TWiV 1090: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus before discussing uptake of the RSV vaccine Abrysvo or the monoclonal anti-RSV antibody nirsevimab to prevent severe disease following RSV infection in infants 8 months or younger before going over this week’s influenza virus and SARS-CoV-2 virus statistics, including all circulating variants in the US, examines if self-testing is more accurate than clinician administered Binax rapid diagnostic tests for SARS-CoV-2 infection, if N95 masks need a yearly fitting, how SARS-CoV-2 vaccination impacts the prev...
Source: This Week in Virology - MP3 Edition - February 24, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

COVID-19 Vaccination in Pregnancy and in Children, Climate Change and Health Series, Thyroid Cancer Review, and more
Editor’s Summary by Christopher W. Seymour, MD, MSc, Associate Editor of JAMA, the Journal of the American Medical Association, for the February 6, 2024, issue. Related Content: Audio Highlights (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - February 6, 2024 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Cervical cancer could be eliminated: here's how
Cervical cancer is both treatable and preventable, and the WHO has called for countries to come together to to eliminate the disease in the next century.However the disease still kills over 300,000 people each year, and levels of screening, treatment and vaccination need to be stepped up in order to achieve this goal.These challenges are particularly stark in low- and middle-income countries, where a lack of funding, staffing and infrastructure are obstacles. Vaccine hesitancy, especially in light of the COVID-19 pandemic, is also a key problem.In this Podcast Extra, two experts share their thoughts on how best to overcome...
Source: Nature Podcast - February 4, 2024 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 1980: AI builds better viruses
TWiV reviews global measles outbreaks, toilet-generated aerosols that spread viruses, highly effective prevention of invasive cervical cancer by HPV vaccination, and design of improved adenovirus-associated viral vectors using machine learning. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Jay Nel...
Source: This Week in Virology - MP3 Edition - January 28, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1061: Seasonal COVID and a niche for cervical cancer
TWiV reveals a prediction of the expected endemic seasonality of COVID-19, based on circulation of human coronaviruses, and ecological clearance of vaccine-targeted human papillomaviruses and an increase in circulation of non-targeted virus types. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommi...
Source: This Week in Virology - MP3 Edition - November 12, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Even a 'minimal cell' can grow stronger, thanks to evolution
In this episode:00:46 The effects of evolution on a minimal genomeIn 2016, researchers created a ‘minimal cell’ bacterium with a genome that only contains genes essential for the organism's survival. Any mutation in these genes could be fatal, so it was unclear whether there could be scope for evolution. But now, a team has grown this bacterium through 2,000 generations and shown that it does have the ability to evolve and can recover from some of the fitness costs associated with its streamlined genome.Research article: Moger-Reischer et al.09:21 Research HighlightsDolphins use ‘baby talk’ when talking to their of...
Source: Nature Podcast - July 5, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 991: The cancer mRNA shot
On this episode of TWiV, the observation that the 1918 influenza virus is not lethal in nonhuman primates and implications for studies on viral virulence, and mRNA vaccines that control and resolve human papillomavirus-associated cancers in mice. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Register for ASV 2023 •MicrobeTV Discord Server •1918 influenza virus not lethal in nonhuman primates (J Virol) •mRNA vaccines control HPV-associated tumors (Sci Trans Med) •Letters read on TWiV 991 •Timestamps by Jolene. Thanks! Weekly Picks Dickson ...
Source: This Week in Virology - MP3 Edition - March 12, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 942: Omicron boosters with Paul Offit
Paul Offit returns to TWiV for a discussion of SARS-CoV-2 bivalent boosters containing ancestral and Omicron spike mRNAs, including their composition, why they are being recommended by CDC, and who would benefit the most from them. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit,  Kathy Spindler, and Brianne Barker Guest: Paul Offit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) CDC oversells bivalent booster (Wall St Journal) FDA authorizes biva...
Source: This Week in Virology - MP3 Edition - October 2, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Wildfires could threaten ozone layer, and vaccinating against tick bites
Could wildfires be depleting the ozone all over again? Staff Writer Paul Voosen talks with host Sarah Crespi about the evidence from the Polarstern research ship for wildfire smoke lofting itself high into the stratosphere, and how it can affect the ozone layer once it gets there. Next, we talk ticks—the ones that bite, take blood, and can leave you with a nasty infection. Andaleeb Sajid, a staff scientist at the National Cancer Institute, joins Sarah to talk about her Science Translational Medicine paper describing an mRNA vaccine intended to reduce the length of tick bites to before the pests can transmit diseases to ...
Source: Science Magazine Podcast - November 18, 2021 Category: Science Authors: Science Magazine Source Type: podcasts

