Clinical Features and Survival Outcomes in Children and Adolescents With Malignant Mediastinal Germ Cell Tumors Based on Surveillance, Epidemiology, and End Results Database Analysis
CONCLUSIONS: Our population-based evidence showed that MMGCT had worse prognosis in older children and adolescents. Choriocarcinomas and embryonal carcinomas had the worst prognosis. Surgery can prolong survival time. Chemotherapy and radiotherapy were not associated with improved prognosis.PMID:37062232 | DOI:10.1016/j.jss.2023.03.018 (Source: Cell Research)
Source: Cell Research - April 16, 2023 Category: Cytology Authors: Peng Wu Yicheng Yang Zhechen Yu Lingling Zhao Shaoguang Feng Source Type: research

Gestational and Non-gestational Trophoblastic Neoplasia. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No.  032/049, April 2022)
Geburtshilfe Frauenheilkd. 2023 Mar 9;83(3):267-288. doi: 10.1055/a-1904-6461. eCollection 2023 Mar.ABSTRACTPurpose The aim was to develop and update a guideline which would improve the quality of care offered to women with gestational and non-gestational trophoblastic disease, a group of diseases characterized by their rarity and biological heterogeneity. Methods In accordance with the method used to compile S2k-guidelines, the guideline authors carried out a search of the literature (MEDLINE) for the period 1/2020 to 12/2021 and evaluated the recent literature. No key questions were formulated. No structured literature s...
Source: Geburtshilfe und Frauenheilkunde - April 6, 2023 Category: OBGYN Authors: Clemens Tempfer Lars-Christian Horn Sven Ackermann Ralf Dittrich Jens Einenkel Andreas G ünthert Heidemarie Haase J ürgen Kratzsch Michael Krei ßl Stephan Polterauer Andreas Ebert Eric Steiner Falk Thiel Michael Eichbaum Tanja Fehm Martin C Koch Paul G Source Type: research

Gestational and Non-gestational Trophoblastic Neoplasia. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No.  032/049, April 2022)
Geburtshilfe Frauenheilkd. 2023 Mar 9;83(3):267-288. doi: 10.1055/a-1904-6461. eCollection 2023 Mar.ABSTRACTPurpose The aim was to develop and update a guideline which would improve the quality of care offered to women with gestational and non-gestational trophoblastic disease, a group of diseases characterized by their rarity and biological heterogeneity. Methods In accordance with the method used to compile S2k-guidelines, the guideline authors carried out a search of the literature (MEDLINE) for the period 1/2020 to 12/2021 and evaluated the recent literature. No key questions were formulated. No structured literature s...
Source: Nuklearmedizin - April 6, 2023 Category: Radiology Authors: Clemens Tempfer Lars-Christian Horn Sven Ackermann Ralf Dittrich Jens Einenkel Andreas G ünthert Heidemarie Haase J ürgen Kratzsch Michael Krei ßl Stephan Polterauer Andreas Ebert Eric Steiner Falk Thiel Michael Eichbaum Tanja Fehm Martin C Koch Paul G Source Type: research