Fight Aging! Newsletter, May 28th 2018
This study indicates that frailty and other age-related diseases could be prevented and significantly reduced in older adults. Getting our heart risk factors under control could lead to much healthier old ages. Unfortunately, the current obesity epidemic is moving the older population in the wrong direction, however our study underlines how even small reductions in risk are worthwhile." The study analysed data from more than 421,000 people aged 60-69 in both GP medical records and in the UK Biobank research study. Participants were followed up over ten years.
The researchers analysed six factors that could impact on...
Source: Fight Aging! - May 27, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Senescent T Cells as a Contributing Cause of Age-Related Autoimmunity
We reported that a unique PD-1+ MP CD4+ T cell population is increased with age, now termed senescence-associated (SA-) T cells. The SA-T cells show characteristic signs and features of cellular senescence and emerge as follicular T cells in spontaneous germinal centers (GCs) that occur in aged mice. Spontaneous development of GCs is a hallmark of systemic autoimmune diseases, and among a number of changes in immune function with age is an increasing risk for autoimmunity.
Link: https://www.ncbi.nlm.nih.gov/books/NBK500331/ (Source: Fight Aging!)
Source: Fight Aging! - May 25, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Will Cancer Drugs Ever Be As Affordable As Retrovirals in Low and Middle Income Countries?
By ASHLEY ANDREOU
In 2014, the majority of international health aid was dedicated to HIV. So, one might reasonably assume that this is the largest health problem facing the world. Yet, HIV only constitutes 4% of the global burden of disease. In 2014, noncommunicable diseases (NCDs) made up 50% of the entire disease burden, but only received 2% of all global health funds.
The disease burden of NCDs is fast outpacing that of infectious diseases. Despite this, the proportion of global health financing dedicated to combatting NCDs has remained constant over the past 15 years at 1 to 2%.
Currently, 32.6 million individuals are...
Source: The Health Care Blog - May 17, 2018 Category: Consumer Health News Authors: Matthew Holt Tags: OP-ED Biologic generics Cancer Pharmaceuitcals Retrovirals Source Type: blogs
Will Cancer Drugs Ever Be As Affordable As Retrovirals in Developing Countries?
By ASHLEY ANDREOU
In 2014, the majority of international health aid was dedicated to HIV. So, one might reasonably assume that this is the largest health problem facing the world. Yet, HIV only constitutes 4% of the global burden of disease. In 2014, noncommunicable diseases (NCDs) made up 50% of the entire disease burden, but only received 2% of all global health funds.
The disease burden of NCDs is fast outpacing that of infectious diseases. Despite this, the proportion of global health financing dedicated to combatting NCDs has remained constant over the past 15 years at 1 to 2%.
Currently, 32.6 million individuals are...
Source: The Health Care Blog - May 17, 2018 Category: Consumer Health News Authors: Matthew Holt Tags: OP-ED Biologic generics Cancer Pharmaceuitcals Retrovirals Source Type: blogs
Fight Aging! Newsletter, May 14th 2018
This study found that professional chess players had shorter lifespans than those players who had careers outside of chess and argued that this might be due to the mental strain of international chess competition.
In the present study, we focused on survival of International Chess Grandmasters (GMs) which represent players, of whom most are professional, at the highest level. In 2010, the overall life expectancy of GMs at the age of 30 years was 53.6 years, which is significantly greater than the overall weighted mean life expectancy of 45.9 years for the general population. In all three regions examined, mean life...
Source: Fight Aging! - May 13, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Mr. and Mrs. Wheat Belly
Men and women follow the Wheat Belly lifestyle and can undergo important and sometime startling hormonal changes. Though results vary with stage of life—young adults, middle-aged, older—there are a variety of hormonal changes that women and men typically experience, some in concert, others independently. Such hormonal shifts can be powerful and part of the health-restoring menu of changes that develop with this lifestyle. They can even improve a relationship in a number of ways, both physically and emotionally, especially if we weave in some of the newer Wheat Belly/Undoctored concepts and practices such as oxy...
Source: Wheat Belly Blog - March 13, 2018 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle estradiol estrogen hormonal hormones Inflammation low-carb oxytocin testosterone Thyroid Weight Loss Source Type: blogs
High Levels of Physical Activity Prevent Several Aspects of Immunosenescence
We examined 125 male and female cyclists, aged 55 to 79, who had maintained a high level of cycling throughout most of their adult lives. These were not Olympians, but very keen cyclists who were able to cycle 100km in under 6.5 hours for the men, and 60km in under 5.5 hours for the women. At mid-life, people start losing muscle mass and strength at a rate of 1% to 2% per year, making it harder to carry out their normal activities such as climbing stairs. Our bones also become thinner with age and this can eventually lead to diseases such as osteoporosis. We showed that the cyclists did not lose muscle mass or strength as ...
