A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining
This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC...
Source: Braz J Med Biol Res - November 16, 2023 Category: Research Authors: S M Fernezlian C M Baldavira M L F de Souza C Farhat A F de Vilhena J C N Pereira J R M de Campos T Takagaki M L Balancin A M Ab'Saber V L Capelozzi Source Type: research
A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining
This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC...
Source: Brazilian Journal of Medical and Biological Research - November 16, 2023 Category: Research Authors: S M Fernezlian C M Baldavira M L F de Souza C Farhat A F de Vilhena J C N Pereira J R M de Campos T Takagaki M L Balancin A M Ab'Saber V L Capelozzi Source Type: research
A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining
This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC...
Source: Braz J Med Biol Res - November 16, 2023 Category: Research Authors: S M Fernezlian C M Baldavira M L F de Souza C Farhat A F de Vilhena J C N Pereira J R M de Campos T Takagaki M L Balancin A M Ab'Saber V L Capelozzi Source Type: research
A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining
This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC...
Source: Brazilian Journal of Medical and Biological Research - November 16, 2023 Category: Research Authors: S M Fernezlian C M Baldavira M L F de Souza C Farhat A F de Vilhena J C N Pereira J R M de Campos T Takagaki M L Balancin A M Ab'Saber V L Capelozzi Source Type: research
A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining
This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC...
Source: Braz J Med Biol Res - November 16, 2023 Category: Research Authors: S M Fernezlian C M Baldavira M L F de Souza C Farhat A F de Vilhena J C N Pereira J R M de Campos T Takagaki M L Balancin A M Ab'Saber V L Capelozzi Source Type: research
A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining
This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC...
Source: Brazilian Journal of Medical and Biological Research - November 16, 2023 Category: Research Authors: S M Fernezlian C M Baldavira M L F de Souza C Farhat A F de Vilhena J C N Pereira J R M de Campos T Takagaki M L Balancin A M Ab'Saber V L Capelozzi Source Type: research
A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining
This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC...
Source: Braz J Med Biol Res - November 16, 2023 Category: Research Authors: S M Fernezlian C M Baldavira M L F de Souza C Farhat A F de Vilhena J C N Pereira J R M de Campos T Takagaki M L Balancin A M Ab'Saber V L Capelozzi Source Type: research
A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining
This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC...
Source: Brazilian Journal of Medical and Biological Research - November 16, 2023 Category: Research Authors: S M Fernezlian C M Baldavira M L F de Souza C Farhat A F de Vilhena J C N Pereira J R M de Campos T Takagaki M L Balancin A M Ab'Saber V L Capelozzi Source Type: research
A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining
This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC...
Source: Braz J Med Biol Res - November 16, 2023 Category: Research Authors: S M Fernezlian C M Baldavira M L F de Souza C Farhat A F de Vilhena J C N Pereira J R M de Campos T Takagaki M L Balancin A M Ab'Saber V L Capelozzi Source Type: research
A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining
This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC...
Source: Brazilian Journal of Medical and Biological Research - November 16, 2023 Category: Research Authors: S M Fernezlian C M Baldavira M L F de Souza C Farhat A F de Vilhena J C N Pereira J R M de Campos T Takagaki M L Balancin A M Ab'Saber V L Capelozzi Source Type: research
Cancers, Vol. 15, Pages 5440: Lung Carcinoids: A Comprehensive Review for Clinicians
edayati
Lung carcinoids are neuroendocrine tumors, categorized as typical or atypical carcinoids based on their histological appearance. While most of these tumors are slow-growing neoplasms, they still possess malignant potential. Many patients are diagnosed incidentally on chest X-rays or CT scans. Presenting symptoms include cough, hemoptysis, wheezing, dyspnea, and recurrent pneumonia. Endocrine symptoms, such as carcinoid syndrome or ectopic Cushing’s syndrome, are rare. Surgery is the primary treatment and should be considered in all patients with localized disease, even when thoracic lymph node met...
Source: Cancers - November 16, 2023 Category: Cancer & Oncology Authors: Dan Granberg Carl Christofer Juhlin Henrik Falhammar Elham Hedayati Tags: Review Source Type: research
A Challenging Case of Ectopic ACTH Syndrome with Bronchial Carcinoid and Literature Review
J Clin Res Pediatr Endocrinol. 2023 Nov 9. doi: 10.4274/jcrpe.galenos.2023.2023-7-6. Online ahead of print.ABSTRACTHere we report an adolescent boy diagnosed with ectopic ACTH (Adrenocorticotropin hormone) syndrome (EAS) caused by atypical bronchial carcinoid. The patient was evaluated multidisciplinaryly: he had surgery and took chemotherapy and radiotherapy treatments afterward. The patient is still under our follow-up. Until today eighteen pediatric and adolescent patients with EAS because of bronchial carcinoid tumors were reported in 13 case reports and literature reviews. Ectopic ACTH syndrome caused by bronchial car...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - November 9, 2023 Category: Endocrinology Authors: Sema Nilay Abseyi Zeynep Şıklar Elif Özsu Ayten Kay ı Cangır Emel Cabi Ünal Nurdan Ta çyıldız Zehra Aycan Merih Berbero ğlu Source Type: research
Radiological-pathological correlation in diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH): imaging and histopathology
CONCLUSION: CT can be used to predict pathological DIPNECH in the appropriate clinical setting. It is important to consider DIPNECH to avoid overdiagnosis of more sinister conditions such as lung cancer or metastases.PMID:37945436 | DOI:10.1016/j.crad.2023.10.013 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - November 9, 2023 Category: Cancer & Oncology Authors: M Gutierrez A Alonso D Penha M Ntouskou J Gosney M Radike Source Type: research
A Challenging Case of Ectopic ACTH Syndrome with Bronchial Carcinoid and Literature Review
J Clin Res Pediatr Endocrinol. 2023 Nov 9. doi: 10.4274/jcrpe.galenos.2023.2023-7-6. Online ahead of print.ABSTRACTHere we report an adolescent boy diagnosed with ectopic ACTH (Adrenocorticotropin hormone) syndrome (EAS) caused by atypical bronchial carcinoid. The patient was evaluated multidisciplinaryly: he had surgery and took chemotherapy and radiotherapy treatments afterward. The patient is still under our follow-up. Until today eighteen pediatric and adolescent patients with EAS because of bronchial carcinoid tumors were reported in 13 case reports and literature reviews. Ectopic ACTH syndrome caused by bronchial car...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - November 9, 2023 Category: Endocrinology Authors: Sema Nilay Abseyi Zeynep Şıklar Elif Özsu Ayten Kay ı Cangır Emel Cabi Ünal Nurdan Ta çyıldız Zehra Aycan Merih Berbero ğlu Source Type: research
