Long-term prognosis and prognostic factors after primary prophylactic implantable cardioverter-defibrillator therapy
CONCLUSIONS: Prior NSVT before ICD implantation was not an independent predictor of future MACE in patients with HFrEF with primary prophylactic ICD. In contrast, atrial fibrillation was associated with worse prognosis. To predict the prognosis of patients with primary prophylactic ICD, these factors should be assessed as comprehensive risk stratification factors for MACE.PMID:38382578 | DOI:10.1016/j.jjcc.2024.02.006 (Source: Journal of Cardiology)
Source: Journal of Cardiology - February 21, 2024 Category: Cardiology Authors: Masafumi Sugawara Yusuke Kondo Satoko Ryuzaki Yutaka Yoshino Toshinori Chiba Ryo Ito Takatsugu Kajiyama Masahiro Nakano Yoshio Kobayashi Source Type: research

Long-term prognosis and prognostic factors after primary prophylactic implantable cardioverter-defibrillator therapy
CONCLUSIONS: Prior NSVT before ICD implantation was not an independent predictor of future MACE in patients with HFrEF with primary prophylactic ICD. In contrast, atrial fibrillation was associated with worse prognosis. To predict the prognosis of patients with primary prophylactic ICD, these factors should be assessed as comprehensive risk stratification factors for MACE.PMID:38382578 | DOI:10.1016/j.jjcc.2024.02.006 (Source: Journal of Cardiology)
Source: Journal of Cardiology - February 21, 2024 Category: Cardiology Authors: Masafumi Sugawara Yusuke Kondo Satoko Ryuzaki Yutaka Yoshino Toshinori Chiba Ryo Ito Takatsugu Kajiyama Masahiro Nakano Yoshio Kobayashi Source Type: research

Long-term prognosis and prognostic factors after primary prophylactic implantable cardioverter-defibrillator therapy
CONCLUSIONS: Prior NSVT before ICD implantation was not an independent predictor of future MACE in patients with HFrEF with primary prophylactic ICD. In contrast, atrial fibrillation was associated with worse prognosis. To predict the prognosis of patients with primary prophylactic ICD, these factors should be assessed as comprehensive risk stratification factors for MACE.PMID:38382578 | DOI:10.1016/j.jjcc.2024.02.006 (Source: Journal of Cardiology)
Source: Journal of Cardiology - February 21, 2024 Category: Cardiology Authors: Masafumi Sugawara Yusuke Kondo Satoko Ryuzaki Yutaka Yoshino Toshinori Chiba Ryo Ito Takatsugu Kajiyama Masahiro Nakano Yoshio Kobayashi Source Type: research

Role of speckle tracking echocardiography beyond current guidelines in cardiac resynchronization therapy
Cardiac resynchronization therapy (CRT) is a device-based treatment applied to patients with a specific profile of heart failure. According to current guidelines, indication for CRT is given on the basis of QRS morphology and duration, and traditional transthoracic echocardiography is mainly used to estimate left ventricular (LV) ejection fraction. However, the identification of patients who may benefit from CRT remains challenging, since the application of the above-mentioned guidelines is still associated with a high rate of non-responders. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - February 19, 2024 Category: Cardiology Authors: Simona Sperlongano, Giovanni Benfari, Federica Ilardi, Matteo Lisi, Alessandro Malagoli, Giulia Elena Mandoli, Maria Concetta Pastore, Donato Mele, Matteo Cameli, Antonello D'Andrea, Echocardiography Working Group of the Italian Society of Cardiology Source Type: research

Personalized Cardiac Resynchronization Therapy Guided by Real-time Electrocardiographic Imaging for Non-Left Bundle Branch Block patients
Heart failure patients with non-left bundle branch block (non-LBBB) QRS pattern have limited response rate to biventricular pacing (BVP). (Source: Heart Rhythm)
Source: Heart Rhythm - February 16, 2024 Category: Cardiology Authors: Tsz-Kin Tam, Alex C.K. Au, Joseph Y.S. Chan, Chin-Pang Chan, Li-Li Cheung, Yuet-Wong Cheng, Fiona S.M. Yuen, Bryan P. Yan Source Type: research

A step forward towards conduction system pacing –based cardiac resynchronization therapy, albeit a small one.
Starting from the very first clinical reports of the deep septal pacing technique by Mafi-Rad et al. and Huang et al., it became clear that the activation of the left ventricle (LV) during pacing near the left conduction system (the method known as left bundle branch area pacing – LBBAP) results in paced QRS that, in contrast to the conventional right ventricular pacing technique, has none of the features of left bundle branch block.1;2 On the contrary, the reported LBBAP paced QRS complexes showed rapid activation over the LV and demonstrates right bundle branch block pa ttern. (Source: Heart Rhythm)
Source: Heart Rhythm - February 15, 2024 Category: Cardiology Authors: Marek Jastrz ębski, Pugazhendhi Vijayaraman Source Type: research