Source: Fight Aging! - March 8, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
National Academy of Sciences Report on Electronic Cigarettes Confirms that Vaping is Much Safer than Smoking and Has No Known Long-Term Health Effects
My commentary on the conclusions and implications of the National Academy of Sciences report on electronic cigarettes was just accepted as an op-ed piece in U.S. News& World Report. I expect it to be published tomorrow. For this reason, I have had to take down the original commentary. However, below I have posted the parts of the original blog post that had to be cut from the op-ed because of length concerns. Also, I will post a link to the op-ed as soon as it appears.The key findings of the report are:1. " There is substantial evidence that except for nicotine, under typical conditions of use, exposure to potentially ...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - January 24, 2018 Category: Addiction Source Type: blogs
National Academy of Sciences Report on E-Cigarettes Confirms that Vaping is Much Safer than Smoking and Has No Known Long-Term Health Effects
Areport released this morning by the National Academy of Sciences confirms that despite the demonization of vaping by many anti-tobacco groups and health departments, use of these products is much safer than smoking, and there are no known long-term health effects associated with vaping.This does not mean, of course, that vaping is safe. It just means that we don ' t know what the long-term effects may be. But it is important to stress that at this time, we don ' t know of any long-term adverse health effects.The report also concludes that the " second-hand " aerosol produced by vaping is safer than secondhand tobacco smok...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - January 23, 2018 Category: Addiction Source Type: blogs
Fight Aging! Newsletter, December 25th 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - December 24, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Young Adult Ignored Cancer Patients
This is one of my pet peeves. Children with cancer have their mature, sane parents advocating for them. Adults with cancer can advocate for themselves.The young adults - 15 to 30s - often don ' t find the same support or resources. First they are still trying to figure out who they are and what they will do with their life. Second, they are learning to be independent and should be focusing on their education and careers, not going to chemotherapy. There is hope now that online resources can help fill the gaps for the patients and maybe for the doctors as well." In addition, they will probably go on to live long lives and t...
Source: Caroline's Breast Cancer Blog - December 22, 2017 Category: Cancer & Oncology Tags: cancer bonds cancer treatment side effects young cancer patients Source Type: blogs
NYTimes: The Growing Toll of Our Ever-Expanding Waistlines
The Growing Toll of Our Ever-Expanding WaistlinesBy JANE E. BRODY NOV. 13, 2017Paul Rogers I hope you ’re not chomping on a bagel or, worse, a doughnut while you read about what is probably the most serious public health irony of the last half century in this country: As one major killer — smoking — declined, another rose precipitously to take its place: obesity.Many cancer deaths were averted after millions quit lighting up, but they are now rising because even greater numbers are unable to keep their waistlines in check.Today, obesity and smoking remain the two leading causes of preventable dea...
Source: Dr Portnay - November 13, 2017 Category: Cardiology Authors: Dr Portnay Source Type: blogs
Good news about the HPV vaccine
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Did you know certain viruses can cause cancer? Two common examples include hepatitis C (which is linked with liver cancer) and human papilloma virus (HPV, which causes cervical cancer). The discovery of these virus-cancer connections is particularly important, because if a vaccine can prevent these viral infections it may also prevent cancer. And there is preliminary evidence that the HPV vaccine is making this happen. More on that in a moment.
What is HPV?
HPV is a group of viruses that may cause warts (papillomas) and a variety of cancers, including those involving the throat, rectum, ...
Source: Harvard Health Blog - October 11, 2017 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Infectious diseases Prevention Sexual Conditions Vaccines Source Type: blogs
Fight Aging! Newsletter, August 21st 2017
This study didn't measure whether receiving the cardiosphere-derived cells extended lifespans, so we have a lot more work to do. We have much to study, including whether CDCs need to come from a young donor to have the same rejuvenating effects and whether the extracellular vesicles are able to reproduce all the rejuvenating effects we detect with CDCs."
Cardiac and systemic rejuvenation after cardiosphere-derived cell therapy in senescent rats
Cardiosphere-derived cell (CDC) therapy has exhibited several favourable effects on heart structure and function in humans and in preclinical models; however, the ...
Source: Fight Aging! - August 20, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
More Than 1 Million Young Caregivers Live In the United States, But Policies Supporting Them Are Still ‘Emerging’
Being a family caregiver today is a demanding responsibility. If caregiving is stressful for the “typical” caregiver—a 49-year-old woman—think how much more is at stake when the caregiver is a child or teenager. Yet more than a million youngsters ages 8–18 take on challenging tasks to help a parent, grandparent, sibling, or other relative. While that number is undoubtedly an underestimate, it does not even include an emerging subgroup—children whose parents are struggling with opioid addiction.
If we have limited information about the young people taking care of those with diabetes, cancer, and ...
Source: Health Affairs Blog - August 7, 2017 Category: Health Management Authors: Carol Levine Tags: Featured Population Health Public Health Quality Agnes Leu child caregivers family caregivers National Alliance for Caregiving Saul Becker United Hospital Fund Source Type: blogs
