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Fasciculo-Ventricular Pathways As A Mechanism Of Bundle Branch Block Correction: An Intriguing But Not Unfalsifiable Hypothesis
His bundle pacing (HBP) can correct the ECG appearance of left bundle branch block (LBBB) at least as effectively as biventricular pacing for cardiac resynchronization therapy (CRT).1 Although more distal left-sided conduction system pacing, left bundle branch pacing (LBBP), has risen to prominence in recent years, HBP-CRT ’s remarkable ability to apparently normalize conduction system function in both ventricles has entrenched it as an important modality, with guideline endorsement.2 Importantly, this meteoric rise has occurred despite some uncertainty regarding the mechanism by which HBP is able to normalize the E CG a...
Source: Heart Rhythm - January 31, 2024 Category: Cardiology Authors: Ahran D. Arnold, Pugazhendhi Vijayaraman Source Type: research

Fasciculoventricular pathways as a mechanism of bundle branch block correction: An intriguing but not unfalsifiable hypothesis
His bundle pacing (HBP) can correct the electrocardiographic (ECG) appearance of left bundle branch block (LBBB) at least as effectively as biventricular pacing for cardiac resynchronization therapy (CRT).1 Although more distal left-sided conduction system pacing —left bundle branch pacing—has risen to prominence in recent years, HBP-CRT’s remarkable ability to apparently normalize conduction system function in both ventricles has entrenched it as an important modality, with guideline endorsement. (Source: Heart Rhythm)
Source: Heart Rhythm - January 31, 2024 Category: Cardiology Authors: Ahran D. Arnold, Pugazhendhi Vijayaraman Tags: Editorial Commentary Source Type: research

Perioperative Management of Patients with Cardiac Implantable Electronic Devices
Korean J Anesthesiol. 2024 Jan 29. doi: 10.4097/kja.23826. Online ahead of print.ABSTRACTThe use of cardiac implantable electronic devices (CIEDs) has increased significantly in recent years. Consequently, more patients with CIEDs will undergo surgery during their lifetime, and thus the involvement of anesthesiologists in the perioperative management of CIEDs is increasing. With ongoing advancements in technology, many types of CIEDs have been developed, including permanent pacemakers, leadless pacemakers, implantable cardioverter defibrillators, cardiac resynchronization therapy-pacemakers/defibrillators, and implantable ...
Source: Korean Journal of Anesthesiology - January 29, 2024 Category: Anesthesiology Authors: Minsu Kim Chang Hee Kwon Source Type: research

Treatment strategy for heart failure complicated with complete left bundle branch block and atrial tachycardia: a case report
ConclusionFor patients with heart failure combined with left bundle branch block and atrial tachycardia, left bundle branch area pacing can replace traditional biventricular pacing for cardiac resynchronization therapy treatment, and the therapeutic effect is significant. However, multiple factors need to be considered when formulating strategies, including whether there is bundle branch block under sinus rhythm, the success and recurrence rate of atrial tachycardia ablation, the response of cardiac resynchronization therapy, the costs of different strategies, and instrument implantation issues. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 27, 2024 Category: General Medicine Source Type: research

Cardiac resynchronization therapy for pacing induced cardiomyopathy: Role of baseline right ventricular pacing burden
ConclusionA higher baseline RV pacing burden predicts a greater improvement in LVEF after CRT upgrade for PICM. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - January 26, 2024 Category: Cardiology Authors: Ahmed Shahab, Sean Lacy, Jonathan K. Chandler, Seth H. Sheldon, Rhea C. Pimentel, Raghuveer A. Dendi, Rigoberto R. Ramirez, Martin P. Emert, Loren D. Berenbom, Y. Madhu Reddy, Nachiket Apte, Amit Noheria Tags: ORIGINAL ARTICLE Source Type: research

Integration of implantable device therapy in patients with heart failure. A clinical consensus statement from the Heart Failure Association (HFA) and European Heart Rhythm Association (EHRA) of the European Society of Cardiology (ESC)
Implantable devices form an integral part of the management of patients with heart failure (HF) and provide adjunctive therapies in addition to cornerstone drug treatment. Although the number of these devices is growing, only few are supported by robust evidence. Current devices aim to improve haemodynamics, improve reverse remodelling, or provide electrical therapy. A number of these devices have guideline recommendations and some have been shown to improve outcomes such as cardiac resynchronization therapy, implantable cardioverter-defibrillators and long-term mechanical support. For others, more evidence is still needed...
Source: European Journal of Heart Failure - January 25, 2024 Category: Cardiology Authors: Wilfried Mullens, Jeroen Dauw, Finn Gustafsson, Alexandre Mebazaa, Jan Steffel, Klaus K. Witte, Victoria Delgado, Cecilia Linde, Kevin Vernooy, Stefan D. Anker, Ovidiu Chioncel, Davor Milicic, Gerd Hasenfu ß, Piotr Ponikowski, Ralph Stephan Tags: Position Paper Source Type: research

Clinical characteristics and outcome of cardiac resynchronization therapy for heart failure in National Hospital of Sri Lanka from year 2005 to 2020 – a retrospective observational study
Cardiac resynchronization therapy (CRT) has been a well-established treatment modality for moderate to severe left ventricular systolic dysfunction with left ventricular desynchrony. This is the pioneering stu... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - January 23, 2024 Category: Cardiology Authors: Sandun Prabath Iddagoda Hewage Don, Kuruppumullage Chamini Nuwansika Kuruppu, Asunga Dunuwille, Asanka Wijewardena and Rohan Gunawardena Tags: Research Source Type: research

