Fight Aging! Newsletter, May 20th 2019
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is published under the Creative Commons Attribution 4.0 International License. You are encouraged to republish and rewrite it in any way you see fit, the only requirements being that you provide attribution and a link to Fight Aging! To subscribe or unsubscribe please visit: https://www.fightaging.org/newsletter/ Contents The Goal of Fixing the Power Plants of the Cell Anethole Trithione is a Mitochondrial ROS Blocker Towards Restoration of Neural Stem Cell Function in the Old Poor Sense of Smell Correlates with Increased Mortality in Older Individuals Is α-synuclein, Like Tau, Driven to Aggregate by the Activities of Inflammatory Microglia? Unity Biotechnology's Locally Administered Senolytic Trials MicroRNA-199 Produces Significant Heart Regeneration in Pigs Evidence for the Mutation Accumulation Hypothesis of the Ori...
ConclusionsPamidronate is a safe and efficient method of CRMO therapy, particularly in cases refractory to NSAIDs treatment. Treatment with pamidronate provides both symptomatic relief as well as normalisation of bone morphology.
Publication date: Available online 16 June 2019Source: Joint Bone SpineAuthor(s): Pierre Letellier, Florian Bailly, Marina Assadourian, Antoine Potel, Violaine Foltz, Sophia Ascione, Laetitia Morardet, Myrianne Le Ralle, Bruno Fautrel, Arnaud Dupeyron, Nada Ibrahim-Nasser, Isabelle Griffoul-Espitalier, Bernard Duplan, Johann Beaudreuil, Laure Gossec
Pfizer has agreed to buy Array Biopharma in a $10.64 billion cash deal.
As researchers continue to hunt for ways to treat or prevent Alzheimer ’s disease, one study has shown promise in slowing the progression of the disease.
Cardiovascular disease (CVD) is often caused by modifiable risk factors related to diet and lifestyle behaviors. Counseling patients to adopt lifestyle changes for CVD risk-reduction is needed. Using the 5As strategy (ask, assess, advise, agree, assist) can help patients incorporate positive behavior changes and reduce CVD risk factors.
In this study, it is seen that kefir has positive effects on sleep disturbances, depression, and quality of life in postmenopausal women.
Nearly 6% of people in the study had a heart attack otrdeveloped angina (chest pain). The researchers found that all the people who developed heart trouble displayed a faster decline in their mental function at the same time.
ConclusionsPatients with PD and LIDs have abnormal cortical facilitation, possibly suggesting overactive glutamatergic neurotransmission in specific circuits within M1. Although not responsive to l-dopa, this dysfunction is restored by the anti-glutamatergic properties of safinamide 100 mg. The results suggest that the abnormal cortical facilitation in M1 contributes to the pathophysiology of LIDs.
Circadian rhythm disturbances in older adults may be markers of Alzheimer disease and its progression, new research suggests.Medscape Medical News
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