The paradox of spring: Thyroid and glucocorticoid responses to cold temperatures and food availability in free living Carneddau ponies
Horm Behav. 2024 Mar 18;161:105526. doi: 10.1016/j.yhbeh.2024.105526. Online ahead of print.ABSTRACTIn seasonal environments, maintaining a constant body temperature poses challenges for endotherms. Cold winters at high latitudes, with limited food availability, create opposing demands on metabolism: upregulation preserves body temperature but depletes energy reserves. Examining endocrine profiles, such as thyroid hormone triiodothyronine (T3) and glucocorticoids (GCs), proxies for changes in metabolic rate and acute stressors, offer insights into physiological trade-offs. We evaluated how environmental conditions and gest...
Source: Hormones and Behavior - March 19, 2024 Category: Endocrinology Authors: Jessica Granweiler Jurgi Crist óbal-Azkarate Nathan Morton Rupert Palme Susanne Shultz Source Type: research
The paradox of spring: Thyroid and glucocorticoid responses to cold temperatures and food availability in free living Carneddau ponies
Horm Behav. 2024 Mar 18;161:105526. doi: 10.1016/j.yhbeh.2024.105526. Online ahead of print.ABSTRACTIn seasonal environments, maintaining a constant body temperature poses challenges for endotherms. Cold winters at high latitudes, with limited food availability, create opposing demands on metabolism: upregulation preserves body temperature but depletes energy reserves. Examining endocrine profiles, such as thyroid hormone triiodothyronine (T3) and glucocorticoids (GCs), proxies for changes in metabolic rate and acute stressors, offer insights into physiological trade-offs. We evaluated how environmental conditions and gest...
Source: Hormones and Behavior - March 19, 2024 Category: Endocrinology Authors: Jessica Granweiler Jurgi Crist óbal-Azkarate Nathan Morton Rupert Palme Susanne Shultz Source Type: research
Beyond Tourism: The Importance of Baby Boomer Generation Volunteers
AbstractPopulation aging is regarded as a dominant global demographic trend. One of the least researched population cohort groups in the past are older tourists, who are regarded as a lucrative target market by many volunteer tourism organizations. This systematic literature review provides an analysis of the existing literature and concludes that even though numerous studies have shown the benefits of volunteering for older adults ’ health and well-being, there have been relatively few academic studies that have examined older adult’s (including the baby boomer generation) experiences as volunteer tourists and their e...
Source: Journal of Population Ageing - March 19, 2024 Category: International Medicine & Public Health Source Type: research
NASA ’s x-ray telescope faces a long goodbye
The end is nigh for NASA’s nearly 25-year-old Chandra X-ray Observatory. Funding for the space telescope was slashed last week in President Joe Biden’s budget request, which calls for winding the mission down over several years.
Astronomers are up in arms over the announcement. They argue that the telescope is as productive as ever and remains a cornerstone of U.S. high-energy astrophysics. Its loss would be an “extinction-level event” for x-ray astronomy in the United States, according to a “
SaveChandra
” website set up to lobby for the mission.
“I’m horrified by the prospect of Chan...
Source: Science of Aging Knowledge Environment - March 18, 2024 Category: Geriatrics Source Type: research
Budget impact analyses for treatment of heart failure. A systematic review
This study aims to systemically review the budget impact analysis of heart failure treatments on health care expenditure worldwide. Scientific databases such as PubMed, Web of Science, Scopus, and Google Scholar were searched for budget impact analysis and heart failure treatments, over January 2001 to August 2023. The quality assessment of the selected studies was evaluated through ISPOR practice guideline. Nineteen studies were included in this systematic review. Based on ISPOR recommendations, most studies were performed on a 1-year time horizon and used a government (public health) or health system perspective. Data...
