Efficacy of a Herbal Formulation Based on Foeniculum Vulgare in Oligo/Amenorrhea: A Randomized Clinical Trial.
CONCLUSION: Fomentex herbal tea is a safe, well-tolerated, and effective choice in inducing bleeding and maintaining regular bleeding in women with oligo/amenorrhea. PMID: 30370852 [PubMed - as supplied by publisher] (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - October 29, 2018 Category: Drugs & Pharmacology Authors: Falahat F, Ayatiafin S, Jarahi L, Mokaberinejad R, Rakhshandeh H, Feyzabadi Z, Tavakkoli M Tags: Curr Drug Discov Technol Source Type: research

Vitex negundo and its medicinal value.
Abstract Natural products are rich in several potent bioactive compounds, targeting complex network of proteins involved in various diseases. Vitex negundo (VN), commonly known as "chaste tree", is an ethnobotanically important plant with enormous medicinal properties. Different species of Vitex vary in chemical composition, thus producing different phytochemicals. Several bioactive compounds have been extracted from leaves, seeds, roots in form of volatile oils, flavonoids, lignans, iridoids, terpenes, and steroids. These bioactive compounds exhibit anti-inflammatory, antioxidant, antidiabetic, anticancer...
Source: Molecular Biology Reports - October 11, 2018 Category: Molecular Biology Authors: Gill BS, Mehra R, Navgeet, Kumar S Tags: Mol Biol Rep Source Type: research

Effects of a combination of Nigella sativa and Vitex agnus-castus with citalopram on healthy menopausal women with hot flashes: results from a subpopulation analysis
. (Source: Gynecological Endocrinology)
Source: Gynecological Endocrinology - August 21, 2018 Category: Endocrinology Authors: Maryam Molaie Behrad Darvishi Zahra Jafari Azar Mahboobeh Shirazi Gholamreza Amin Shima Afshar Source Type: research

Integrated in silico-in vitro strategy for screening of some traditional Egyptian plants for human aromatase inhibitors
ConclusionThe suggested strategy provides a reliable means of prospecting in-silico screening of natural products databases in the search for new dug leads as aromatase inhibitors. The hits so obtained can then be subjected to further phytochemical studies, to isolate and identify suitable compounds for further in-vitro testing.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Effects of Vitex agnus-castus extract on the secretory function of pituitary-gonadal axis and pregnancy rate in patients with premature ovarian aging (POA)
ConclusionVAC extract as a fertility-promoting plant appears to be a safe and effective herb for medicinal applications in women with POA when used within the established dosage guidelines. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research

Integrated in silico-in vitro strategy for screening of some traditional Egyptian plants for human aromatase inhibitors
ConclusionThe suggested strategy provides a reliable means of prospecting in-silico screening of natural products databases in the search for new dug leads as aromatase inhibitors. The hits so obtained can then be subjected to further phytochemical studies, to isolate and identify suitable compounds for further in-vitro testing.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - July 6, 2018 Category: Drugs & Pharmacology Source Type: research

Effects of Vitex agnus-castus extract on the secretory function of pituitary-gonadal axis and pregnancy rate in patients with premature ovarian aging (POA)
ConclusionVAC extract as a fertility-promoting plant appears to be a safe and effective herb for medicinal applications in women with POA when used within the established dosage guidelines. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Integrated in silico-in vitro strategy for screening of some traditional Egyptian plants for human aromatase inhibitors
Conclusion The suggested strategy provides a reliable means of prospecting in-silico screening of natural products databases in the search for new dug leads as aromatase inhibitors. The hits so obtained can then be subjected to further phytochemical studies, to isolate and identify suitable compounds for further in-vitro testing. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - June 20, 2018 Category: Drugs & Pharmacology Source Type: research

Herbal Medicine for Oligomenorrhea and Amenorrhea: A Systematic Review of Ancient and Conventional Medicine.
Conclusion. Traditional Persian medicine has proposed many different medicinal plants for treatment of oligomenorrhea and amenorrhea. Although just few plants have been proven to be effective for treatment of menstrual irregularities, the results and the classification in present study can be used as an outline for future studies and treatment. PMID: 29744355 [PubMed - in process] (Source: Biomed Res)
Source: Biomed Res - May 11, 2018 Category: Research Authors: Moini Jazani A, Hamdi K, Tansaz M, Nazemiyeh H, Sadeghi Bazargani H, Fazljou SMB, Nasimi Doost Azgomi R Tags: Biomed Res Int Source Type: research

Effects of Vitex agnus-castus extract on the secretory function of pituitary-gonadal axis and pregnancy rate in patients with premature ovarian aging (POA)
Conclusion VAC extract as a fertility-promoting plant appears to be a safe and effective herb for medicinal applications in women with POA when used within the established dosage guidelines. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - October 28, 2017 Category: Complementary Medicine Source Type: research

IJERPH, Vol. 14, Pages 1209: Toxic Elements in Different Medicinal Plants and the Impact on Human Health
a Local medicinal plants from Madina, Saudi Arabia, are used to cure various diseases. However, some can cause adverse health effects. Five different medicinal plants were collected in the city of Madina: mahareeb (Cymbopogon), sheeh (Artemisia), harjal (Cynanchum argel delile), nabipoot (Equisetum), and kafmariam (Vitex agnus-castus). In total, four toxic elements including Al, Pb, As, and Cd were analyzed using inductively coupled plasma mass spectrometry (ICP-MS). The range of recoveries fell between 86.1 and 90.6% for all measured elements. Al levels were the highest of any of the studied elements in all plant samp...
Source: International Journal of Environmental Research and Public Health - October 11, 2017 Category: Environmental Health Authors: Eid Brima Tags: Article Source Type: research

Assessment of in vitro dopamine-neuroblastoma cell interactions with a bioelectric biosensor: perspective for a novel in vitro functional assay for dopamine agonist/antagonist activity.
Abstract Current receptor-binding assays for dopamine do not measure the in vitro whole cellular response against dopamine or potential agonist/antagonist molecules. We herewith report the development of a novel functional assay concept for studying the in vitro interaction of the neurotransmitter dopamine with neural cells bearing dopamine receptors. The concept is based on the ultra-rapid measurement of changes in the electric properties of cultured N2a mouse neuroblastoma cells (corresponding to cumulative changes of the cell membrane potential). A close relationship between cumulative cell membrane pot...
Source: Talanta - May 15, 2017 Category: Chemistry Authors: Apostolou T, Moschopoulou G, Kolotourou E, Kintzios S Tags: Talanta Source Type: research

The treatment of premenstrual syndrome with  preparations of Vitex agnus castus: a systematic review and meta-analysis
Our objective was to determine the efficacy, tolerability, and acceptability of Vitex agnus castus preparations for treatment of premenstrual syndrome. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - February 22, 2017 Category: OBGYN Authors: Saskia Verkaik, Astrid M. Kamperman, Roos van Westrhenen, Peter F.J. Schulte Tags: Systematic Review Source Type: research

The treatment of premenstrual syndrome with preparations of Vitex agnus castus: A systematic review and meta-analysis
A high risk of bias and the heterogeneity of the included studies preclude a definite conclusion about the effectiveness of treatment of PMS with Vitex agnus castus (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - February 22, 2017 Category: OBGYN Authors: Saskia Verkaik, Astrid M. Kamperman, Roos van Westrhenen, Peter F.J. Schulte Tags: Systematic Review Source Type: research