Wildfires could threaten ozone layer, and vaccinating against tick bites

Could wildfires be depleting the ozone all over again? Staff Writer Paul Voosen talks with host Sarah Crespi about the evidence from the Polarstern research ship for wildfire smoke lofting itself high into the stratosphere, and how it can affect the ozone layer once it gets there. Next, we talk ticks—the ones that bite, take blood, and can leave you with a nasty infection. Andaleeb Sajid, a staff scientist at the National Cancer Institute, joins Sarah to talk about her Science Translational Medicine paper describing an mRNA vaccine intended to reduce the length of tick bites to before the pests can transmit diseases to a host. This week’s episode was produced with help from Podigy. [Image: Janice Haney Carr/Centers for Disease Control and Prevention; Music: Jeffrey Cook] [Alt text: digitally colorized scanning electron microscopic image of a grouping of Borrelia burgdorferi bacteria, the causative agent of Lyme disease] Authors: Sarah Crespi; Paul VoosenSee omnystudio.com/listener for privacy information.
Source: Science Magazine Podcast - Category: Science Authors: Source Type: podcasts

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ult D Abstract One quarter of all cancers are linked to infectious diseases. The link between viral infection and cancer has been widely studied, but few reports have focused on the carcinogenic role of bacterial infection. Nonetheless, Helicobacter pylori, Chlamydia psittaci, Coxiella burnetii, Borrelia burgdorferi and Campylobacter jejuni are bacteria that can be associated with non-Hodgkin's lymphoma (NHL), the most common haematologic malignancy. Here, we review the evidence in favour of a link between these bacterial infections and NHL. Sero-epidemiological observation makes it possible to identify a link bet...
Source: Critical Reviews in Microbiology - Category: Microbiology Authors: Tags: Crit Rev Microbiol Source Type: research
In this study, the proteomic profile of the surface-associated proteins from M. bovis BCG Moreau was compared to the BCG Pasteur reference strain. The methodology used was 2DE gel electrophoresis combined with mass spectrometry techniques (MALDI-TOF/TOF), leading to the identification of 115 proteins. Of these, 24 proteins showed differential expression between the two BCG strains. Furthermore, 27 proteins previously described as displaying moonlighting function were identified, 8 of these proteins showed variation in abundance comparing BCG Moreau to Pasteur and 2 of them presented two different domain hits. Moonlighting ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Clinical Significance of Human Papillomavirus Type 16 for Breast Cancer &Adenocarcinomas of Various Internal Organs and Alzheimer's Brain with Increased β-amyloid (1-42); Combined Use of Optimal Doses of Vitamin D3 and Taurine 3 times/day Has Significant Beneficial Effects of Anti-Cancer, Anti-Ischemic Heart, and Memory &Other Brain Problems By Significant Urinary Excretion of Viruses, Bacteria, and Toxic Metals &Substances. Acupunct Electrother Res. 2016;41(2):127-134 Authors: Omura Y Abstract Human Papillomavirus type 16 (HPV-16) has a significant role in various cancers and Alzheime...
Source: Acupuncture and Electro-Therapeutics Research - Category: Complementary Medicine Tags: Acupunct Electrother Res Source Type: research
Abstract Experimental Lyme arthritis provides a mouse model for exploring the development of pathology following infection of C3H mice with Borrelia burgdorferi. Infected mice develop a reliable inflammatory arthritis of the ankle joint with severity that typically peaks around two to three weeks post-infection and then undergoes spontaneous resolution. This makes experimental Lyme arthritis an excellent model for investigating the mechanisms that drive both the development and resolution phases of inflammatory disease. Eicosanoids are powerful lipid mediators of inflammation and are known to regulate multiple asp...
Source: Biochimie - Category: Biochemistry Authors: Tags: Biochimie Source Type: research
The following Q&A is a continuation of an interview with Tara Moriarty, proprietor of the Moriarty Lab, an infectious diseases research lab that studies primarily Borrelia burgdorferi (Bb) the bacterium that causes Lyme disease. Moriarty is the principal investigator of a new academic paper from the University of Toronto that details the mechanism by which Bb "crawl" through the body -- a scholarly article that turned out to be unexpectedly popular. Tara Moriarty (Photo by Jeff Comber) How do you think your findings about the biomechanics of Lyme disease bacteria may affect treatment of the...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
This study evaluated antibiotic vs placebo. The study was terminated early due to the determined likelihood that a beneficial effect would not be found. When this was critically analyzed with biostatistical methods, an article was published which I believe demonstrates that Klempner's study was so poorly designed and analyzed that in order for a treatment effect to have been observed, the antibiotic treated patients would have had to improve to a level of health which was a full standard deviation better than the average health of the general population. It's a reasonable hope for antibiotics to return a patient to a somew...
Source: Science - The Huffington Post - Category: Science Source Type: news
Today, the Boston Globe editorial board spoke out against a bill "that would require insurers in Massachusetts to cover Lyme disease treatments for as long as a doctor says they're needed." The Globe writes: Lawmakers may have good intentions, but they don't possess the expertise to decide whether it's beneficial, cost-efficient, or safe, to keep using strong medicines to treat a condition the medical establishment doubts is real. Such questions should be resolved by a consensus of doctors and researchers -- and buttressed by convincing clinical date [sic] -- not determined by legislative mandate. Who among the B...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Last week, I mentioned the case of Dr. Neil Spector, whose long-undiagnosed Lyme Disease resulted in irreversible heart failure and ultimately, a heart transplant. Dr. Spector, author of Gone in a Heartbeat: A Physician's Search for True Healing, is the Sandra Coates Associate Professor of Medicine and Associate Professor of Pharmacology and Cancer Biology at Duke University School of Medicine. As the Director of Developmental Therapeutics at the Duke Cancer Institute, he's a leader in applying translational research to the clinical development of molecularly targeted personalized cancer therapies. Here, Dr. Spector share...
Source: Science - The Huffington Post - Category: Science Source Type: news
Tara and David Geraghty On Dec. 22, three days before Christmas, 55-year-old David A. Geraghty died from complications of a supposedly rarely fatal infection: Lyme disease. As reported in The Valley Breeze, a Lincoln, R.I. newspaper, Geraghty and his family found out conclusively that he has had Lyme disease just one year ago, last December. As was the case for me and is not uncommon in other cases of Lyme disease diagnoses, it was Geraghty and his wife -- not his physicians -- who pushed for investigation into the cause of his illness and ultimately were responsible for discovering that Lyme disease was at the root. Gerag...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
This article describes a cluster of cases of Chagas disease among a single family, which was discovered on screening after two affected members of the family donated blood. The current state of screening programs for Trypanosoma cruzi are discussed, and suggestions for future directions are included. Parents? and adolescents? willingness to be vaccinated against serogroup B meningococcal disease during a mass vaccination in Saguenay?Lac-St-Jean (Quebec)Since the implementation of the meningococcal C conjugate vaccine as a component of the routine vaccination schedule of children in Quebec, the incidence of meningitis cause...
Source: Canadian Journal of Infectious Diseases and Medical Microbiology - Category: Infectious Diseases Source Type: research
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