The potential up-regulation risk of 3' UTR SNP (rs10787760 G   & gt;  A) for the VAX1 gene is associated with NSCLP in the northwest Chinese population
Gene. 2024 Apr 10:148458. doi: 10.1016/j.gene.2024.148458. Online ahead of print.ABSTRACTAIMS: To investigate the association between single nucleotide polymorphisms (SNPs) in 3'UTR region of VAX1, SYT14 and PAX7 genes and the risk of non-syndromic cleft palate (NSCLP) in a northwest Chinese population.MAIN METHODS: A case-control study was conducted in 406 normal controls and 399 NSCLP patients. Using iMLDRTM genotyping technology, eight SNPs of three genes ((rs10787760, rs7086344 at VAX1), (rs1010113, rs851114, and rs485874 at PAX7), and (rs61820397, rs4609425, rs12133399 at SYT14)) were genotyped to investigate the diff...
Source: Gene - April 12, 2024 Category: Genetics & Stem Cells Authors: Huan Feng Bing Wei Xiaodong Xie Peiqiang Li Xi Shen Source Type: research

Evaluation of Vermillion Symmetry and Scar Quality in Unilateral Cleft Lip Repair Using Modified Millard ’s Technique Versus Fisher’s Technique
Since the primary goal of cleft lip repair is to achieve a symmetrical, aesthetic lip, several surgical techniques have been utilized. Accordingly, in this study, a unilateral cleft lip was surgically repaired using two techniques: modified Millard's and Fisher's techniques. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - April 11, 2024 Category: ENT & OMF Authors: Mohamed Salah Alwadeai, Mamdouh Ahmed Aboul Hassan, Leena Al-aroomy, Ahlam Abdulsalam Othman, Mostafa Ibrahim Shindy, Safaa Baz Source Type: research

Respiratory outcomes after cleft palate closure in Robin sequence: a retrospective study
ConclusionsThe possible risk factors for these outcomes were a low preoperative weight and history of TLA. Closer postoperative surveillance should be considered for patients with these risk factors.Clinical relevanceIdentifying risk factors for respiratory complications could provide clinicians better insight into their patients and allows them to provide optimal care for their patients. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 11, 2024 Category: Dentistry Source Type: research

Design and fabrication of silicone cleft lip simulation model for personalized surgical training
To elucidate the design and fabrication methodologies employed in creating a personalized cleft lip simulation model, primarily intended for enhancing surgical training and diverse applications. The research further seeks to assess the viability of integrating this simulation model into undergraduate oral experiments and instructional settings. (Source: Journal of Plastic, Reconstructive and Aesthetic Surgery)
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - April 11, 2024 Category: Cosmetic Surgery Authors: Yaqi Chen, Ming Li, Yong Wu, Lidong Wang, Qingying Cui Source Type: research

A Conceptual Thematic Framework of Psychological Adjustment in Caregivers of Children with Craniofacial Microsomia
CONCLUSIONS: Narrative interviews provided rich insight into caregivers' experiences of having a child with CFM and enabled the development of a conceptual thematic framework to guide clinical care and future research. Information gathered from this study demonstrates the need to incorporate evidence-based psychological support for families into the CFM pathway from birth onward.PMID:38584503 | DOI:10.1177/10556656241245284 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - April 8, 2024 Category: ENT & OMF Authors: Nicola M Stock Bruna Costa Jade Parnell Alexis L Johns Canice E Crerand Kristin Billaud Feragen Laura P Stueckle Angela Mills Leanne Magee Matthew Hotton Melissa Tumblin Amy Schefer Amelia F Drake Carrie L Heike Source Type: research

A Conceptual Thematic Framework of Psychological Adjustment in Caregivers of Children with Craniofacial Microsomia
CONCLUSIONS: Narrative interviews provided rich insight into caregivers' experiences of having a child with CFM and enabled the development of a conceptual thematic framework to guide clinical care and future research. Information gathered from this study demonstrates the need to incorporate evidence-based psychological support for families into the CFM pathway from birth onward.PMID:38584503 | DOI:10.1177/10556656241245284 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - April 8, 2024 Category: ENT & OMF Authors: Nicola M Stock Bruna Costa Jade Parnell Alexis L Johns Canice E Crerand Kristin Billaud Feragen Laura P Stueckle Angela Mills Leanne Magee Matthew Hotton Melissa Tumblin Amy Schefer Amelia F Drake Carrie L Heike Source Type: research

A Conceptual Thematic Framework of Psychological Adjustment in Caregivers of Children with Craniofacial Microsomia
CONCLUSIONS: Narrative interviews provided rich insight into caregivers' experiences of having a child with CFM and enabled the development of a conceptual thematic framework to guide clinical care and future research. Information gathered from this study demonstrates the need to incorporate evidence-based psychological support for families into the CFM pathway from birth onward.PMID:38584503 | DOI:10.1177/10556656241245284 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - April 8, 2024 Category: ENT & OMF Authors: Nicola M Stock Bruna Costa Jade Parnell Alexis L Johns Canice E Crerand Kristin Billaud Feragen Laura P Stueckle Angela Mills Leanne Magee Matthew Hotton Melissa Tumblin Amy Schefer Amelia F Drake Carrie L Heike Source Type: research