Wildfires could threaten ozone layer, and vaccinating against tick bites
Could wildfires be depleting the ozone all over again? Staff Writer Paul Voosen talks with host Sarah Crespi about the evidence from the Polarstern research ship for wildfire smoke lofting itself high into the stratosphere, and how it can affect the ozone layer once it gets there. Next, we talk ticks—the ones that bite, take blood, and can leave you with a nasty infection. Andaleeb Sajid, a staff scientist at the National Cancer Institute, joins Sarah to talk about her Science Translational Medicine paper describing an mRNA vaccine intended to reduce the length of tick bites to before the pests can transmit diseases...
Source: Science Magazine Podcast - November 18, 2021 Category: Science Authors: Science Magazine Source Type: podcasts

TWiV 759: Pork dogs and an evolutionary pickle
TWiV examines spillovers of porcine and canine coronaviruses into humans in Haiti and Malaysia, and how antigenic evolution of measles virus is constrained by multiple co-dominant epitopes on the viral glycoproteins. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Amy Rosenfeld Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV vaccine town halls 15:10 Porcine deltacoronavirus in Haitian children (medRxiv) Canine coronavirus from Malaysian pneumonia patient (Clin Inf Dis) No shift, measles (TWiV 340) The Cancer Thief (TWiV Letters rea...
Source: This Week in Virology - MP3 Edition - May 23, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 697: The sky is NOT falling
TWiV reviews the latest data on the UK variant of SARS-CoV-2, including some properties of the variant and why it is being closely studied, development of liver cancer in a participant in a adenovirus-associated virus gene therapy trial, and answers to listener questions. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode BSL-3 Assistant Manager position 3:39 NERVTAG meeting minutes (pdf) NERVTAG Preliminary genomic characterization of UK variant (virological.org) PHE investigation of UK var...
Source: This Week in Virology - MP3 Edition - December 24, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Latest Data On SurVaxM Vaccine: Doubled Progression Free Period, Patients Are Surviving About 30 Months On Vaccine, Standard Of Care Median Survival Of 15 Months
Michael Ciesielski, Phd @mjciesielski Of Roswell Park Cancer Institute Discusses Latest Data On SurVaxM Vaccine: Doubled Progression Free Period, Patients Are Surviving About 30 Months On Vaccine, Sta... Author: Annual-Meeting Added: 06/06/2019 (Source: Oncology Tube)
Source: Oncology Tube - June 6, 2019 Category: Cancer & Oncology Source Type: podcasts

TWiV 528: Our annual recapsidation
In the first episode for 2019, the TWiV team reviews the amazing virology stories of the past year. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Please take the TWiV listener survey ASV 2019 Satellite Symposia Crowdfunding for EV-D68 research TWiV World Tour 2018 t-shirt (Amazon) Cool virology from 2018 Viruses behind AD? TWiV 505, TWiV 519, clinical trial one and two Wolbachia-mosquito release halts dengue (TWiV 506); World Mosquito Program Evolutionary history of RNA...
Source: This Week in Virology - MP3 Edition - January 6, 2019 Category: Virology Authors: Vincent Racaniello Source Type: podcasts