Source: Heart Failure Reviews - March 16, 2024 Category: Cardiology Source Type: research
Abiotic Methane Production Driven by Ubiquitous Non-Fenton-Type Reactive Oxygen Species
Angew Chem Int Ed Engl. 2024 Mar 15:e202403884. doi: 10.1002/anie.202403884. Online ahead of print.ABSTRACTAbiotic CH4 production driven by Fenton-type reactive oxygen species (ROS) has been confirmed to be an indispensable component of the atmospheric CH4 budget. While the chemical reactions independent of Fenton chemistry to ROS are ubiquitous in nature, it remains unknown whether the produced ROS can drive abiotic CH4 production. Here, we first demonstrated the abiotic CH4 production at the soil-water interface under illumination. Leveraging this finding, polymeric carbon nitrides (CNx) as a typical analogue of natural ...
Source: Angewandte Chemie - March 15, 2024 Category: Chemistry Authors: Jie Ye Andong Hu Chao Gao Fengqi Li Lei Li Yulin Guo Guoping Ren Bing Li Christopher Rensing Kenneth H Nealson Shungui Zhou Yujie Xiong Source Type: research
How healthy is the health budget of < em > Amrit Kaal < /em > : 2023-24?
J Family Med Prim Care. 2024 Jan;13(1):5-9. doi: 10.4103/jfmpc.jfmpc_398_23. Epub 2024 Feb 8.ABSTRACTPolitical will is the key to public health policy-making and a major driving force for the attainment of Universal Health Coverage (UHC) in any nation. To achieve UHC, the Indian government laid down National Health Policy in 1983 and updated it in 2002 and recently in 2017. This recent policy emphasized increasing healthcare spending and economic growth. In the current budget, there is an increment in the share of GDP of 0.34% from the previous year's allocation, but still staggering for the envisaged 2.5% to achieve UHC. ...
Source: Primary Care - March 14, 2024 Category: Primary Care Authors: Madan M Majhi Anshita Mishra Suneela Garg Raman Kumar Source Type: research
Biden seeks to boost science funding — but his budget faces an ominous future
Nature, Published online: 12 March 2024; doi:10.1038/d41586-024-00340-0The US president proposes a 2025 budget even as negotiations continue over the 2024 budget. (Source: Nature AOP)
Source: Nature AOP - March 12, 2024 Category: Research Authors: Jeff Tollefson Max Kozlov Sumeet Kulkarni Mariana Lenharo Alexandra Witze Source Type: research
Zero budget natural farming components Jeevamrit and Beejamrit augment Spinacia oleracea L. (spinach) growth by ameliorating the negative impacts of the salt and drought stress
The growth of crop plants, particularly spinach (Spinacia oleracea L.), can be significantly impeded by salinity and drought. However, pre-treating spinach plants with traditional biofertilizers like Jeevamrit and Beejamrit (JB) substantially reverses the salinity and drought-induced inhibitory effects. Hence, this study aims to elucidate the underlying mechanisms that govern the efficacy of traditional fertilizers. The present work employed comprehensive biochemical, physiological, and molecular approaches to investigate the processes by which JB alleviates abiotic stress. The JB treatment effectively boosts spinach growt...
Source: Frontiers in Microbiology - March 12, 2024 Category: Microbiology Source Type: research
Simplifying stable CHO cell line generation with high probability of monoclonality by using microfluidic dispensing as an alternative to fluorescence activated cell sorting
AbstractSingle cell cloning is a critical step for cell line development (CLD) for therapeutic protein production, with proof of monoclonality being compulsorily sought in regulatory filings. Among the different single cell deposition technologies, we found that fluorescence activated cell sorting (FACS) offers high probability of monoclonality and can allow selective enrichment of the producer cells. However, FACS instruments are expensive and resource-intensive, have a large footprint, require highly skilled operators and take hours for setup, thereby complicating the cell line generation process. With the aim of finding...
