Unilateral Cleft Lip Repair With an Asymmetric Z-plasty Unilateral Cleft Lip Repair With an Asymmetric Z-plasty
A unique modification of the classic Z-plasty for cleft lip repair is described here.ePlasty, Open Access Journal of Plastic Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 27, 2018 Category: Consumer Health News Tags: Plastic Surgery & Aesthetic Medicine Journal Article Source Type: news

Venezuela toddler with 'crown on her head' reaches third birthday
Helianny, from San Cristobal, Venezuela, was born with a brain, eyes and nose that failed to form properly in the womb, as well as her suffering a cleft lip, clubbed foot and fused fingers. (Source: the Mail online | Health)
Source: the Mail online | Health - June 11, 2018 Category: Consumer Health News Source Type: news

Toddler whose parents were advised to terminate the pregnancy is approaching her third birthday
Helianny, from San Cristobal, Venezuela, was born with a brain, eyes and nose that failed to form properly in the womb, as well as her suffering a cleft lip, clubbed foot and fused fingers. (Source: the Mail online | Health)
Source: the Mail online | Health - June 11, 2018 Category: Consumer Health News Source Type: news

What is the Developmental Outcomes of Patients with 22q11 Deletion Sequence?
Discussion 22q11.2 deletion sequence (22q11) is the most common micro-deletion syndrome. Most deletions are de novo. It affects ~1 in 2000-4000 live births. As it is autosomal, it affects males and females equally. Childhood mortality is low and often associated with congenital heart defects. Its phenotypic expression is highly variable. Some of the most common medical problems are: Congenital heart defects especially conotruncal abnormalities Palatal problems especially velopharyngeal incompetence and/or cleft lip/palate Immunodeficiency especially T-cell lymphopenia, but also abnormalities of IgG production, autoimmu...
Source: PediatricEducation.org - June 11, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Sheffield student with cleft lip bullied for the way he looked
A 13-year-old boy bullied because of his cleft lip is working with a charity to help others like him. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - May 25, 2018 Category: Consumer Health News Source Type: news

Woman born with a cleft palate reveals stunning transformation
Laura Hawkes, 25, from West Sussex, was days old when she had her first surgery. After being bullied at school about her 'squashed' nose, Laura's face has been transformed via operations. (Source: the Mail online | Health)
Source: the Mail online | Health - May 16, 2018 Category: Consumer Health News Source Type: news

Christian Buchanan was born with no eyes
WARNING: GRAPHIC CONTENT Christian Buchanan, six, from Woodbury, Tennessee, suffers from Tessier cleft lip and palate, which has just 60 known cases in medical history. (Source: the Mail online | Health)
Source: the Mail online | Health - March 8, 2018 Category: Consumer Health News Source Type: news

Six-year-old boy was born with no eyes
WARNING: GRAPHIC CONTENT Christian Buchanan, six, from Woodbury, Tennessee, suffers from Tessier cleft lip and palate, which has just 60 known cases in medical history. (Source: the Mail online | Health)
Source: the Mail online | Health - March 8, 2018 Category: Consumer Health News Source Type: news

Kenya:How Partnerships Are Helping Cleft Lip and Palate Surgeries in Kenya
[The Conversation Africa] About 6% of all children worldwide are born with a birth defect. More than 300 000 babies with birth defects die annually within a month of being born. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 15, 2018 Category: African Health Source Type: news

More proof prescriptions and pregnancy don’t mix: Epilepsy drug found to affect fetal development, causing cleft palate
(Natural News) In the last 10 years, topiramate, an anti-epileptic drug, has been increasingly prescribed to prevent seizures. It is also used to treat bipolar disorder and migraine headaches. Topiramate is also an ingredient for a weight-loss drug that was recently approved by the Food and Drug Administration (FDA). Earlier studies have determined that women who took topiramate... (Source: NaturalNews.com)
Source: NaturalNews.com - January 4, 2018 Category: Consumer Health News Source Type: news

