Addressing radiotherapy-induced fibrosis: the potential of platelet-rich plasma and infliximab for improved breast cancer management
This study provides insights into optimizing outcomes i n reconstructive breast surgery, paving the way for further research and clinical studies. (Source: Histochemistry and Cell Biology)
Source: Histochemistry and Cell Biology - January 28, 2024 Category: Biomedical Science Source Type: research
Prognostic analysis of cT1-3N1M0 breast cancer patients who have responded to neoadjuvant therapy undergoing various axillary surgery and breast surgery based on propensity score matching and competitive risk model
ConclusionFor cN1+ breast cancer patients who respond positive to NAT, the optimal surgical approach is combining breast-conserving surgery (BCS) with SLNB. This procedure improves quality of life and long-term survival outcomes. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - January 24, 2024 Category: Cancer & Oncology Source Type: research
Optimizing surgical strategy in locally advanced breast cancer: a comparative analysis between preoperative MRI and postoperative pathology after neoadjuvant chemotherapy
ConclusionHER2 + and ER−/HER2− tumor subtypes showed clear correlation and agreement between preoperative MRI and postoperative pathological assessment of tumor size. This suggests that MRI evaluation could be a suitable predictor to guide the surgical approach. Conversely, correlation and agreement for E R + /HER2− and lobular tumors was poor, evidenced by a difference in tumor size of up to 5 cm. Hence, we demonstrate that histological tumor subtype should be taken into account when planning breast conserving surgery after NAC. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - January 23, 2024 Category: Cancer & Oncology Source Type: research
Pain Levels Following Cosmetic Breast Surgery and An Easy-To-Use Pain Treatment Algorithm for Plastic Surgeons
ConclusionsSubpectoral breast augmentation is associated with higher levels of postoperative pain compared to breast reduction and mastopexy. Effective postoperative pain prevention is crucial following aesthetic breast surgeries. It not only helps to reduce hospital stays but also aids in patient recovery, facilitates a quicker return to daily activities, and enhances patient satisfaction. To achieve this objective, it is advantageous to utilize a practical pain treatment algorithm that is readily applicable.Level of Evidence IIIThis journal requires that authors assign a level of evidence to each article. For a full desc...
Source: Aesthetic Plastic Surgery - January 19, 2024 Category: Cosmetic Surgery Source Type: research
Cancers, Vol. 16, Pages 419: Dkk1 as a Prognostic Marker for Neoadjuvant Chemotherapy Response in Breast Cancer Patients
Conclusions: In this study, we demonstrated for the first time that Dkk1 could be identified as an independent predictor of NACT response in BC patients, particularly those with TNBC. Further research with a multicentric expanded (pre-/post-therapy) sample set and better-defined populations in terms of molecular subtypes, therapy modality, and long-term follow-up is recommended to obtain more solid evidence. (Source: Cancers)
Source: Cancers - January 18, 2024 Category: Cancer & Oncology Authors: Kasoha Steinbach Bohle Linxweiler Haj Hamoud Doerk Nigdelis Stotz Zimmermann Solomayer Kaya Radosa Tags: Article Source Type: research
Adjuvant medial versus entire supraclavicular lymph node irradiation in high-risk early breast cancer (SUCLANODE): a protocol for a multicenter, randomized, open-label, phase 3 trial
Supraclavicular nodal (SCL) irradiation is commonly used for patients with high-risk breast cancer after breast surgery. The Radiation Therapy Oncology Group (RTOG) and European Society for Radiotherapy and On... (Source: BMC Cancer)
Source: BMC Cancer - January 9, 2024 Category: Cancer & Oncology Authors: Li Zhang, Xin Mei, Zhigang Hu, Bo Yu, Chaoyang Zhang, Yong Li, Kaitai Liu, Xuejun Ma, Jinli Ma, Xingxing Chen, Jin Meng, Wei Shi, Xiaofang Wang, Miao Mo, Zhimin Shao, Zhen Zhang & hellip; Tags: Study Protocol Source Type: research
Breast cancer in pregnancy: concurrent cesarean section, nipple-sparing mastectomy, and immediate breast reconstruction —case report
