Essential Oils from Vitex agnus castus L. Leaves Induces Caspase-Dependent Apoptosis of Human Multidrug-Resistant Lung Carcinoma Cells through Intrinsic and Extrinsic Pathways.
This study revealed that VAC EOs may be a promising candidate in the development of novel therapeutic agents for multi-drug resistant lung cancer treatment.
PMID: 32972249 [PubMed - as supplied by publisher] (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - September 24, 2020 Category: Cancer & Oncology Authors: Ilhan S Tags: Nutr Cancer Source Type: research
Essential Oils from Vitex agnus castus L. Leaves Induces Caspase-Dependent Apoptosis of Human Multidrug-Resistant Lung Carcinoma Cells through Intrinsic and Extrinsic Pathways
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - September 24, 2020 Category: Cancer & Oncology Authors: Suleyman Ilhan Source Type: research
Effects of benzene on gilts ovarian cell functions alone and in combination with buckwheat, rooibos, and vitex.
Abstract
We aimed to examine the influence of benzene and of three dimethyl sulfoxide (DMSO) plant extracts-buckwheat (Fagopyrum Esculentum), rooibos (Aspalathus linearis), and vitex, (Vitex Agnus-Castus), and the combination of benzene with these three plant extracts on basic ovarian cell functions. Specifically, the study investigated the influence of benzene (0, 10, 100, or 1000 ng/mL) with and without these three plant additives on porcine ovarian granulosa cells cultured during 2 days with and without these additives. Cell viability, proliferation (accumulation of proliferating cell nuclear antigen, P...
Source: Environmental Science and Pollution Research International - September 10, 2020 Category: Environmental Health Authors: Sirotkin AV, Macejková M, Tarko A, Fabova Z, Alrezaki A, Alwasel S, Harrath AH Tags: Environ Sci Pollut Res Int Source Type: research
Chemical composition and biological activities of the essential oils from Vitex-agnus castus, Ocimum campechianum and Ocimum carnosum.
Abstract
The essential oils obtained by hydrodistillation from fresh leaves of Vitex agnus-castus and Ocimum campechianum, and from fresh inflorescences of Ocimum carnosum were analysed by GC-FID and GC-MS. The major components of V. agnus-castus essential oil were identified as 1,8-cineole (47.9%), terpinyl α-acetate (11.6%), sabinene (11.2%) and caryophyllene oxide (9.7%), while in the O. campechianum essential oil were eugenol (72.1%), β-elemene (6.8%), (E)-caryophyllene (6.4%) and bicyclogermacrene (5.2%). Linalool (79.0%), α-epi-cadinol (5.4%), terpinen-4-ol (3.2%) and 1,8-cineole (2.8%) were the m...
Source: An Acad Bras Cienc - April 23, 2020 Category: Science Authors: Ricarte LP, Bezerra GP, Romero NR, Silva HCD, Lemos TLG, Arriaga AMC, Alves PB, Santos MBD, Militão GCG, Silva TDS, Braz-Filho R, Santiago GMP Tags: An Acad Bras Cienc Source Type: research
Photocatalytic-degradation of organic dye and removal of heavy metal ions using synthesized SnO2 nanoparticles by Vitex agnus-castus fruit via a green route
Publication date: Available online 26 December 2019Source: Materials LettersAuthor(s): J. Ebrahimian, M. Mohsennia, M. KhayatkashaniAbstractThe SnO2 nanoparticles (NPs) have been successfully synthesized by green synthesis method using Vitex agnus-castus fruit extract. The structural properties of prepared NPs were investigated, indicating homogeneous size distribution of spherically shaped NPs with an average particle size of 8 nm. The photocatalytic activity of the SnO2 NPs for degradation of rhodamine B (RhB) dye in aqueous solution under UV irradiation has been investigated. According the results, the dye degradation e...
Source: Materials Letters - December 26, 2019 Category: Materials Science Source Type: research
Facile synthesis of trimetallic nanoparticles Au/CuO/ZnO using Vitex agnus-castus extract and their activity in degradation of organic dyes
. (Source: International Journal of Environmental Analytical Chemistry)
Source: International Journal of Environmental Analytical Chemistry - December 20, 2019 Category: Chemistry Authors: Renata Dobrucka Source Type: research
Vitex agnus-castus in premenstrual syndrome: A meta-analysis of double-blind randomised controlled trials.
Abstract
Although chasteberry (Vitex agnus-castus, VAC) has been studied in several clinical trials and available as medicine for the alleviation of premenstrual syndrome (PMS) symptoms, the efficacy of properly characterised preparations has not been assessed in meta-analyses. The aim of our work was to evaluate the efficacy of VAC in PMS. The meta-analysis was performed following the PRISMA guidelines using the PICOS format, taking into account the CONSORT recommendations. PubMed, Embase, the Cochrane Central Register of Controlled Trials and Web of Science were searched for studies on VAC. The analysis ...