Topiramate in early pregnancy increases risk of oral clefts
Risk of cleft lip or cleft palate is greater if mother takes a higher dose of the drug Related items fromOnMedica Adverse pregnancy outcomes far more likely in epilepsy Study reveals mental cost of epilepsy in pregnancy Cannabis derivative cannabidiol reduces seizures in severe epilepsy disorder New guidelines on epilepsy in pregnancy Epilepsy drug linked to 4,000 birth defects in France (Source: OnMedica Latest News)
Source: OnMedica Latest News - January 2, 2018 Category: UK Health Source Type: news

Risk of Oral Clefts with Topiramate May Be Dose-Dependent (CME/CE)
(MedPage Today) -- Higher doses tied to higher risk of cleft lip, palate (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - December 30, 2017 Category: Neurology Source Type: news

Epilepsy Drug Could Raise Birth Defect Risks
Researchers found that pregnant women with epilepsy who take the drug topiramate during their first trimester  may boost the risk that their child will be born with a cleft lip or cleft palate. (Source: WebMD Health)
Source: WebMD Health - December 27, 2017 Category: Consumer Health News Source Type: news

Does dosing of drug for mom make a difference for baby's risk of cleft lip, palate?
(American Academy of Neurology) Taking a higher dose of topiramate during the first three months of pregnancy may increase a baby's risk of cleft lip or cleft palate more than when taking a lower dose, according to a study published in the Dec. 27, 2017, online issue of Neurology ® , the medical journal of the American Academy of Neurology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 27, 2017 Category: International Medicine & Public Health Source Type: news

Topiramate in Early Pregnancy Increases Risk of Oral Clefts
Study finds that taking a higher dose of the drug in the first trimester increases risk of cleft lip or cleft palate more than taking a lower dose. (Source: BWH for Journalists)
Source: BWH for Journalists - December 27, 2017 Category: Research Source Type: news

Bryan Aves obituary
My father, Bryan Aves, who has died aged 92, established a successful career as a radiographer and radiotherapist despite having left school at 14 without qualifications. At one point he worked as an assistant for the physicistsOtto Frisch andJoseph Rotblat in the secret “tube alloys” experiments that led to the creation of the atom bomb, apparently without knowing what the project was about.Born in Brixton, south London, to Arthur, an accounts clerk for a dog biscuit factory, and Ellen (nee Stallard), a cleaner, Bryan had a cleft palate at birth; reconstructive surgery was not undertaken until he was 13. Becau...
Source: Guardian Unlimited Science - December 21, 2017 Category: Science Authors: Simon Aves Tags: Physics Cancer research Medicine Source Type: news

Exposure to air pollution just before or after conception raises risk of birth defects
(Cincinnati Children's Hospital Medical Center) Women exposed to air pollution just prior to conception or during the first month of pregnancy face an increased risk of their children being born with birth defects, such as cleft lip or palate or abnormal hearts. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 11, 2017 Category: International Medicine & Public Health Source Type: news

Saucier baby needs surgery every six months until she's 18
Eight-month-old Zoey Tidwell, from Saucier in Mississippi, battles an array of complications including undergrown facial bones, a large cleft palate and breathing difficulties. (Source: the Mail online | Health)
Source: the Mail online | Health - November 30, 2017 Category: Consumer Health News Source Type: news

Text-message ‘ Blast ’ Can Expand Access to Surgical Services Text-message ‘ Blast ’ Can Expand Access to Surgical Services
Dozens of patients in Zimbabwe undergoing cleft lip and palate surgery had first learned about the opportunity from an SMS text to their phones, a small study found.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 28, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Text-message ‘blast’ can expand access to surgical services
(Reuters Health) - Dozens of patients in Zimbabwe undergoing cleft lip and palate surgery had first learned about the opportunity from an SMS text to their phones, a small study found. (Source: Reuters: Health)
Source: Reuters: Health - November 27, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Vaping while pregnant causes facial birth defects
Vaping while pregnant can cause cleft palate and other head and facial birth defects, researchers from Virginia Commonwealth University have discovered. Fruity and rich e-liquids are particularly dangerous. (Source: the Mail online | Health)
Source: the Mail online | Health - November 16, 2017 Category: Consumer Health News Source Type: news

