Repost from Saturday Oct 14: The Queen gets it right with a better image
This is a case I posted Saturday, October 14.This ECG was texted to me after the fact with no information. What do you think?This is the ECG that I used for the post. It is high quality screenshot of a pdf:I had said that the Queen said this is Not OMI with low confidenceHowever, the image that had been texted to me and submitted to the Queen was not this one above. It was this one below: (photo of computer screen, lower quality):This is the image for which the Queen interpreted " Not OMI with Low Confidence "After posting, I wanted to getexplainability for the ECG, and I was unable to get the explainability fr...
Source: Dr. Smith's ECG Blog - October 17, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs
This ECG was handed over at triage. See how the Queen of Hearts AI does with these explainability images.
Submitted by anonymous, written by Pendell MeyersI was at triage when this ECG was presented to me.What do you think?Here ' s what the Queen of Hearts thinks:Note that the Queen has " HIGH " confidence that this is OMI. As noticed by the AI,if the patient presented with chest pain, then even this subtle ECG is diagnostic of OMI. Specifically, this ECG is diagnostic of acuteLAD OMI, with hyperacute T waves likely in V3 and V4, very small but abnormal STE in V2-V4 (because of its there is a lot of STErelative to the very small QRS), and there is also some terminal T wave inversion in V4 which may suggest some elem...
Source: Dr. Smith's ECG Blog - October 15, 2023 Category: Cardiology Authors: Pendell Source Type: blogs
What clinical scenario fits best?
Below are 4 ECGs from the same patient. Accompanying the ECGs is some clinical information. Look at the ECGs and consider the timeline and other information. At the bottom will be five alternative clinical scenarios to explain the findings.Which one do you think fits better with the ECGs and their timeline? The patient is a 60 something female. She was admitted to the hospital with clinical signs of infection. She was febrile and hypotensive at presentation. As part of her work up in the ED an ECG was recorded.What do you think?ECG#1 - day 1The above ECG shows sinus rhythm with a narrow QRS and normal axis. There is B...
Source: Dr. Smith's ECG Blog - October 12, 2023 Category: Cardiology Authors: Magnus Nossen Source Type: blogs
Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
DNA Damage and Consequent Inflammation in Heart Failure
One of the ways in which cell damage characteristic of aging can provoke inflammation is via the mislocalization of DNA. Either nuclear DNA or mitochondrial DNA can find its way to the cytosol, where it can trigger responses evolved to detect bacterial or viral infection, or severe cell damage. This creates a cascade of downstream signaling leading to an inflammatory response. In youth these events occur comparatively rarely, and in circumstances wherein immune response and potentially even cell death are beneficial. With age, however, there is a continued mild but growing level of dysfunction and consequent sustained infl...
Source: Fight Aging! - September 8, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Reviewing Nicotinamide Riboside as a Strategy to Increase NAD Levels
The vitamin B3 derivative nicotinamide riboside is one of the more studied ways to increase nicotinamide adenine dinucleotide (NAD) levels in aged tissues. NAD is important in mitochondrial function, but for incompletely understood reasons becomes less available with advancing age. Delivering precursors to NAD synthesis such as nicotinamide riboside can help to boost NAD levels, but researchers have failed to show that the increase in NAD levels and resulting health benefits of this sort of approach are any better than those produced by regular exercise. Clinical trials of various means of increasing NAD levels have produc...
Source: Fight Aging! - September 8, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Q & A With Dylan Burnette: Muscle Cells, Cell Movement, and Microscopy
Courtesy of Dr. Dylan Burnette.
“We scientists know very little of what can be known—I find that invigorating,” says Dylan Burnette, Ph.D., an associate professor of cell and developmental biology at Vanderbilt University School of Medicine in Nashville, Tennessee. “Most people find it exhausting, but I’m comfortable with not knowing all of biology’s secrets.” In an interview, Dr. Burnette shared his lab’s work on muscle cells, the knowledge he hopes readers take away from his research, and some advice to future scientists about being comfortable being wrong.
Q: How did you first become interested in s...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 6, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cellular Imaging Cellular Processes Profiles Source Type: blogs
Dip and plateau pattern of ventricular pressure tracing in constrictive pericarditis
Thickened and stiff pericardium in chronic constrictive pericarditis has poor compliance reducing the distension of cardiac chambers to a limited fixed total volume. Transmission of intrathoracic pressure to the pericardial cavity is also prevented by thickening of the pericardium [1]. Manifestation of compression occurs when the total cardiac volume reaches the pericardial volume in diastole. The severe restriction causes elevation of pulmonary and systemic venous pressure which becomes equal to diastolic pressures in all cardiac chambers. Relative change is more on the right sided chambers. Inspiratory fall in intratho...
