Zoom Fatigue and Other Symptoms of Pandemic Teaching | TAPP 73
What causesZoom fatigue and how can we prevent it? Host Kevin Patton tackles that as well as another nasty effect of pandemic teaching:stress cardiomyopathy. Plus updates insensory physiology, the value of keepingskill lists, and theBook Club recommends Chris Jarmey'sConcise Book of Muscles.00:40 | Updating Our Skill Lists01:59 | Updates in Sensory Physiology07:30 | Sponsored by AAA08:05 | Book Club: The Concise Book of Muscles12:05 | Sponsored by HAPI14:26 | Zoom Fatigue29:11 | Sponsored by HAPS30:06 | Pandemic Heart: Stress Cardiomyopathy39:48 | Staying ConnectedIf you cannot see or activate...
Source: The A and P Professor - July 14, 2020 Category: Physiology Authors: Kevin Patton Source Type: blogs

Fight Aging! Newsletter, July 6th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - July 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Autophagy in Cardiovascular Aging is a Complicated Matter
Cell and tissue biology always turns out to be more complicated than we would all prefer. Present understanding is rarely complete to the point at which all obstacles are known. It is one of the reasons why the development of new classes of medical therapy is a challenging business. Consider the topic of autophagy in aging, for example. Autophagy is the name given to a collection of processes responsible for recycling unwanted and damaged molecules and structures in the cell. Material is conveyed, in one way or another depending on the type of autophagy, to a lysosome and engulfed. Lysosomes are membrane-bound packages of ...
Source: Fight Aging! - July 2, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Repost: 63 minutes of ventricular fibrillation, followed by shock. What is going on?
In this study, 5% of VF arrest was due to PE: V fib is initial rhythm in PE in 3 of 60 cases. On the other hand, if the presenting rhythm is PEA, then pulmonary embolism is likely.  When there is VF in PE, it is not the initial rhythm, but occurs after prolonged PEA renders the myocardium ischemic.--Another study by Courtney and Kline found that, of cases of arrest that had autopsy and found that a presenting rhythm of VF/VT had an odds ratio of 0.02 for massive pulmonary embolism as the etiology, vs 41.9 for PEA.    ===================================MY Comment by KEN ...
Source: Dr. Smith's ECG Blog - June 27, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs

Diffuse T-wave inversions and a very long QT
This ECG was texted to me and I read it while mountain biking. My response was " takotsubo " .ECG 1There is are diffuse T-wave inversions and a bizarre QT interval, very longThis is very typical of takotsubo.Aside: I classify takotsubo ECGs into 2 broad categories:1) ST Elevation which often mimics STEMI2) T-wave inversion: does not mimic STEMI, but rather mimics NonSTEMI or reperfused STEMIThe next day I texted back to ask what the clinical presentation was, what the echo showed, and what the outcome was.It turned out that this patient had severe alcoholism, alcohol withdrawal, and seemed to have had an alcohol ...
Source: Dr. Smith's ECG Blog - June 21, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs

Syncope and ST Elevation on the Prehospital ECG
DiscussionThus, no further ECGs were recorded and there was no angiogram or stress test or CT coronary angiogram.  Acute MI does not often present with syncope alone, without any other symptom, so the pretest probability of acute MI is low.However, the troponins are high and, in my opinion, the data above does not rule out the possibility of type 1 MI.  There were very elevated troponins without a significant known stress (which might cause a type 2 MI).  The troponins are NOT consistent with STEMI (OMI), which typically has a troponin I of at least 5 ng/mL.  Nevertheless, I don ' t think a thrombosis r...
Source: Dr. Smith's ECG Blog - June 19, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs

Link between LV dysfunction & VPDs … Is it a cause or bcoz ?
We know, LV dysfunction of any etiology can cause VPDs.This must be differentiated from VPDs induced LV dysfunction. Mind you, this is not an easy job at all. When do you suspect excess VPDs are the cause (or might cause) of LV dysfunction?In young, otherwise healthy persons with “VPDs and LV dysfunction”  would suggest chronic abnormal electrical activity is the cause for subsequent LV dysfunction. (An expression of electromechanical remodeling) Monomorphic VPDs more often suggest primary electrical pathology(Like OTVT, Fascicular VT)VPD count more than >10000 in 24 hrs in Holter will probably I...
Source: Dr.S.Venkatesan MD - May 28, 2020 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized av desynchrony due to vpd influence of vpd on crt PVC induced cardiomyopathy tachycardic cardiomyopathy what is the relation between LV dysfunction and VPD vpc pvc Source Type: blogs

Adverse effects of hydroxychloroquine
In case you were ever stupid enough to follow Trump’s lead you would have already injected ultraviolets in your eyeballs by now to save you from Covid and maybe bathed in Domestos or sulfuric acid or both! Anyway, his latest bullshine claim is that he’s been taking the antimalarial drug hydroxychloroquine to keep Covid at bay. Well, for starters there is no evidence that this drug acts as a prophylactic against infection with SARS CoV-2 or indeed any pathogen other than the causative agent of otherwise drug-resistant malaria. It’s primary use is in treating lupus. There was some testing done weeks ago to...
Source: David Bradley Sciencebase - Songs, Snaps, Science - May 19, 2020 Category: Science Authors: David Bradley Tags: Health and Medicine Source Type: blogs