Indian man had a moustache transplant to hide cleft lip
The 21-year-old, known as Suresh, from Goa, had surgery to fix his cleft lip, but was left with a scar and a gap. The clip shows surgeon implanting hair from the back and the sides of the head. (Source: the Mail online | Health)
Source: the Mail online | Health - November 1, 2017 Category: Consumer Health News Source Type: news

How to Cope with Emotional Body Issues: Bloat, Belly Fat and More
“You are more than your thoughts, your body, or your feelings. You are a swirling vortex of limitless potential who is here to shake things up and create something new that the universe has never seen.” – Richard Bartlett It’s always tough to look in the mirror and dislike what you see. Whether you’re unhappy with how you look because of unsightly and uncomfortable bloat, belly fat that just won’t go away no matter how much you exercise, flabby arms, cellulite on your legs, a nose that’s too long, wide or misshapen, Rosacea, acne, breasts too small or too large or any other emotion...
Source: Psych Central - November 1, 2017 Category: Psychiatry Authors: Suzanne Kane Tags: Addictions Diet & Nutrition Eating Disorders Healthy Living Self-Esteem belly fat bloat Body Acceptance Body Dissatisfaction Body Dysmorphia dieting Source Type: news

Centralised care needs to be improved to ensure children with cleft lip and palate have best outcomes
Around 1,000 children are born with cleft lip and/or palate in the UK each year, with many children requiring long-term multi-disciplinary care. A University of Bristol study, which assessed whether the centralisation of cleft lip and palate care services improved child outcomes, 15 years after centralisation took place, is published. The study found centralisation has improved patient outcomes but highlights more work is needed in some areas. (Source: University of Bristol news)
Source: University of Bristol news - October 30, 2017 Category: Universities & Medical Training Tags: Health, Research; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School, Faculty of Health Sciences, Bristol Dental School, Institutes, Elizabeth Blackwell; Press Release Source Type: news

Courtney ’s story: Piecing together a genetic puzzle
Courtney Whitmore was born 22 years ago with a cleft palate, two clubbed feet and fists that were so tightly clenched they couldn’t be pulled apart. Since Courtney was an otherwise happy and healthy baby, neither her parents nor her doctor saw cause to be concerned about these seemingly unrelated conditions. What they didn’t realize was that these were the first clues to a genetic puzzle that would take ten years to unravel. The next clue came at age 3. “One day my dad and I were playing peekaboo, and suddenly I couldn’t see,” says Courtney. “My parents rushed me to the hospital and the ...
Source: Thrive, Children's Hospital Boston - October 25, 2017 Category: Pediatrics Authors: Ellen Greenlaw Tags: Diseases & Conditions Our Patients’ Stories brain aneurysm Cardiovascular Genetics Program Cerebrovascular Surgery and Interventions Center Dr. Darren Orbach Dr. Lawrence Karlin Dr. Pedro del Nido Dr. Ronald Lacro Loeys-Dietz syndrome Source Type: news

Cleft palate charity under fire for insensitive letters
The cleft palate charity Kylie Jenner partners with sent out letters saying that children with the condition live out nightmares everyday and comparing them to children in Halloween costumes. (Source: the Mail online | Health)
Source: the Mail online | Health - October 18, 2017 Category: Consumer Health News Source Type: news

Nigeria:How Fever in Early Pregnancy Induces Heart, Facial Birth Defects
[Guardian] Researchers have known for decades that fevers in the first trimester of pregnancy increase risk for some heart defects and facial deformities such as cleft lip or palate. Exactly how this happens is unclear. Scientists have debated whether a virus or other infection source causes the defects, or if fever alone is the underlying problem. (Source: AllAfrica News: Pregnancy and Childbirth)
Source: AllAfrica News: Pregnancy and Childbirth - October 17, 2017 Category: OBGYN Source Type: news