Efficacy of Left Bundle Branch Area Pacing Versus Biventricular Pacing in Cardiac Resynchronization Therapy Patients: Select Site - Cohort Study
Cardiac resynchronization therapy (CRT) is typically attempted with biventricular pacing. One-third of patients are non-responders. Left bundle branch area pacing (LBBAP) has been evaluated as an alternative means. (Source: Heart Rhythm)
Source: Heart Rhythm - February 15, 2024 Category: Cardiology Authors: Jenish P. Shroff, Deep Chandh Raja, Lukah Q. Tuan, Sreevilasam P. Abhilash, Abhinav Mehta, Walter P. Abhayaratna, Prashanthan Sanders, Rajeev K. Pathak Source Type: research

A step forward toward conduction system pacing –based cardiac resynchronization therapy, albeit a small one
Starting from the very first clinical reports of the deep septal pacing technique by Mafi-Rad and coworkers1 and Huang and coworkers,2 it became clear that the activation of the left ventricle (LV) during pacing near the left conduction system —the method known as left bundle branch area pacing (LBBAP)—results in paced QRS that in contrast to the conventional right ventricular pacing technique has none of the features of left bundle branch block (LBBB). On the contrary, the reported LBBAP paced QRS complexes showed rapid activation ov er the LV and demonstrated right bundle branch block pattern. (Source: Heart Rhythm)
Source: Heart Rhythm - February 15, 2024 Category: Cardiology Authors: Marek Jastrz ębski, Pugazhendhi Vijayaraman Tags: Editorial Commentary Source Type: research

Efficacy of left bundle branch area pacing versus biventricular pacing in patients treated with cardiac resynchronization therapy: Select site – cohort study
Cardiac resynchronization therapy (CRT) is typically attempted with biventricular (BiV) pacing. One-third of patients are nonresponders. Left bundle branch area pacing (LBBAP) has been evaluated as an alternative means. (Source: Heart Rhythm)
Source: Heart Rhythm - February 15, 2024 Category: Cardiology Authors: Jenish P. Shroff, Deep Chandh Raja, Lukah Q. Tuan, Sreevilasam P. Abhilash, Abhinav Mehta, Walter P. Abhayaratna, Prashanthan Sanders, Rajeev K. Pathak Source Type: research

Clinical Utility of QRS Duration Normalized to Left Ventricular Volume for Predicting Cardiac Resynchronization Therapy Efficacy in Patients with "Mid-Range" QRS Duration
Cardiac resynchronization therapy (CRT) is effective for patients with heart failure with a QRS duration (QRSd)> 150 milliseconds (ms). However, its beneficial effect appears to be limited for those with a "mid-range" QRSd (120 –149 ms). Recent studies have demonstrated that modifying the QRSd to left ventricular end-diastolic volume (LVEDV), modified QRSd, improves the prediction of clinical outcomes of CRT. (Source: Heart Rhythm)
Source: Heart Rhythm - February 14, 2024 Category: Cardiology Authors: Nobuhiko Yamamoto, Takashi Noda, Makoto Nakano, Tomohiro Ito, Hiroyuki Sato, Hideka Hayashi, Takahiko Chiba, Yuhi Hasebe, Nobuhiko Ueda, Tsukasa Kamakura, Kohei Ishibashi, Satoshi Miyata, Kengo Kusano, Satoshi Yasuda Source Type: research

Relationship between Sex, Body Size, and Cardiac Resynchronization Therapy Benefit: A Patient Level Meta-Analysis of Randomized Controlled Trials
Women might benefit more from cardiac resynchronization therapy(CRT) than men, and do so at shorter QRS durations(QRSd). (Source: Heart Rhythm)
Source: Heart Rhythm - February 13, 2024 Category: Cardiology Authors: Daniel J. Friedman, Antonio Olivas-Martinez, Frederik Dalgaard, Marat Fudim, William T. Abraham, John G.F. Cleland, Anne B. Curtis, Michael R. Gold, Valentina Kutyifa, Cecilia Linde, Anthony S. Tang, Fatima Ali-Ahmed, Lurdes Y.T. Inoue, Gillian D. Sanders Source Type: research

Relationship between sex, body size, and cardiac resynchronization therapy benefit: A patient-level meta-analysis of randomized controlled trials
Women might benefit more than men from cardiac resynchronization therapy (CRT) and do so at shorter QRS durations. (Source: Heart Rhythm)
Source: Heart Rhythm - February 13, 2024 Category: Cardiology Authors: Daniel J. Friedman, Antonio Olivas-Martinez, Frederik Dalgaard, Marat Fudim, William T. Abraham, John G.F. Cleland, Anne B. Curtis, Michael R. Gold, Valentina Kutyifa, Cecilia Linde, Anthony S. Tang, Fatima Ali-Ahmed, Lurdes Y.T. Inoue, Gillian D. Sanders Source Type: research

Challenges and pitfalls during CRT implantation in patients with persistent left superior vena cava
ConclusionsThis case series shows that although challenging, conventional endovascular CRT implantation is feasible in PLSVC patients. Specialized tools for visualization and fixation may help. Our experiences highlight the importance of preprocedural evaluation of the anatomy and precise intervention planning.Graphical Abstract (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - February 12, 2024 Category: Cardiology Source Type: research