Quiet standing and anteroposterior limits of stability in adolescents and young adults with bilateral spastic cerebral palsy
This study aimed to determine the relationships between the positions and postural sway in the QS and anteroposterior LoS in individuals with BSCP. It included 27 adolescents and young adults with BSCP (BSCP group) and 27 adolescents and young adults without disability (control group). The position of center of pressure in the anteroposterior direction (CoPy position) and the path length of center of pressure (CoP path length) during the QS and the anterior and posterior LoS (A-LoS and P-LoS, respectively) were measured using a force platform. The CoPy positions in the A-LoS and P-LoS in the BSCP group were limited compare...
Source: Human Movement Science - March 29, 2024 Category: Neurology Authors: Hidehito Tomita Daisuke Kawaguchi Shuhei Takahashi Hitoshi Asai Source Type: research
Management and treatment of musculoskeletal problems in adults with cerebral palsy: Experience gained from two lifespan clinics
J Pediatr Rehabil Med. 2024;17(1):19-33. doi: 10.3233/PRM-240018.NO ABSTRACTPMID:38552124 | PMC:PMC10977450 | DOI:10.3233/PRM-240018 (Source: Journal of Pediatric Rehabilitation Medicine)
Source: Journal of Pediatric Rehabilitation Medicine - March 29, 2024 Category: Rehabilitation Authors: Mark Katsma Haiqing Liu Xiaoyu Pan Kyle J Ryan David P Roye Henry G Chambers Source Type: research
The critical need to accelerate cerebral palsy research with consumer engagement, global networks, and adaptive designs
J Pediatr Rehabil Med. 2024;17(1):9-17. doi: 10.3233/PRM-240014.ABSTRACTThe prevalence of cerebral palsy (CP) varies globally, with higher rates and burden of disease in low- and middle-income countries. CP is a lifelong condition with no cure, presenting diverse challenges such as motor impairment, epilepsy, and mental health disorders. Research progress has been made but more is needed, especially given consumer demands for faster advancements and improvements in the scientific evidence base for interventions. This paper explores three strategies to accelerate CP research: consumer engagement, global clinical trial netwo...
Source: Journal of Pediatric Rehabilitation Medicine - March 29, 2024 Category: Rehabilitation Authors: Sruthi P Thomas Iona Novak Anina Ritterband-Rosenbaum Karin Lind Annabel Webb Paul Gross Maria McNamara CP Global Clinical Trials Network Source Type: research
Quiet standing and anteroposterior limits of stability in adolescents and young adults with bilateral spastic cerebral palsy
This study aimed to determine the relationships between the positions and postural sway in the QS and anteroposterior LoS in individuals with BSCP. It included 27 adolescents and young adults with BSCP (BSCP group) and 27 adolescents and young adults without disability (control group). The position of center of pressure in the anteroposterior direction (CoPy position) and the path length of center of pressure (CoP path length) during the QS and the anterior and posterior LoS (A-LoS and P-LoS, respectively) were measured using a force platform. The CoPy positions in the A-LoS and P-LoS in the BSCP group were limited compare...
Source: Human Movement Science - March 29, 2024 Category: Neurology Authors: Hidehito Tomita Daisuke Kawaguchi Shuhei Takahashi Hitoshi Asai Source Type: research
Management and treatment of musculoskeletal problems in adults with cerebral palsy: Experience gained from two lifespan clinics
J Pediatr Rehabil Med. 2024;17(1):19-33. doi: 10.3233/PRM-240018.NO ABSTRACTPMID:38552124 | PMC:PMC10977450 | DOI:10.3233/PRM-240018 (Source: Journal of Pediatric Rehabilitation Medicine)
Source: Journal of Pediatric Rehabilitation Medicine - March 29, 2024 Category: Rehabilitation Authors: Mark Katsma Haiqing Liu Xiaoyu Pan Kyle J Ryan David P Roye Henry G Chambers Source Type: research
The critical need to accelerate cerebral palsy research with consumer engagement, global networks, and adaptive designs
J Pediatr Rehabil Med. 2024;17(1):9-17. doi: 10.3233/PRM-240014.ABSTRACTThe prevalence of cerebral palsy (CP) varies globally, with higher rates and burden of disease in low- and middle-income countries. CP is a lifelong condition with no cure, presenting diverse challenges such as motor impairment, epilepsy, and mental health disorders. Research progress has been made but more is needed, especially given consumer demands for faster advancements and improvements in the scientific evidence base for interventions. This paper explores three strategies to accelerate CP research: consumer engagement, global clinical trial netwo...
Source: Journal of Pediatric Rehabilitation Medicine - March 29, 2024 Category: Rehabilitation Authors: Sruthi P Thomas Iona Novak Anina Ritterband-Rosenbaum Karin Lind Annabel Webb Paul Gross Maria McNamara CP Global Clinical Trials Network Source Type: research
Quiet standing and anteroposterior limits of stability in adolescents and young adults with bilateral spastic cerebral palsy
This study aimed to determine the relationships between the positions and postural sway in the QS and anteroposterior LoS in individuals with BSCP. It included 27 adolescents and young adults with BSCP (BSCP group) and 27 adolescents and young adults without disability (control group). The position of center of pressure in the anteroposterior direction (CoPy position) and the path length of center of pressure (CoP path length) during the QS and the anterior and posterior LoS (A-LoS and P-LoS, respectively) were measured using a force platform. The CoPy positions in the A-LoS and P-LoS in the BSCP group were limited compare...
