The Present Popularity of Epigenetic Reprogramming to Treat Aging
A fair number of research groups are presently working on ways to force large numbers of cells in the body to adopt more youthful epigenetic profiles. Much of this research is an outgrowth of the discovery of induced pluripotency, the ability to reprogram any cell into a pluripotent stem cell that is largely indistinguishable from an embryonic stem cell, capable of generating any of the cell types in the body. This process also happens to reset many of the epigenetic markers of age that are found in cells in old tissues, alongside restoring mitochondrial function by clearing out damaged mitochondria, and a few other intere...
Source: Fight Aging! - August 9, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
A Proposal to Improve Healthcare and Make It More Affordable
By STEVE ZECOLA
Americans spend about $3 trillion
per year on healthcare, or about $10,000 per person per year. Despite these
expenditures, Americans are worse off than their international counterparts
with respect to infant mortality, life expectancy and the prevalence of chronic
conditions.
In policy debates, Republicans
mostly prefer to let the marketplace devise the appropriate outcomes, but this
approach ignores the market failures that plague the industry.
On the other hand, Democrats propose
a variety of solutions such as “Medicare for All” which nationalizes all
healthcare insurance or, as a variant, ...
Source: The Health Care Blog - August 6, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy Medicare For All Source Type: blogs
Fight Aging! Newsletter, July 29th 2019
In this study we show, for the first time, significant alterations in cholesterol efflux capacity in adolescents throughout the range of BMI, a relationship between six circulating adipocyte-derived EVs microRNAs targeting ABCA1 and cholesterol efflux capacity, and in vitro alterations of cholesterol efflux in macrophages exposed to visceral adipose tissue adipocyte-derived EVs acquired from human subjects. These results suggest that adipocyte-derived EVs, and their microRNA content, may play a critical role in the early pathological development of ASCVD.
Commentary on the Developing UK Government Position on Hea...
Source: Fight Aging! - July 28, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
HPV vaccine: A vaccine that works, and one all children should get
Human papillomavirus, or HPV, is the most common sexually transmitted infection. Most of the time, the body clears it without problems. But when it doesn’t, it can lead to cancer. HPV is the leading cause of cervical cancer, and it can also lead to cancers of the vagina, vulva, penis, anus, and mouth. Every year, there are more than 40,000 cases of cancer caused by HPV.
The HPV vaccine can prevent most of them.
Research shows the HPV vaccine is effective
A study published in the journal Pediatrics underlined just how effective the vaccine is. Researchers studied women ages 13 to 26 between 2006 and 2017, looking at thei...
Source: Harvard Health Blog - July 26, 2019 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Men's Health Parenting Vaccines Women's Health Source Type: blogs
The Role of mTOR as a Regulator of Lifespan
The mTOR gene is deeply involved in the regulation of cellular activities in response to nutrient sensing. It is also implicated in the many, many changes that occur to slow aging in response to a restricted calorie intake, including processes known to be important to aging such as mitochondrial function and cellular senescence. Given that most research to date on intervention in the aging process has focused on the calorie restriction response and related upregulation of stress response mechanisms, it is no surprise that mTOR has attracted a lot of attention. The first mTOR inhibitor drugs are already going through clinic...
Source: Fight Aging! - July 23, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