Source: Cardiophile MD - August 31, 2023 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
New ESC 2023 Cardiomyopathy guidelines: Truths trail by 17 years!
It was 2006
Allow me to recount an unassuming piece of a PowerPoint presentation from my institute, Madras Medical College, at the annual Cardiological Society meeting in New Delhi. The paper was categorized under miscellaneous sessions. I vividly remember the day. I have to admit, It was a nearly empty hall E, located in the basement of Hotel Ashoka. After the talk, I looked up to find that neither the chairman nor the handful of kind academic souls had any questions or comments to make. Pausing for a few moments, I quietly walked down the podium with an inexplicable silent pain.
The title of the presentation was &#...
Source: Dr.S.Venkatesan MD - August 27, 2023 Category: Cardiology Authors: dr s venkatesan Tags: cardiomyopathy Dilated cardiomyopathy hypertrophic cardiomyopathy ischemic cardiomyopathy Uncategorized drsvenkatesan ESC 2023 new cardiomyopathy guideline ndlvc non dilated cardiomyopathy Source Type: blogs
Bonus Features – August 20, 2023 – Healthcare orgs only use 57% of their data to drive decision-making, digital health is well represented on the Inc. 5000 list, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News
The annual Inc. 5000 list is live. Digital health companies on the list include AngelEye Health, Authenticx, DAS Health, FarmboxRX, ixlayer, Mytonomy, Reveleer, TigerConnect, TimelyCare, Valenz Health, Veda, and Vytalize He...
Source: EMR and HIPAA - August 20, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT 1upHealth 4medica Accelecom AliveCor Anahi Santiago AngelEye Health Authenticx AVIA Azalea Health Boston Children's Hospital C3HIE Center for Virtual Care Value and Equity Cerner Cerner CommunityWorks Christiana Source Type: blogs
Zilebesiran: A Promising Leap Forward In Hypertension Management
Conclusion
As we draw the curtain on this insightful dive into Zilebesiran, a couple of takeaways stand out. Zilebesiran, the promising twice-yearly shot, is opening new frontiers in hypertension management.
With its ability to suppress angiotensin production, it offers a fresh approach that could alleviate the burden of daily pill regimens. But the shot is still in its developmental phase, and further research is crucial to fully understand its capabilities and limitations.
Still, it’s important to remember that medications are only a part of the solution. The enduring message from health professionals is ...
Source: The EMT Spot - July 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
This was texted to me in real time. The patient has acute chest pain.
This was texted to me in real time. The patient has acute chest pain.What do you think?Here was my answer:" Not ischemia. Chronic. Maybe HOCM or another form of LVH. I would not activate cath lab. Get serial troponins "It is a scary ECG, with a lot of ST Elevation and what appear to be hyperacute T-waves in inferior leads, and profound reciprocal ST Depression in aVL. There are Q-waves in V4-V6, with what appear to be hyperacute T-waves. Any objective, rule-based analysis of this ECG would scream " STEMI " or " OMI " . But, alas, ECGs are like faces. No measurements can t...
Source: Dr. Smith's ECG Blog - July 5, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs
Poor Long Term Outcome With Subsequent Pregnancies After Peripartum Cardiomyopathy
This study was from a single centre where mortality in women with peripartum cardiomyopathy was higher than in other studies from the United Studies. Most of the patients were African American and of low socioeconomic status. Earlier studies have clearly demonstrated a different phenotypic presentation and outcome in African American women with peripartum cardiomyopathy compared to non-African American women. African American women had been shown to be diagnosed later, present lower LVEF, larger LV volume and more severe heart failure symptoms. The rate of recovery was lower and time for recovery markedly longer in that pa...
Source: Cardiophile MD - June 28, 2023 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Young Man with Very Fast Regular Wide Complex Tachycardia
EMS was dispatched for a 30-something male who feels his heart is racing. Sudden onset.The patient had no previous medical history.Vitals were normal except for a heart rate of 226.A prehospital 12-lead was recorded:There is a regular wide complex tachycardia. The computer diagnosed this as Ventricular Tachycardia.Is it definitely VT??The patient was given 6mg, then 12 mg, of adenosine, without a change in the rhythm.He arrived in the ED and had an immediate bedside cardiac ultrasound while this ECG was being recorded.The bedside ultrasound (video not available) reportedly showed only a slightly reduced LV func...
Source: Dr. Smith's ECG Blog - June 28, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs
Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models.
The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