Difficult calls in cardiology : Be ready for DC cardioversion during pregnancy !
This report from Taiwan  reassures there is no adverse effect by measuring umbilical artery flow (Yu-Chi Wang European Journal of Obstetrics & Gynecology and Reproductive Biology 126 (2006) 268–274)While we consider DC shock during pregnancy is safe for the fetus, still, shock pads close to the abdomen, amniotic fluid being a good conductor of electricity at least one mother showed a sustained contraction of the uterus and fetal distress. This was possibly attributable to DC shock  Eleanor J. Barnes BJOG 2003 https://doi.org/10.1046/j.1471-0528.2002.02113. Final message Most cardiac arrhythmias in pregnancy ...
Source: Dr.S.Venkatesan MD - May 11, 2020 Category: Cardiology Authors: dr s venkatesan Tags: cardiology women Pregnancy and heart Uncategorized amiodarone verapamil in pregnancy avnrt avrt during pregnancy cardioversion during pregnancy dc shock during pregnancy fetal distress during dc shock peripartum cardiomyopathy vt vpd managem Source Type: blogs

A man in his 50s with fever and shortness of breath
Written by Pendell MeyersA man in his 50s with HTN, HLD, obesity, and restrictive lung disease presented with shortness of breath worsening over the past 3 days. He also had a cough and subjective fevers. He denied chest pain. His vitals were within normal limits.Here is his triage ECG (no baseline available):What do you think?Findings: - sinus rhythm at about 100 bpm - STE in I and aVL (meets STEMI criteria) - hint of STD in III and aVF - STD in V1 and V2 - hyperacute T-waves in I and aVL (with reciprocal negative hyperacute T in III)Interpretation:This is definitive evidence of acute transmural i...
Source: Dr. Smith's ECG Blog - May 10, 2020 Category: Cardiology Authors: Pendell Source Type: blogs

Hypertension induced by tyrosine kinase inhibitor
Well known adverse effect of chemotherapeutic agents are cardiomyopathy and myocarditis leading to heart failure and arrhythmias. Hypertension induced by tyrosine kinase inhibitor (TKI) is an important adverse effect and has specific mechanisms. Hypertension is noted with vascular endothelial growth factor (VEGF) and vascular signalling pathway (VSP) inhibitors [1]. The incidence ranges from 5% to 80% among VEGF inhibitors and is dose dependent. Incidence of hypertension is lower in new generation small molecule TKI [1]. Mechanism of hypertension is through vascular signally pathway inhibition which causes decrease in nit...
Source: Cardiophile MD - April 27, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardio Oncology Source Type: blogs

Mortality in hypertrophic cardiomyopathy – Cardiology MCQ – Answer
Mortality in hypertrophic cardiomyopathy – Cardiology MCQ – Answer Disease specific mortality in hypertrophic cardiomyopathy –  Correct answer: a) 0.5% per year Hypertrophic cardiomyopathy (HCM) is the commonest among heritable heart diseases, with prevalence of about one in 500 individuals [1]. HCM is often highlighted as the leading cause of sudden death in young adults and athletes [2]. Still the absolute annual mortality in HCM is not high with availability of current treatment modalities including the implantation of cardioverter-defibrillator to prevent sudden death. It has been reported t...
Source: Cardiophile MD - April 19, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

Mortality in hypertrophic cardiomyopathy – Cardiology MCQ
Mortality in hypertrophic cardiomyopathy – Cardiology MCQ Disease specific mortality in hypertrophic cardiomyopathy: a) 0.5% per year b) 5% per year c) 10 % per year d) 15% per year Click here for the correct answer and discussion The post Mortality in hypertrophic cardiomyopathy – Cardiology MCQ appeared first on All About Cardiovascular System and Disorders. (Source: Cardiophile MD)
Source: Cardiophile MD - April 18, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

A man in his 30s with chest pain
Written by Pendell Meyers, case submitted by Tom FieroA man in his 30s walked into the ED complaining of chest pain. His triage ECG was done at 11:30 (no prior was available):What do you think?Sinus tachycardiaNormal QRS complex pattern, with borderline low voltageVery slight STE in leads V2-V5Proportionally large and fat T-waves in V4-5 with straightening of the ST segmentsT-waves also concerning in II, III, aVF, with inappropriately negative T-waves in aVLUsing the LAD OMI vs. BER formula:3 Variable: 27.34 (positive for OMI, using STE60V3=1.5mm, QTc=444, RWV4=2.0mm)4 Variable: 23.01 (positive for OMI, using QRS amplitude...
Source: Dr. Smith's ECG Blog - March 28, 2020 Category: Cardiology Authors: Pendell Source Type: blogs

A patient with abdominal pain associated with alcohol withdrawal and alcoholic ketoacidosis
While at work, one my partners showed me this ECG of a 50-something woman with abdominal pain associated with alcohol withdrawal and alcoholic ketoacidosis.  There was no reported chest pain or SOB.What do you think?I said it " looks like takotsubo.  Electrolytes might contribute.  Are they back yet? (they were not).  I do not think this is a coronary event. "He asked why.I responded: " bizarre T-waves, with T-wave inversion and extremely long QT.  The computer measures the QT at 506 ms, but it really is more like 560-580 ms, with a QTc of 600-620 ms.  This is not at all typical of ACS but ver...
Source: Dr. Smith's ECG Blog - March 24, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs