And now for some good news on health
When it comes to health concerns, the COVID-19 pandemic is top of mind for most people right now. And that’s for good reason. But there is some very good non-COVID health news that may not be getting the attention it deserves. According to the CDC, the rates of six of the top 10 causes of death in this country, which account for about three-quarters of all deaths, have been declining. That’s remarkable. And these improvements are occurring despite an aging population and an obesity epidemic that affects several health conditions. Six positive health trends Let’s look at the trends in these conditions and their rank ...
Source: Harvard Health Blog - May 15, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Cancer Health Health trends Heart Health Source Type: blogs

Mortality in hypertrophic cardiomyopathy – Cardiology MCQ – Answer
Mortality in hypertrophic cardiomyopathy – Cardiology MCQ – Answer Disease specific mortality in hypertrophic cardiomyopathy –  Correct answer: a) 0.5% per year Hypertrophic cardiomyopathy (HCM) is the commonest among heritable heart diseases, with prevalence of about one in 500 individuals [1]. HCM is often highlighted as the leading cause of sudden death in young adults and athletes [2]. Still the absolute annual mortality in HCM is not high with availability of current treatment modalities including the implantation of cardioverter-defibrillator to prevent sudden death. It has been reported t...
Source: Cardiophile MD - April 19, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

Patients & Vulnerable Populations Pandemically Left in the Dark
By GRACE CORDOVANO PhD, BCPA To be honest, the United States blew it on the mask front. From a public health, caregiver and patient safety, as well as community transmission standpoint, we are at least 3 months late to game. Anytime a brand new virus that humanity does not have any immunity to makes an appearance, is highly contagious, starts rapidly infecting people as well as the doctors and nurses caring for them, hospitalizing, and killing them in concerning numbers across the globe, we should enable every proactive safety measure at our disposal. The first confirmed case of COVID-19 in the US was on January 20,...
Source: The Health Care Blog - April 7, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy coronavirus Grace Cordovano masks Pandemic Source Type: blogs

OK, boomer: You ’re not the only one who needs testing for hepatitis C
It turns out that many more people than just boomers can benefit from testing for hepatitis C, a viral infection of the liver that often causes no symptoms. If you’re a member of the baby-boom generation (born between 1946 and 1964), your doctor may have already recommended the test. But those born before or after those years may not have known about the test unless they had a risk factor for hepatitis C, such as a history of intravenous drug use. A new guideline is changing this approach. Why the different recommendations for baby boomers? In 2012–2013, the CDC and the US Preventive Services Task Force (USPSTF) establ...
Source: Harvard Health Blog - March 31, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Digestive Disorders Health Infectious diseases Men's Health Sexual Conditions Women's Health Source Type: blogs

Fight Aging! Newsletter, February 10th 2020
In conclusion, the concept of an epigenetic clock is compelling, but caution should be taken in interpreting associations with age acceleration. Association tests of age acceleration should include age as a covariate. A Discussion of Recent Work on Allotopic Expression of Mitochondrial Genes at the SENS Research Foundation https://www.fightaging.org/archives/2020/02/a-discussion-of-recent-work-on-allotopic-expression-of-mitochondrial-genes-at-the-sens-research-foundation/ A paper published last month outlines recent progress on allotopic expression of mitochondrial genes carried out by the SENS Research...
Source: Fight Aging! - February 9, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, December 23rd 2019
In this study, by adenovirus-mediated delivery and inducible transgenic mouse models, we demonstrate the proliferation of both HCs and SCs by combined Notch1 and Myc activation in in vitro and in vivo inner ear adult mouse models. These proliferating mature SCs and HCs maintain their respective identities. Moreover, when presented with HC induction signals, reprogrammed adult SCs transdifferentiate into HC-like cells both in vitro and in vivo. Finally, our data suggest that regenerated HC-like cells likely possess functional transduction channels and are able to form connections with adult auditory neurons. Epige...
Source: Fight Aging! - December 22, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, December 9th 2019
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - December 8, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Tryptophan Metabolism and Inflammaging
Today's open access research on tryptophan and its role in age-related immune dysfunction is particularly interesting in the context of ongoing research into the changes that take place in gut microbiota with age. Other recent work has examined the way in which tryptophan production by gut microbes declines precipitously with age, as this is one of a number of compounds produced by bacteria, such as butyrate, indole, and proprionate, that are influential on long term health. It is a slow process, but researchers are uncovering the specific mechanisms linking age-related changes in gut microbe populations with declining hea...
Source: Fight Aging! - December 6, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

HPV and cancer: The underappreciated connection
Did you know that a viral infection can lead to a number of different types of cancer? If that comes as a surprise to you, you’re not alone. In fact, according to a new study, many people have no idea that a common viral infection called human papilloma virus (HPV) can cause cancer of the genitals, anus, mouth, and throat, as well as cervical cancer. Viral infections and cancer The connection between certain viral infections and cancer has been recognized for many years. Some of the most well-established examples include hepatitis C, human immunodeficiency virus (HIV), and human papillomavirus (HPV). One thing these viru...
Source: Harvard Health Blog - November 8, 2019 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Adolescent health Cancer Infectious diseases Men's Health Sexual Conditions Vaccines Women's Health Source Type: blogs

Fight Aging! Newsletter, October 21st 2019
In this study, AT1-AAs were detected in the sera of patients with peripheral arterial disease (PAD) and the positive rate was 44.44% vs. 17.46% in non-PAD volunteers. In addition, analysis showed that AT1-AAs level was positively correlated with PAD. To reveal the causal relationship between AT1-AAs and vascular aging, an AT1-AAs-positive rat model was established by active immunization. The carotid pulse wave velocity was higher, and the aortic endothelium-dependent vasodilatation was attenuated significantly in the immunized rats. Morphological staining showed thickening of the aortic wall. Histological examination showe...
Source: Fight Aging! - October 20, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Can vaping damage your lungs? What we do (and don ’t) know
The rising popularity of vaping has been dramatic, especially among teenagers. According to a recent study, about 37% of high school seniors reported vaping in 2018, up from 28% the year before. An estimated 2.1 million middle school and high school students reported using e-cigarettes in 2017; that number jumped to 3.6 million in 2018. Certainly, age restrictions — it’s illegal to sell e-cigarettes to anyone under 21 (18 or 19 in some states) — aren’t preventing use among teens and young adults. And nearly seven million adults 18 or older use e-cigarettes, according to a 2017 survey by the CDC. E-cigarettes use a ...
Source: Harvard Health Blog - September 4, 2019 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Addiction Adolescent health Lung disease Men's Health Smoking cessation Women's Health Source Type: blogs

Inside Schizophrenia: Families Impacted by Schizophrenia
 Schizophrenia does not just affect the person with schizophrenia, but their families, also. This episode of Inside Schizophrenia explores the family relationships impacted by schizophrenia, both immediate and extended.  Two guests join us. The first is Chrisa Hickey, who is the mother of an adult son with schizophrenia and started an online site for parents of children who have a severe mental illness. The other guest, interviewed by co-host Gabe Howard, is Janel Star Withers, mother of host Rachel Star Withers. Janel shares her experiences with raising a schizophrenic daughter.  Host Rachel Star Withers, a diagnosed...
Source: World of Psychology - August 21, 2019 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: Children and Teens Family Inside Schizophrenia Parenting Bipolar disorder and schizophrenia Family Mental Health family mental illness Helping Families in Mental Health Crisis life with schizophrenia Mental Disorder Mental illness and Source Type: blogs

Families Impacted by Schizophrenia
  Schizophrenia does not just affect the person with schizophrenia, but their families, also. This episode of Inside Schizophrenia explores the family relationships impacted by schizophrenia, both immediate and extended.  Two guests join us. The first is Chrisa Hickey, who is the mother of an adult son with schizophrenia and started an online site for parents of children who have a severe mental illness. The other guest, interviewed by co-host Gabe Howard, is Janel Star Withers, mother of host Rachel Star Withers. Janel shares her experiences with raising a schizophrenic daughter.  Host Rachel Star Withers, a diagno...
Source: World of Psychology - August 21, 2019 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: Children and Teens Family General Inside Schizophrenia Mental Health and Wellness Parenting Bipolar disorder and schizophrenia Family Mental Health family mental illness Helping Families in Mental Health Crisis life with schizophrenia Source Type: blogs

Fight Aging! Newsletter, July 15th 2019
In conclusion, we show here that sEVs are responsible for mediating paracrine senescence and speculate that they could be involved in inducing bystander senescence during therapy-induced senescence or aging. In fact, when compared to soluble factors, sEVs have different biophysical and biochemical properties as they have a longer lifespan than do soluble factors and they are more resistant to protease degradation. The idea that blocking sEV secretion could be a potential therapeutic approach to alleviate senescence "spreading" during chemotherapy-induced senescence or in aging tissues presents itself as a very attractive t...
Source: Fight Aging! - July 14, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, May 20th 2019
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - May 19, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs