipstick' end the misery of cold sores?
A German-engineered device, which is the size and shape of a lipstick, may help those infected with the HSV-1 virus, which causes cold sores. (Source: the Mail online | Health)
Source: the Mail online | Health - December 10, 2019 Category: Consumer Health News Source Type: news
Medical News Today: How dormant herpes springs back to life
Researchers have now uncovered a cellular mechanism that may explain how the herpes simplex virus goes into and comes out of hiding. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 23, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Congenital viral infections in England over five decades: a population-based observational study
Study (data from 1968 to 2016) reports that compared with earlier years of the study, rates in 2016 were higher for congenital cytomegalovirus (CMV), herpes simplex virus, and varicella zoster virus, but lower for rubella. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 20, 2019 Category: Consumer Health News Source Type: news
Medical News Today: Preventing herpes infections: Study offers new insights
A new study reveals a key protein that can encourage or slow the progression of the herpes simplex virus 1 and tests a compound that blocks the virus. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 29, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
