Fight Aging! Newsletter, July 29th 2019

In this study we show, for the first time, significant alterations in cholesterol efflux capacity in adolescents throughout the range of BMI, a relationship between six circulating adipocyte-derived EVs microRNAs targeting ABCA1 and cholesterol efflux capacity, and in vitro alterations of cholesterol efflux in macrophages exposed to visceral adipose tissue adipocyte-derived EVs acquired from human subjects. These results suggest that adipocyte-derived EVs, and their microRNA content, may play a critical role in the early pathological development of ASCVD. Commentary on the Developing UK Government Position on Healthy Longevity https://www.fightaging.org/archives/2019/07/commentary-on-the-developing-uk-government-position-on-healthy-longevity/ One option for patient advocacy for the treatment of aging as a medical condition is to petition governments and large international organizations such as the World Health Organization to adjust their positions on research funding and goals in medicine. This a fairly popular path, for all that I think it not terribly effective at speeding up the cutting edge of research and development. Large organizations of any sort are inherently conservative, and tend to get meaningfully involved in new fields of human endeavor only long after their support would have been truly influential. Nonetheless, numerous examples of government focused initiatives have emerged from our community over the past decade. They include the...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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Publication date: Available online 3 July 2020Source: The Annals of Thoracic SurgeryAuthor(s): Vignesh Raman, Oliver K. Jawitz, Soraya L. Voigt, Kristen E. Rhodin, Anthony W. Kim, Betty C. Tong, Thomas A. D’Amico, David H. Harpole
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Publication date: Available online 3 July 2020Source: The Annals of Thoracic SurgeryAuthor(s): Jun-Feng Wang, Can-Qiong Tian, Qiang-Bo Kan
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Publication date: Available online 2 July 2020Source: Artificial Intelligence in MedicineAuthor(s): Jacques Bouaud, Sylvia Pelayo, Jean-Baptiste Lamy, Coralie Prebet, Charlotte Ngo, Luis Teixeira, Gilles Guézennec, Brigitte Seroussi
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
Conclusions: Operative laparoscopy under conscious sedation and local anesthesia appears to be a feasible technique in gynecologic surgery with no adverse patient outcomes. PMID: 32612345 [PubMed - in process]
Source: JSLS : Journal of the Society of Laparoendoscopic Surgeons - Category: Surgery Tags: JSLS Source Type: research
Conclusion: Upper gastrointestinal pathology is highly common in patients with obesity. There is a significant rate of clinically significant endoscopy findings and all bariatric surgery patients should undergo preoperative endoscopy. PMID: 32612344 [PubMed - in process]
Source: JSLS : Journal of the Society of Laparoendoscopic Surgeons - Category: Surgery Tags: JSLS Source Type: research
CONCLUSION: recommendations emphasize isolation, proper rest, sleep, nutrition, hydration, medications, and in the more severe cases, oxygen support, monitoring of vital signs, emotional support, and multiprofessional and individualized care. Medications should be used with caution due to a lack of evidence. Future research is needed to analyze the impact of the infection at the beginning of pregnancy and the psychological aspects of pregnant women infected with the virus. PMID: 32609284 [PubMed - in process]
Source: Revista Latino-Americana de Enfermagem - Category: Nursing Authors: Tags: Rev Lat Am Enfermagem Source Type: research
CONCLUSION: it became evident that palliative care in primary health care has been gradually developed, but it is necessary to consider the organization of primary health care and the social policies that support or weaken it, being considered a complex challenge. PMID: 32609270 [PubMed - in process]
Source: Revista Latino-Americana de Enfermagem - Category: Nursing Authors: Tags: Rev Lat Am Enfermagem Source Type: research
CONCLUSION: low-cost, handmade simulators are feasible and effective, resulting in positive learner evaluations. Their availability as open technology allows the dissemination of their use. PMID: 32609265 [PubMed - in process]
Source: Revista Latino-Americana de Enfermagem - Category: Nursing Authors: Tags: Rev Lat Am Enfermagem Source Type: research
Publication date: Available online 24 June 2020Source: Saudi Journal of Biological SciencesAuthor(s): Neda M. Bogari, Ashwag Aljohani, Anas Dannoun, Osama Elkhateeb, Masimo Porqueddu, Amr A. Amin, Dema N. Bogari, Mohiuddin M. Taher, Faruk Buba, Reem M. Allam, Mustafa N. Bogari, Francesco Alamanni
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Publication date: Available online 3 July 2020Source: Redox BiologyAuthor(s): Jyotirindra Maity, Moonmoon Deb, Carl Greene, Hiranmoy Das
Source: Redox Biology - Category: Biology Source Type: research
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