Source: Biotechnology Progress - March 11, 2024 Category: Biotechnology Authors: Lina Chakrabarti,
James Savery,
John Patrick Mpindi,
Judith Klover,
Lina Li,
Jie Zhu Tags: RESEARCH ARTICLE Source Type: research
Is Economic Evaluation and Care Commissioning Focused on Achieving the Same Outcomes? Resource-Allocation Considerations and Challenges Using England as a Case Study
We describe considerations and challenges as to the practical role of relevant outcomes for evaluation and commissioning, seeking to bridge a gap between economic evaluation evidence and care commissioning. We describe conceptual (e.g., what are ‘relevant’ outcomes) alongside practical considerations (e.g., quantifying and using relevant endpoint or surrogate outcomes) and pertinent issues when linking outcomes to commissioning-based payment mechanisms, using England as a case study. Economic evaluation often focuses on a single endpoin t health-focused maximand, e.g., quality-adjusted life-years (QALYs), whereas commi...
Source: Applied Health Economics and Health Policy - March 11, 2024 Category: Health Management Source Type: research
Coral restoration can drive rapid reef carbonate budget recovery
Curr Biol. 2024 Feb 19:S0960-9822(24)00151-9. doi: 10.1016/j.cub.2024.02.009. Online ahead of print.ABSTRACTRestoration is increasingly seen as a necessary tool to reverse ecological decline across terrestrial and marine ecosystems.1,2 Considering the unprecedented loss of coral cover and associated reef ecosystem services, active coral restoration is gaining traction in local management strategies and has recently seen major increases in scale. However, the extent to which coral restoration may restore key reef functions is poorly understood.3,4 Carbonate budgets, defined as the balance between calcium carbonate productio...
Source: Current Biology - March 9, 2024 Category: Biology Authors: Ines D Lange Tries B Razak Chris T Perry Permas B Maulana Mochyudho E Prasetya None Irwan Timothy Ac Lamont Source Type: research
Coral restoration can drive rapid reef carbonate budget recovery
Curr Biol. 2024 Feb 19:S0960-9822(24)00151-9. doi: 10.1016/j.cub.2024.02.009. Online ahead of print.ABSTRACTRestoration is increasingly seen as a necessary tool to reverse ecological decline across terrestrial and marine ecosystems.1,2 Considering the unprecedented loss of coral cover and associated reef ecosystem services, active coral restoration is gaining traction in local management strategies and has recently seen major increases in scale. However, the extent to which coral restoration may restore key reef functions is poorly understood.3,4 Carbonate budgets, defined as the balance between calcium carbonate productio...
Source: Current Biology - March 9, 2024 Category: Biology Authors: Ines D Lange Tries B Razak Chris T Perry Permas B Maulana Mochyudho E Prasetya None Irwan Timothy Ac Lamont Source Type: research
Coral restoration can drive rapid reef carbonate budget recovery
Curr Biol. 2024 Feb 19:S0960-9822(24)00151-9. doi: 10.1016/j.cub.2024.02.009. Online ahead of print.ABSTRACTRestoration is increasingly seen as a necessary tool to reverse ecological decline across terrestrial and marine ecosystems.1,2 Considering the unprecedented loss of coral cover and associated reef ecosystem services, active coral restoration is gaining traction in local management strategies and has recently seen major increases in scale. However, the extent to which coral restoration may restore key reef functions is poorly understood.3,4 Carbonate budgets, defined as the balance between calcium carbonate productio...
Source: Current Biology - March 9, 2024 Category: Biology Authors: Ines D Lange Tries B Razak Chris T Perry Permas B Maulana Mochyudho E Prasetya None Irwan Timothy Ac Lamont Source Type: research
The emergence of the Medical University of Vienna 20 years ago
Wien Klin Wochenschr. 2024 Mar 8. doi: 10.1007/s00508-024-02334-4. Online ahead of print.ABSTRACTAt the beginning of the 2000s the Austrian public universities were characterized by staffing rigidities, little competitive research, outdated study curricula and free access to all fields of study, the latter combined with high dropout rates and long study durations. As a countermeasure the universities were granted full legal capacity. For new employees the status of civil servants was herewith cancelled and, being now subject to the Employment Act, tenured employments for anyone who wanted to stay at the university were no ...
Source: Wiener Klinische Wochenschrift - March 8, 2024 Category: General Medicine Authors: Wolfgang Sch ütz Markus Grimm Source Type: research