How fever in early pregnancy causes heart, facial birth defects
(Duke University Medical Center) Researchers have known for decades that fevers in the first trimester of pregnancy increase risk for some heart defects and facial deformities such as cleft lip or palate. Exactly how this happens is unclear. Scientists have debated whether a virus or other infection source causes the defects, or if fever alone is the underlying problem. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 10, 2017 Category: Infectious Diseases Source Type: news

Anxiety, depression greatest in younger kids with facial birth defects
(Reuters Health) - Elementary school children with cleft lip, cleft palate and other facial anomalies may struggle more than older kids with anger, anxiety, depression and stress, according to a recent study. (Source: Reuters: Health)
Source: Reuters: Health - October 6, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

NIDCR Science News
Having trouble viewing this email? View it as a Web page.  Mid-Career Funding Helps Scientists Answer Big QuestionsNIDCR’s SOAR grants enable in-depth exploration of oral cancer and tooth regenerationNIDCR • September 28, 2017​​  UofL Researcher Receives Nearly $2 Million Grant to Study Periodontal Disease​  University of Louisville • September 18, 2017​ In-Utero Treatment Reverses Cleft Palate in Mice University of Utah • September 1...
Source: NIDCR Science News - September 29, 2017 Category: Dentistry Source Type: news

Children with craniofacial defects face most difficult social pressures in elementary school
UCLA HealthDr. Justine LeeFINDINGSUCLA researchers  found that elementary school children with craniofacial anomalies show the highest levels of anxiety, depression and difficulties in peer interactions when compared to youths with craniofacial defects in middle and high schools.The findings suggest that keeping a close watch for these signs and educating the child ’s peers about their condition may be necessary for this age group.BACKGROUNDChildren born with congenital craniofacial anomalies, such as cleft lip and cleft palate, may have difficulty socializing with their peers and others and may face bullyi...
Source: UCLA Newsroom: Health Sciences - September 28, 2017 Category: Universities & Medical Training Source Type: news

Tiny diamonds could become best friends to youths with cleft palates
This study showed that our method has a contained, targeted and sustained effect, so we’re very excited about it,” Hong said.Previous experiments showed nanodiamonds to be safe within the body and to be excreted normally. Similarly, earlier work demonstrated that enzymes break down hydrogel.The researchers plan to continue laboratory studies and hope to bring their treatment to clinical trials. Their approach has implications for treating other craniofacial conditions and sleep apnea, as well as healing wounds and bone injuries.Other authors of the study were Dong-Keun Lee, Lawrence Lin, Hsin Chuan Pan, Deborah...
Source: UCLA Newsroom: Health Sciences - September 22, 2017 Category: Universities & Medical Training Source Type: news

Cleft palate cure given to children in-utero is looming
A research team at the University of Utah discovered a cure for cleft palates that worked successfully on mice. The researchers are hopeful that a cure for humans will soon be available. (Source: the Mail online | Health)
Source: the Mail online | Health - September 20, 2017 Category: Consumer Health News Source Type: news

JDR special issue on orofacial clefting and dental and craniofacial anomalies
(International& American Associations for Dental Research) The International and American Associations for Dental Research (IADR/AADR) have published a special issue in the Journal of Dental Research (JDR) on orofacial clefting and dental and craniofacial anomalies. Topics in this special issue range from tooth number and root formation, human and animal genetic studies on orofacial clefting, reviews that prioritize the variants most likely to cause disease, the pathways required for palatogenesis, experimental articles on the periderm and drug therapy articles that rescue cleft palate in mutant mice. (Source: EurekAle...
Source: EurekAlert! - Medicine and Health - September 20, 2017 Category: International Medicine & Public Health Source Type: news