De novo versus upgrade cardiac resynchronization therapy: A different patient population and outcome?
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 18, 2024 Category: Cardiology Authors: B éla Merkely, Annamária Kosztin Tags: Invited Editorial Source Type: research

COMPArison of Multi-Point Pacing and ConvenTional CRT Through Non-invasive Hemodynamics Measurement: Short and Long Term Results of the COMPACT-MPP Study
Invasive hemodynamic studies have demonstrated improved left ventricular (LV) performances when cardiac resynchronization therapy/defibrillator (CRT-D) is delivered through multi-point pacing (MPP). Nowadays, strategies that allow to study the same hemodynamic parameters at a non-invasive level have become available. The aim of the present study was to evaluate the clinical implication of using a patient-tailored approach for CRT programming based on non-invasively assessed LV hemodynamics to identify the best biventricular pacing modality between standard single-site pacing (STD) and MPP for each patient. (Source: The Ame...
Source: The American Journal of Cardiology - January 16, 2024 Category: Cardiology Authors: Francesco Passafaro, Antonio Rapacciuolo, Antonio Ruocco, Giuseppe Ammirati, Salvatore Crispo, Eugenia Pasceri, Giuseppe Santarpia, Ciro Mauro, Giovanni Esposito, Ciro Indolfi, Antonio Curcio Source Type: research

COMPArison of Multi-Point Pacing and ConvenTional Cardiac Resynchronization Therapy Through Noninvasive Hemodynamics Measurement: Short- and Long-Term Results of the COMPACT-MPP Study
Invasive hemodynamic studies have shown improved left ventricular (LV) performances when cardiac resynchronization therapy/defibrillator is delivered through multipoint pacing (MPP). Nowadays, strategies have become available that allow studying the same hemodynamic parameters at a noninvasive level. The aim of the present study was to evaluate the clinical implication of using a patient-tailored approach for cardiac resynchronization therapy programming based on noninvasively assessed LV hemodynamics to identify the best biventricular pacing modality between standard single-site pacing (STD) and MPP for each patient. (Sou...
Source: The American Journal of Cardiology - January 16, 2024 Category: Cardiology Authors: Francesco Passafaro, Antonio Rapacciuolo, Antonio Ruocco, Giuseppe Ammirati, Salvatore Crispo, Eugenia Pasceri, Giuseppe Santarpia, Ciro Mauro, Giovanni Esposito, Ciro Indolfi, Antonio Curcio Source Type: research

Add-on Sacubitril/Valsartan Therapy Induces Left Ventricular Remodeling in Non-responders to Cardiac Resynchronization Therapy to a Similar Extent as in Heart Failure Patients Without Resynchronization
ConclusionSV therapy induced similar improvements in echocardiographic parameters and in NT-proBNP levels in CRT-NR patients and in patients with HFrEF without resynchronization. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - January 12, 2024 Category: Cardiology Source Type: research

Caudal fluoroscopic guidance for the insertion of transvenous pacing leads
ConclusionCaudal fluoroscopy for axillary/subclavian access is associated with a lower rate of pneumothorax and contrast venography compared with an AP approach. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - January 11, 2024 Category: Cardiology Authors: Matthew B. Morton, Jeremy William, Peter M. Kistler, Sandeep Prabhu, Hariharan Sugumar, Olivier Van Den Brink, Hitesh Patel, Justin Mariani, Aleksandr Voskoboinik Tags: ORIGINAL ARTICLE Source Type: research

Interaction between cardiac resynchronization therapy and cytokines in heart failure patients
In this study, we have reviewed the immunological processes involved in heart failure and the effect of CRT in controlling of the cytokine storm.PMID:38199086 | DOI:10.1016/j.cyto.2023.156479 (Source: Cytokine)
Source: Cytokine - January 10, 2024 Category: Molecular Biology Authors: Seyyed Shamsadin Athari Entezar Mehrabi Nasab Kai Jing Jin Wang Source Type: research

Motion correction of wide-detector 4DCT images for cardiac resynchronization therapy planning
Lead placement at the latest mechanically activated left ventricle (LV) segments is strongly correlated with response to cardiac resynchronization therapy (CRT). We demonstrate the feasibility of a cardiac 4DCT motion correction algorithm (ResyncCT) in estimating LV mechanical activation for guiding lead placement in CRT. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 10, 2024 Category: Radiology Authors: Ashish Manohar, James Yang, Jed D. Pack, Gordon Ho, Elliot R. McVeigh Tags: Research paper Source Type: research

Single/Dual Chamber vs. Cardiac Resynchronization Pacemakers for Cardiac Resynchronization – Results from the SYNCHRONY Collaborative Group
In patients with heart failure (HF) undergoing left bundle branch area pacing (LBBAP) for cardiac resynchronization therapy (CRT) without a defibrillator (e.g., elderly patients or non-ischemic cardiomyopathy, in whom the use of a defibrillator has been questioned),1 the use of a right ventricular (RV) lead may not be necessary. However, in some countries CRT is not reimbursed if a 3-lead device is not used, and the clinical impact of avoiding this additional lead has not been established. (Source: Heart Rhythm)
Source: Heart Rhythm - January 3, 2024 Category: Cardiology Authors: Juan C. Diaz, Mauricio Duque, Andres F. Miranda, Bruce A. Koplan, Jorge E. Mar ín, Julian M. Aristizabal, Cesar D. Niño, Oriana Bastidas, Daniela Hincapie, Carolina Hoyos, Carlos D. Matos, Nestor Lopez-Cabanillas, Elmer Jaraba, Sebastian Moreno, Manuel Source Type: research