Cardiac Resynchronization Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Determination of sensed and paced atrial ‐ventricular delay in cardiac resynchronization therapy
ConclusionsA novel methodology for measuring electrical dyssynchrony was used to determine electrically optimal SAVD/PAVD during LV-only pacing. When BiV pacing, shorter AVDs produce better electrical synchrony. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - March 14, 2024 Category: Cardiology Authors: Alan J. Bank, Christopher D. Brown, Kevin V. Burns, Katie M. Johnson Tags: ELECTROPHYSIOLOGY Source Type: research

Conduction System Pacing as Cardiac Resynchronization Therapy in patients with Heart Failure with Reduced Ejection Fraction: More Optimism than Caution!
Cardiac resynchronization therapy (CRT) with biventricular (BiV) pacing is indicated as first line therapy for patients with severely reduced left ventricular ejection fraction (LVEF), heart failure symptoms and wide QRS, but particularly left bundle branch block (LBBB) who are on guideline-directed medical therapy. There is now an abundance of data showing improved quality of life, improvement in LVEF, decreased HF hospitalization and mortality in this patient population. Guidelines recommend BiV pacing as the gold standard for achieving CRT for patients with heart failure with severely reduced EF (HFrEF) LVEF ≤35% and ...
Source: Heart Rhythm - March 14, 2024 Category: Cardiology Authors: Pranav Mankad, Kenneth A. Ellenbogen Source Type: research

Immediate pharmacotherapy intensification after cardiac resynchronization therapy: incidence, characteristics, and impact
ConclusionsImmediate intensification of HF medication was achieved in 54% of CRT recipients and was significantly higher in patients without excessive QRS prolongation, preserved renal function, and dilated cardiomyopathy than others. In patients with LBBB morphology and QRS ≥ 120 ms, IPI was associated with a significantly better prognosis and fewer HF hospitalizations after CRT implantation than others. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 12, 2024 Category: Cardiology Authors: Kojiro Ogawa, Hiro Yamasaki, Kazutaka Aonuma, Masafumi Otani, Ai Hattori, Masako Baba, Kentaro Yoshida, Miyako Igarashi, Hidetaka Nishina, Kou Suzuki, Akihiko Nogami, Masaki Ieda Tags: Original Article Source Type: research

Dropping the floor on QRS duration boundaries for CRT patient selection in 2024- effects of sex, race, height and heart size
Cardiac resynchronization therapy (CRT) improves clinical outcomes in selected heart failure (HF) patients. Does it reach all possible candidates - or are some missed? (Source: Heart Rhythm)
Source: Heart Rhythm - March 11, 2024 Category: Cardiology Authors: Niraj Varma Source Type: research

Dropping the floor on QRS duration boundaries for CRT patient selection in 2024 —effects of sex, race, height, and heart size
Cardiac resynchronization therapy (CRT) improves clinical outcomes in selected heart failure (HF) patients. Does it reach all possible candidates —or are some missed? (Source: Heart Rhythm)
Source: Heart Rhythm - March 11, 2024 Category: Cardiology Authors: Niraj Varma Tags: Editorial Commentary Source Type: research

Preimplant myopenia and clinical outcomes among patients with heart failure undergoing cardiac resynchronization therapy
(Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - March 9, 2024 Category: Cardiology Source Type: research

Comparisons of Long-Term Clinical Outcomes with Left Bundle Branch Pacing, Left Ventricular Septal Pacing and Biventricular Pacing for Cardiac Resynchronization Therapy
Left bundle branch pacing (LBBP) and left ventricular septal pacing (LVSP) are referred to as left bundle branch area pacing (LBBAP). (Source: Heart Rhythm)
Source: Heart Rhythm - March 8, 2024 Category: Cardiology Authors: Haojie Zhu, Chaotong Qin, Anjie Du, Qian Wang, Chen He, Fengwei Zou, Xiaofei Li, Jin Tao, Chuangshi Wang, Zhimin Liu, Siyuan Xue, Jiaxin Zeng, Zhiyong Qian, Yao Wang, Xiaofeng Hou, Kenneth A. Ellenbogen, Michael R. Gold, Yan Yao, Jiangang Zou, Xiaohan Fan Source Type: research

Cardiomyopathy with an LMNA Genetic Variant Affecting Three Consecutive Generations: A Case Series
We report the case of a family afflicted with cardiac laminopathy who showed atrial fibrillation (AF) and complete atrioventricular block across three generations. Implantable cardioverter defibrillators (ICDs) implantation, or cardiac resynchronization therapy (CRT) were delivered to the three patients (proband; 61 years old, proband's mother: 84 years old, and proband's daughter; 38 years old) to prevent sudden cardiac death or suppress heart failure progression. A novel frameshift mutation (LMNA Exon 9: c.1550dupA;p. N518Efs*34) was found in all three cases through genetic testing, and this mutation may potentially resu...
Source: Internal Medicine - March 3, 2024 Category: Internal Medicine Authors: Naoko Ogawa Hidekazu Kondo Yumi Ishii Kazuki Mitarai Kumiko Akiyoshi Hiroko Niwa Koichi Kato Minoru Horie Seiko Ohno Naohiko Takahashi Source Type: research

Complications of left bundle branch area pacing compared with biventricular pacing in candidates for resynchronization therapy: Results of a propensity score-matched analysis from a multicenter registry
Cardiac resynchronization therapy (CRT) with biventricular pacing (BVP) is a well-established therapy in patients with reduced left ventricular ejection fraction (LVEF), heart failure, and left bundle branch (LBB) block. LBB area pacing (LBBAP) has recently been shown to be a feasible and effective alternative to BVP. Comparative data on the risk of complications between LBBAP and BVP among patients undergoing CRT are lacking. (Source: Heart Rhythm)
Source: Heart Rhythm - February 28, 2024 Category: Cardiology Authors: Pietro Palmisano, Gabriele Dell ’Era, Federico Guerra, Ernesto Ammendola, Matteo Ziacchi, Mattia Laffi, Paolo Donateo, Alessandro Guido, Chiara Ghiglieno, Antonio Parlavecchio, Antonio Dello Russo, Gerardo Nigro, Mauro Biffi, Germano Gaggioli, Jacopo Se Source Type: research

Multipoint pacing for cardiac resynchronization: Is the MPP juice worth the battery squeeze?
In this issue of the Journal, Passafaro and colleagues present the results of a clinical study evaluating the use of non-invasive hemodynamics to guide the choice of standard vs. multipoint pacing (MPP) for cardiac resynchronization therapy (CRT)(1). Before discussing the results, it would be useful to provide some context for the impetus to perform this study. Despite a wealth of evidence over the past two decades to support the use of CRT in patients with heart failure reduced ejection fraction and wide QRS, the rate of non-response to CRT (variably defined) has remained stubbornly at ∼25-35%(2). (Source: The American ...
Source: The American Journal of Cardiology - February 24, 2024 Category: Cardiology Authors: Wissam Mekary, Faisal M. Merchant Tags: Editorial Source Type: research