In-utero treatment reverses cleft palate in mice
(University of Utah Health) Researchers at University of Utah Health clarified a molecular pathway responsible for the formation of cleft palate and identified a new treatment to reverse this defect in mouse pups in utero. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 13, 2017 Category: International Medicine & Public Health Source Type: news

Meet the children at the heart of Kylie's charity project
Kylie Jenner partnered with Smile Train, an organization that provides free cleft palate surgeries to children in developing countries. The surgeries are helping these children have higher self esteem. (Source: the Mail online | Health)
Source: the Mail online | Health - September 12, 2017 Category: Consumer Health News Source Type: news

FDA Drug Safety Communication: Risk of oral clefts in children born to mothers taking Topamax (topiramate)
[03-04-2011] The U.S. Food and Drug Administration (FDA) is informing the public of new data that show that there is an increased risk for the development of cleft lip and/or cleft palate (oral clefts) in infants born to women treated with Topamax (topiramate) during pregnancy. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 4, 2017 Category: Drugs & Pharmacology Source Type: news

Zimbabwe: Schweppes Partner Alliance for Smiles to Offer Free Cleft Lip Surgery
[263Chat] Schweppes Holdings Africa Limited in July, partnered Alliance for Smiles (AfS) to offer free cleft lip and palate surgical operations to over 80 patients at Chitungwiza Central Hospital. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 3, 2017 Category: African Health Source Type: news

Six tips for talking with your child about cleft lip or palate
Having a facial difference such as cleft lip or palate can be difficult for any child, but it’s especially challenging when they’re about to enter a new social situation like going to school. For some parents, this time is even more stressful than it is for children. In fact, many of the parents whom I meet in the Cleft and Craniofacial Center at Boston Children’s Hospital tell me that having discussions with their child about the cleft is the number-one concern.  Ideally, you’ll start talking with your child about school or other social situations well in advance. Remember, family is our first...
Source: Thrive, Children's Hospital Boston - July 26, 2017 Category: Pediatrics Authors: Amanda Lasssiter Tags: Ask the Expert Diseases & Conditions Amanda Lassiter back to school health Cleft and Craniofacial Center cleft lip and palate Source Type: news

Zimbabwe: 27 Receive Cleft Lip and Palate Surgery
[The Herald] Twenty -Seven people had undergone cleft lip and palate surgeries at Chitungwiza Central Hospital as of Thursday, while 105 others had been screened. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 25, 2017 Category: African Health Source Type: news

Taking my own advice: When the professional becomes a parent
As a disability expert, my whole career has been spent giving parents advice. I’ve given advice on parenting, doctors, child development, school and resources to support them. I was confident working with families and helping them navigate the often crazy and overwhelming world of special needs. But when I was 34 weeks pregnant with my own child, I found myself on the other side of the situation. My husband and I learned that our son, Jack, would be born with a cleft palate and micrognathia, or an undeveloped lower jaw. The extent of these facial differences wouldn’t be known until he was born. We met with doct...
Source: Thrive, Children's Hospital Boston - July 20, 2017 Category: Pediatrics Authors: Jennifer Ryan Tags: Diseases & Conditions Our Patients’ Stories Cleft and Craniofacial Center cleft lip and palate Dr. Carolyn Rogers Dr. Cory Resnick Pierre Robin sequence Source Type: news

Understanding genetic synergy in cleft palate
(Children's National Health System) Like mechanics fixing a faulty engine, Youssef A. Kousa, M.S., D.O., Ph.D., says researchers will not be able to remedy problems related to IRF6, a gene implicated in cleft palate, until they better understand how the gene works. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 19, 2017 Category: Biology Source Type: news