Source: Human Movement Science - March 29, 2024 Category: Neurology Authors: Hidehito Tomita Daisuke Kawaguchi Shuhei Takahashi Hitoshi Asai Source Type: research
Genes, Vol. 15, Pages 436: An Ultra-Rare Mixed Phenotype with Combined AP-4 and ERF Mutations: The First Report in a Pediatric Patient and a Literature Review
Romano
Bonuccelli
The adaptor protein 4 (AP-4) constitutes a conserved hetero-tetrameric complex within the family of adaptor protein (AP) complex, crucial for the signal-mediated trafficking of integral membrane proteins. Mutations affecting all subunits of the AP-4 complex have been linked to autosomal-recessive cerebral palsy and a complex hereditary spastic paraparesis (HSP) phenotype. Our report details the case of a 14-year-old boy born to consanguineous parents, presenting psychomotor delay, severe intellectual disability, microcephaly, and trigonocephaly. Despite a history of febrile seizures, subsequent...
Source: Genes - March 29, 2024 Category: Genetics & Stem Cells Authors: Orsini Santangelo Carmignani Camporeale Massart Tyutyusheva Peroni Foiadelli Ferretti Toschi Romano Bonuccelli Tags: Article Source Type: research
Comparison of the Efficiency of Transcutaneous Electrical Nerve Stimulation and Manual Therapy in Children with Cerebral Palsy with Lower Urinary System Dysfunction- A Randomized Prospective Trial
Neurological defects in children with cerebral palsy (CP) not only affect their motor skills but also lead to bladder and bowel problems. Although most children with CP have achieved urinary control, more than 50% of cases experience lower urinary tract symptoms (LUTS). Common LUTS complaints observed in CP include delayed toilet training, urinary incontinence, increased frequency of urination, urgency, urinary hesitancy, and recurrent urinary tract infections. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - March 29, 2024 Category: Urology & Nephrology Authors: Betul Unal, Pelin Pisirici, Aygul Koseoglu Kurt, Halil Tugtepe Source Type: research
Identification of Neural and Non-Neural Origins of Joint Hyper-Resistance Based on a Novel Neuromechanical Model
Joint hyper-resistance is a common symptom in neurological disorders. It has both neural and non-neural origins, but it has been challenging to distinguish different origins based on clinical tests alone. Combining instrumented tests with parameter identification based on a neuromechanical model may allow us to dissociate the different origins of joint hyper-resistance in individual patients. However, this requires that the model captures the underlying mechanisms. Here, we propose a neuromechanical model that, in contrast to previously proposed models, accounts for muscle short-range stiffness (SRS) and its interaction wi...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - March 25, 2024 Category: Neuroscience Source Type: research
Prevalence of vitamin D deficiency in children with cerebral palsy: a meta-analysis
The objective of meta-analysis was to estimate the prevalence of vitamin D deficiency in children with CP. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 25, 2024 Category: Neurology Authors: Kamel Awadh Alenazi, Ahmad Ayadah Alanezi Tags: Research Paper Source Type: research
Exploring the sexual experiences and challenges of individuals with cerebral palsy
J Pediatr Rehabil Med. 2024 Mar 22. doi: 10.3233/PRM-240006. Online ahead of print.ABSTRACTPURPOSE: Cerebral palsy (CP) is a prevalent motor disorder affecting children, with evolving demographics indicating an increasing survival into adulthood. This shift necessitates a broader perspective on CP care, particularly in addressing the often overlooked aspect of sexuality. The purpose of this study was to investigate experiences of, challenges with, and related factors of sexuality and intimacy that people with CP are facing.METHODS: This was a descriptive and cross-sectional single institution survey among individuals with ...
Source: Journal of Pediatric Rehabilitation Medicine - March 22, 2024 Category: Rehabilitation Authors: Amber Newell Neal Liang Jan Moskowitz Nancy Lee Xiaoyu Norman Pan Heakyung Kim Source Type: research
Botulinum neurotoxin type A responders among children with spastic cerebral palsy: Pattern-specific effects
CONCLUSION: This comprehensive analysis highlighted the importance of investigating BoNT effects on gait and clinical impairments according to baseline gait patterns. These findings may help identify good treatment responders.PMID:38518417 | DOI:10.1016/j.ejpn.2024.02.017 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - March 22, 2024 Category: Neurology Authors: E Papageorgiou N Peeters L Staut G Molenaers E Ortibus A Van Campenhout K Desloovere Source Type: research
Exploring the sexual experiences and challenges of individuals with cerebral palsy
J Pediatr Rehabil Med. 2024 Mar 22. doi: 10.3233/PRM-240006. Online ahead of print.ABSTRACTPURPOSE: Cerebral palsy (CP) is a prevalent motor disorder affecting children, with evolving demographics indicating an increasing survival into adulthood. This shift necessitates a broader perspective on CP care, particularly in addressing the often overlooked aspect of sexuality. The purpose of this study was to investigate experiences of, challenges with, and related factors of sexuality and intimacy that people with CP are facing.METHODS: This was a descriptive and cross-sectional single institution survey among individuals with ...
Source: Journal of Pediatric Rehabilitation Medicine - March 22, 2024 Category: Rehabilitation Authors: Amber Newell Neal Liang Jan Moskowitz Nancy Lee Xiaoyu Norman Pan Heakyung Kim Source Type: research
Botulinum neurotoxin type A responders among children with spastic cerebral palsy: Pattern-specific effects
CONCLUSION: This comprehensive analysis highlighted the importance of investigating BoNT effects on gait and clinical impairments according to baseline gait patterns. These findings may help identify good treatment responders.PMID:38518417 | DOI:10.1016/j.ejpn.2024.02.017 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - March 22, 2024 Category: Neurology Authors: E Papageorgiou N Peeters L Staut G Molenaers E Ortibus A Van Campenhout K Desloovere Source Type: research