A Conceptual Thematic Framework of Psychological Adjustment in Caregivers of Children with Craniofacial Microsomia
CONCLUSIONS: Narrative interviews provided rich insight into caregivers' experiences of having a child with CFM and enabled the development of a conceptual thematic framework to guide clinical care and future research. Information gathered from this study demonstrates the need to incorporate evidence-based psychological support for families into the CFM pathway from birth onward.PMID:38584503 | DOI:10.1177/10556656241245284 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - April 8, 2024 Category: ENT & OMF Authors: Nicola M Stock Bruna Costa Jade Parnell Alexis L Johns Canice E Crerand Kristin Billaud Feragen Laura P Stueckle Angela Mills Leanne Magee Matthew Hotton Melissa Tumblin Amy Schefer Amelia F Drake Carrie L Heike Source Type: research

A Conceptual Thematic Framework of Psychological Adjustment in Caregivers of Children with Craniofacial Microsomia
CONCLUSIONS: Narrative interviews provided rich insight into caregivers' experiences of having a child with CFM and enabled the development of a conceptual thematic framework to guide clinical care and future research. Information gathered from this study demonstrates the need to incorporate evidence-based psychological support for families into the CFM pathway from birth onward.PMID:38584503 | DOI:10.1177/10556656241245284 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - April 8, 2024 Category: ENT & OMF Authors: Nicola M Stock Bruna Costa Jade Parnell Alexis L Johns Canice E Crerand Kristin Billaud Feragen Laura P Stueckle Angela Mills Leanne Magee Matthew Hotton Melissa Tumblin Amy Schefer Amelia F Drake Carrie L Heike Source Type: research

A Conceptual Thematic Framework of Psychological Adjustment in Caregivers of Children with Craniofacial Microsomia
CONCLUSIONS: Narrative interviews provided rich insight into caregivers' experiences of having a child with CFM and enabled the development of a conceptual thematic framework to guide clinical care and future research. Information gathered from this study demonstrates the need to incorporate evidence-based psychological support for families into the CFM pathway from birth onward.PMID:38584503 | DOI:10.1177/10556656241245284 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - April 8, 2024 Category: ENT & OMF Authors: Nicola M Stock Bruna Costa Jade Parnell Alexis L Johns Canice E Crerand Kristin Billaud Feragen Laura P Stueckle Angela Mills Leanne Magee Matthew Hotton Melissa Tumblin Amy Schefer Amelia F Drake Carrie L Heike Source Type: research

A Conceptual Thematic Framework of Psychological Adjustment in Caregivers of Children with Craniofacial Microsomia
CONCLUSIONS: Narrative interviews provided rich insight into caregivers' experiences of having a child with CFM and enabled the development of a conceptual thematic framework to guide clinical care and future research. Information gathered from this study demonstrates the need to incorporate evidence-based psychological support for families into the CFM pathway from birth onward.PMID:38584503 | DOI:10.1177/10556656241245284 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - April 8, 2024 Category: ENT & OMF Authors: Nicola M Stock Bruna Costa Jade Parnell Alexis L Johns Canice E Crerand Kristin Billaud Feragen Laura P Stueckle Angela Mills Leanne Magee Matthew Hotton Melissa Tumblin Amy Schefer Amelia F Drake Carrie L Heike Source Type: research

A Conceptual Thematic Framework of Psychological Adjustment in Caregivers of Children with Craniofacial Microsomia
CONCLUSIONS: Narrative interviews provided rich insight into caregivers' experiences of having a child with CFM and enabled the development of a conceptual thematic framework to guide clinical care and future research. Information gathered from this study demonstrates the need to incorporate evidence-based psychological support for families into the CFM pathway from birth onward.PMID:38584503 | DOI:10.1177/10556656241245284 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - April 8, 2024 Category: ENT & OMF Authors: Nicola M Stock Bruna Costa Jade Parnell Alexis L Johns Canice E Crerand Kristin Billaud Feragen Laura P Stueckle Angela Mills Leanne Magee Matthew Hotton Melissa Tumblin Amy Schefer Amelia F Drake Carrie L Heike Source Type: research

Characterization of the oral microbiota and the relationship of the oral microbiota with the dental and periodontal status in children and adolescents with nonsyndromic cleft lip and palate. Systematic literature review and meta-analysis
ConclusionIn the microbiota, there was a great diversity of microorganisms that can vary according to the type of fissure and surgical interventions predisposing patients to a greater probability of dental caries, it is important to take into account the technique used to describe the oral microbiota in order to be able to compare the different studies.Clinical relevanceStudying the microbiota and the relationship of dental caries and periodontal status in children and adolescents with cleft lip and palate can facilitate the comprehensive care of patients with these conditions. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 8, 2024 Category: Dentistry Source Type: research

Timing of Alveolar Bone Graft and Barriers to Care
CONCLUSION: Patients with public insurance are approximately 3.75 times more likely to receive ABG during permanent dentition. Multidisciplinary teams should work closely with patients on public insurance to ensure timely delivery of ABG.Level of Evidence III, Retrospective.PMID:38576319 | DOI:10.1177/10556656241242695 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - April 5, 2024 Category: ENT & OMF Authors: Elizabeth E Bushong Darin Patmon Hanna Pfershy Cuyler Huffman Anna Carlson John Girotto Source Type: research

Timing of Alveolar Bone Graft and Barriers to Care
CONCLUSION: Patients with public insurance are approximately 3.75 times more likely to receive ABG during permanent dentition. Multidisciplinary teams should work closely with patients on public insurance to ensure timely delivery of ABG.Level of Evidence III, Retrospective.PMID:38576319 | DOI:10.1177/10556656241242695 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - April 5, 2024 Category: ENT & OMF Authors: Elizabeth E Bushong Darin Patmon Hanna Pfershy Cuyler Huffman Anna Carlson John Girotto Source Type: research