ConclusionTo the best of our knowledge, this is the first reported case of concomitant cesarean delivery, PABC mastectomy, axillary dissection, and IBR. This surgical strategy allowed PABC treatment by the BC guideline, minimizing the newborn’s disadvantage and permitting, at the same time, the best final BR outcome. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - January 8, 2024 Category: Cancer & Oncology Source Type: research
Breast surgery after neoadjuvant chemotherapy in patients with lobular carcinoma: surgical and oncologic outcome
ConclusionAlthough 33% of ILC breast cancer patients undergoing BCS after NAC required re-excision for positive resection margins, it is considered safe given that five-year RFS remained excellent and LRR and OS did not differ by extent of surgery. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - January 8, 2024 Category: Cancer & Oncology Source Type: research
Ruptured breast implant removal because of patient anxiety in the absence of breast implant-associated anaplastic large cell lymphoma
We report a case in which BIA-ALCL and breast cancer were not detected preoperatively, with subsequent removal of a ruptured breast implant. A 52-year-old woman had silicone breast implants on both sides for breast augmentation 15 years ago. Right axillary lymphadenopathy and intracapsular ruptures were noted by magnetic resonance imaging. Right axillary lymph node biopsy was performed at our department of breast surgery. Flow cytometry for BIA-ALCL was also performed using the exudate around the implant. The results were negative for breast cancer and BIA-ALCL. However, taking into consideration exacerbation of breast imp...
Source: Nagoya Journal of Medical Science - December 29, 2023 Category: International Medicine & Public Health Authors: Hitomi Takahashi Hideyoshi Sato Yukiyo Tsunekawa Urara Fujioka Yumi Wanifuchi-Endo Tatsuya Toyama Kazuhiro Toriyama Source Type: research
Immunohistochemical Evaluation of Perlecan (Heparan Sulphate Proteoglycan 2) Expression in Invasive Female Breast Carcinoma
CONCLUSION: Perlecan expression measured by immunohistochemical staining is associated with aggressive characteristics in breast cancer, suggesting that Perlecan may help in cancer progression and can be investigated as a possible target therapy.PMID:38156864 | DOI:10.31557/APJCP.2023.24.12.4277 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 29, 2023 Category: Cancer & Oncology Authors: Samar Ibrahim Amer Ismail Engy Talaat Helmy Ahmed Mahmoud Abdel Aziz Passant Essam Eldin Shibel Source Type: research
Ruptured breast implant removal because of patient anxiety in the absence of breast implant-associated anaplastic large cell lymphoma
We report a case in which BIA-ALCL and breast cancer were not detected preoperatively, with subsequent removal of a ruptured breast implant. A 52-year-old woman had silicone breast implants on both sides for breast augmentation 15 years ago. Right axillary lymphadenopathy and intracapsular ruptures were noted by magnetic resonance imaging. Right axillary lymph node biopsy was performed at our department of breast surgery. Flow cytometry for BIA-ALCL was also performed using the exudate around the implant. The results were negative for breast cancer and BIA-ALCL. However, taking into consideration exacerbation of breast imp...
Source: Nagoya Journal of Medical Science - December 29, 2023 Category: International Medicine & Public Health Authors: Hitomi Takahashi Hideyoshi Sato Yukiyo Tsunekawa Urara Fujioka Yumi Wanifuchi-Endo Tatsuya Toyama Kazuhiro Toriyama Source Type: research
Immunohistochemical Evaluation of Perlecan (Heparan Sulphate Proteoglycan 2) Expression in Invasive Female Breast Carcinoma
CONCLUSION: Perlecan expression measured by immunohistochemical staining is associated with aggressive characteristics in breast cancer, suggesting that Perlecan may help in cancer progression and can be investigated as a possible target therapy.PMID:38156864 | DOI:10.31557/APJCP.2023.24.12.4277 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 29, 2023 Category: Cancer & Oncology Authors: Samar Ibrahim Amer Ismail Engy Talaat Helmy Ahmed Mahmoud Abdel Aziz Passant Essam Eldin Shibel Source Type: research