Source: Complementary Therapies in Medicine - November 30, 2019 Category: Complementary Medicine Authors: Csupor D, Lantos T, Hegyi P, Benkő R, Viola R, Gyöngyi Z, Csécsei P, Tóth B, Vasas A, Márta K, Rostás I, Szentesi A, Matuz M Tags: Complement Ther Med Source Type: research
Facile synthesis of trimetallic nanoparticles Au/CuO/ZnO using Vitex agnus-castus extract and their activity in degradation of organic dyes
. (Source: International Journal of Environmental Analytical Chemistry)
Source: International Journal of Environmental Analytical Chemistry - November 13, 2019 Category: Chemistry Authors: Renata Dobrucka Source Type: research
Vitex Agnus-Castus for the Treatment of Cyclic Mastalgia: A Systematic Review and Meta-Analysis
Journal of Women's Health, Ahead of Print. (Source: Journal of Women)
Source: Journal of Women - August 28, 2019 Category: OBGYN Authors: Soo Liang Ooi Stephanie Watts Rhett McClean Sok Cheon Pak Source Type: research
The effects of Vitex agnus-castus on menstrual bleeding: A systematic review and meta-analysis
Authors: Mollazadeh, Sanaz / Mirghafourvand, Mojgan / Abdollahi, Nafiseh Ghassab (Source: Journal of Complementary and Integrative Medicine)
Source: Journal of Complementary and Integrative Medicine - July 30, 2019 Category: Complementary Medicine Source Type: research
Drug-induced psychotic disorder after administration of Vitex agnus castus (chasteberry) medication to treat premenstrual syndrome: a case report
Discussion The standardization of the diagnostic criteria for MCI, as well as the tests used in the cognitive evaluation, could allow the comparison between the studies and would be an important step in the researches of this area. (Source: Revista de Psiquiatria Clinica)
Source: Revista de Psiquiatria Clinica - July 30, 2019 Category: Psychiatry Source Type: research
Quality Assessment of Medicinal Product and Dietary Supplements Containing Vitex agnus-castus by HPLC Fingerprint and Quantitative Analyses.
In this study, we aimed to evaluate the quality of 11 products sold in Japan (one medicinal product and 10 dietary supplements) containing/claiming to contain chasteberry extract (fruit of Vitex agnus-castus L.) using HPLC fingerprint (15 characteristic peaks), quantitative determination of chemical marker compounds, and a disintegration test. The HPLC profile of the medicinal product was similar to that of the reference standard of V. agnus-castus fruit dry extract obtained from European Directive for the Quality of Medicines (EDQM), whereas the profiles of some dietary supplements showed great variability, such as differ...
Source: Chemical and Pharmaceutical Bulletin - June 4, 2019 Category: Drugs & Pharmacology Authors: Sogame M, Naraki Y, Sasaki T, Seki M, Yokota K, Masada S, Hakamatsuka T Tags: Chem Pharm Bull (Tokyo) Source Type: research
Designing an Au/reduced graphene oxide modified carbon paste electrode for the electrochemical quantification of agnuside
This study reported a good linearity in the range of 0.050-250.0 nM and a low detection limit of 0.016 nM. The relative standard deviations (RSDs) for 10.0 nM and 100.0 nM of agnuside were obtained 3.3% and 1.2%, respectively. The sensor was successfully applied to determine agnuside in Vitex agnus castus fruit and urine sample.Graphical abstract (Source: Sensors and Actuators B: Chemical)
Source: Sensors and Actuators B: Chemical - April 2, 2019 Category: Chemistry Source Type: research
The LC/ESI-MSMS Profiles and Biological Potentials of Vitex agnus castus Extracts.
Authors: Ağalar HG, Çiftçi GA, Yιldιrιm SU, Göger F, Kιrιmer N
Abstract
The chemical profile, cytotoxic and apoptotic effect, and antioxidant activity were determined of ethanolic extracts of Vitex agnus-castus L. (chaste tree). Ripened fruits and fruitless aerial parts were extracted with ethanol, and the chemical characterization of the extracts was determined by LC/ESI-MS-MS. Twelve compounds were tentatively identified in the extracts. The dose-dependent cytotoxic effects of the extracts were tested on C6, A549 and MCF-7 cells by using MT7 assay; inhibition of DNA synthesis, and apoptotic and ...
Source: Natural Product Communications - January 2, 2019 Category: Biochemistry Tags: Nat Prod Commun Source Type: research
Optimizing a recombinant estrogen receptor binding assay for analysis of herbal extracts
Publication date: Available online 10 December 2018Source: Journal of Herbal MedicineAuthor(s): Sandra L. Gray, Brett R. LackeyAbstractPhytoestrogens may directly or indirectly affect the function of estrogen receptors. A method using human recombinant estrogen receptors alpha and beta (ERα and ERβ) was adapted for pure isoflavone compounds: glycitein, glycitin, biochanin A and formononetin; and extracts from chaste tree, Queen-Anne’s lace, Cyperus rhizome, dong quai, flaxseed, black cohosh, Siberian ginseng, saw palmetto, hops, licorice, red clover and alfalfa. Estrogen binding equivalents (EBE) for extracts binding w...
Source: Journal of Herbal Medicine - December 11, 2018 Category: Complementary Medicine Source Type: research
