Complications of left bundle branch area pacing compared with biventricular pacing in candidates for resynchronization therapy: Results of a propensity score-matched analysis from a multicenter registry
Cardiac resynchronization therapy (CRT) with biventricular pacing (BVP) is a well-established therapy in patients with reduced left ventricular ejection fraction (LVEF), heart failure, and left bundle branch (LBB) block. LBB area pacing (LBBAP) has recently been shown to be a feasible and effective alternative to BVP. Comparative data on the risk of complications between LBBAP and BVP among patients undergoing CRT are lacking. (Source: Heart Rhythm)
Source: Heart Rhythm - February 28, 2024 Category: Cardiology Authors: Pietro Palmisano, Gabriele Dell ’Era, Federico Guerra, Ernesto Ammendola, Matteo Ziacchi, Mattia Laffi, Paolo Donateo, Alessandro Guido, Chiara Ghiglieno, Antonio Parlavecchio, Antonio Dello Russo, Gerardo Nigro, Mauro Biffi, Germano Gaggioli, Jacopo Se Source Type: research

Multipoint pacing for cardiac resynchronization: Is the MPP juice worth the battery squeeze?
In this issue of the Journal, Passafaro and colleagues present the results of a clinical study evaluating the use of non-invasive hemodynamics to guide the choice of standard vs. multipoint pacing (MPP) for cardiac resynchronization therapy (CRT)(1). Before discussing the results, it would be useful to provide some context for the impetus to perform this study. Despite a wealth of evidence over the past two decades to support the use of CRT in patients with heart failure reduced ejection fraction and wide QRS, the rate of non-response to CRT (variably defined) has remained stubbornly at ∼25-35%(2). (Source: The American ...
Source: The American Journal of Cardiology - February 24, 2024 Category: Cardiology Authors: Wissam Mekary, Faisal M. Merchant Tags: Editorial Source Type: research

Cardiac contractility modulation in patients with heart failure — A review of the literature
AbstractExperimental in vivo and in vitro studies showed that electric currents applied during the absolute refractory period can modulate cardiac contractility. In preclinical studies, cardiac contractility modulation (CCM) was found to improve calcium handling, reverse the foetal myocyte gene programming associated with heart failure (HF), and facilitate reverse remodeling. Randomized control trials and observational studies have provided evidence about the safety and efficacy of CCM in patients with HF. Clinically, CCM therapy is indicated to improve the 6-min hall walk, quality of life, and functional status of HF pati...
Source: Heart Failure Reviews - February 23, 2024 Category: Cardiology Source Type: research

Heart Rhythm New Zealand consensus statement on the practical management of cardiac implanted electronic devices in the peri-operative environment
N Z Med J. 2024 Feb 23;137(1590):77-92. doi: 10.26635/6965.6363.ABSTRACTElectrosurgery is commonly used during a range of operations in order to maintain effective haemostasis. This can cause electromagnetic interference (EMI) with cardiac implanted electronic devices (CIEDs), which prevents normal device function. CIEDs include pacemakers (PPM), implantable cardiac defibrillators (ICD), cardiac resynchronisation therapy devices-both pacemakers and defibrillators (CRT-P/CRT-D)-and implantable loop recorders (ILRs). Damage to the generator, inhibition of pacing, activation of asynchronous pacing and ventricular fibrillation...
Source: New Zealand Medical Journal - February 22, 2024 Category: General Medicine Authors: Emma Guglietta Sharron Denekamp Susan Sinclair Lucy Harris Paula Bishop Nivashni Naidoo Timothy Holliday Mathew Chacko Ross Downey Janice Swanapillai Andrew Martin Matthew Webber Source Type: research