Getting and giving support for cleft lip and palate
Jack Dolan came into the world with a laugh. His mother, Erin, was mid-chuckle during labor when he was born — “a really joyful entrance,” she says. Looking down at her new son, she and her husband, Jimmy, breathed sighs of relief. “We took one look at him and thought, ‘He’s beautiful,’” she remembers. “We knew then that everything was going to be okay.” It was a happy celebration after a pregnancy sometimes marked by stress and anxiety. During ultrasonography, Erin and Jimmy had learned that Jack would be born with a bilateral cleft lip and palate. Erin, a nurse ...
Source: Thrive, Children's Hospital Boston - July 13, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Cleft and Craniofacial Center cleft lip and palate Dr. John Mulliken Olivia Oppel Source Type: news

Expert insight on cleft lip and palate
Learning that your baby has a cleft lip or palate can be upsetting, but these birth defects are quite common. They occur early in pregnancy when tissue from each side of the head grows together to form the face. If these tissues don’t completely join, the result is a cleft, or gap, on one or both sides of the upper lip. A cleft palate occurs when the tissue that forms the roof of the mouth doesn’t fully come together, leaving an opening between the mouth and nose. It’s not clear what causes a cleft lip or palate, but a combination of genetic and environmental risk factors appears to be involved. “Al...
Source: Thrive, Children's Hospital Boston - July 6, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Ask the Expert Diseases & Conditions Cleft and Craniofacial Center cleft lip Cleft lip and Palate Program cleft palate Dr. Ingrid Ganske Source Type: news

Photos of little boy with cleft palate's first smiles
In April, Charlotte Halliday, 23, from Queensland, shared the story of her then newborn son Charlie who was born with a severe cleft palate and lip. (Source: the Mail online | Health)
Source: the Mail online | Health - July 5, 2017 Category: Consumer Health News Source Type: news

2 Chapel Hill-based nonprofits to merge
Chapel Hill-based nonprofits The American Cleft Palate-Craniofacial Association (ACPA) and the Cleft Palate Foundation (CPF) will merge effective June 30. The combination comes at a time when “nonprofits are being asked to do more with less,” says Wendy-Jo Toyama, who will serve as executive director of the combined entity. Combined, the organizations will have an operating budget of about $1.5 million, she says. It’s about eliminating redund ancies – for instance, developing two budgets,… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - June 29, 2017 Category: Pharmaceuticals Authors: Jennifer Henderson Source Type: news

Zimbabwe: Free Screening for Cleft Palate Begins
[The Herald] The screening for cleft lip and palate surgical operations set to benefit 60 patients started at Parirenyatwa Hospital on Sunday, where scores of patients turned up for surgeries which started yesterday and expected to last until Saturday. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 20, 2017 Category: African Health Source Type: news

Epigenetics could help diagnose different types of cleft
Cleft lip and/or palate are common birth defects and affect around 15 in every 10,000 births in Europe. New research by the University of Bristol from the largest study of cleft lip and/or palate in the world, the Cleft Collective, has found epigenetics could help diagnose different types of cleft. (Source: University of Bristol news)
Source: University of Bristol news - June 14, 2017 Category: Universities & Medical Training Tags: International, Health, Research; Faculty of Health Sciences, Faculty of Health Sciences, School of Oral and Dental Sciences, Faculty of Health Sciences, Bristol Medical School; Press Release Source Type: news

Model With Rare Genetic Disorder Is A Brilliant Example Of Inclusion
This world is a diverse one, so it’s refreshing when the fashion industry reflects that reality. And Seattle-based model Melanie Gaydos is hoping to add to that effort. Gaydos, 28, was born with ectodermal dysplasia, a genetic disorder that can interfere with the proper growth of the hair, nails, teeth, skin and glands. Her involvement in the fashion community is helping people like her to see a place for them in the highly stylized world of modeling. A post shared by Melanie Gaydos (@melaniegaydos) on May 17, 2017 at 5:12pm PDT Fewer than 200,000 people in the United States experience the rare condition,&...
Source: Healthy Living - The Huffington Post - June 8, 2017 Category: Consumer Health News Source Type: news