Multipoint pacing for cardiac resynchronization: Is the MPP juice worth the battery squeeze?

In this issue of the Journal, Passafaro and colleagues present the results of a clinical study evaluating the use of non-invasive hemodynamics to guide the choice of standard vs. multipoint pacing (MPP) for cardiac resynchronization therapy (CRT)(1). Before discussing the results, it would be useful to provide some context for the impetus to perform this study. Despite a wealth of evidence over the past two decades to support the use of CRT in patients with heart failure reduced ejection fraction and wide QRS, the rate of non-response to CRT (variably defined) has remained stubbornly at ∼25-35%(2).
Source: The American Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research