Pterostilbene alleviates cafeteria diet-induced obesity and underlying depression in adolescent male Swiss albino mice and affects insulin resistance, inflammation, HPA axis dysfunction and SIRT1 mediated leptin-ghrelin signaling
Horm Behav. 2024 Feb 13;161:105504. doi: 10.1016/j.yhbeh.2024.105504. Online ahead of print.ABSTRACTCafeteria diet (CD) model for in-vivo studies mimics the western diet having imbalanced nutritional value, high caloric-density and palatability. Uncontrolled eating leads to the development of childhood obesity, poor self-esteem and depression due to its effects on brain development. Herbal supplements are novel inclusion in the management of obesity and mental well-being. Pterostilbene (PTE) found in blueberries and Pterocarpus marsupium heartwood, is known to prevent obesity in invivo models. Adolescent Swiss albino male ...
Source: Hormones and Behavior - February 14, 2024 Category: Endocrinology Authors: Rashmi Patil Urmila Aswar Nishant Vyas Source Type: research
Pterostilbene alleviates cafeteria diet-induced obesity and underlying depression in adolescent male Swiss albino mice and affects insulin resistance, inflammation, HPA axis dysfunction and SIRT1 mediated leptin-ghrelin signaling
Horm Behav. 2024 Feb 13;161:105504. doi: 10.1016/j.yhbeh.2024.105504. Online ahead of print.ABSTRACTCafeteria diet (CD) model for in-vivo studies mimics the western diet having imbalanced nutritional value, high caloric-density and palatability. Uncontrolled eating leads to the development of childhood obesity, poor self-esteem and depression due to its effects on brain development. Herbal supplements are novel inclusion in the management of obesity and mental well-being. Pterostilbene (PTE) found in blueberries and Pterocarpus marsupium heartwood, is known to prevent obesity in invivo models. Adolescent Swiss albino male ...
Source: Hormones and Behavior - February 14, 2024 Category: Endocrinology Authors: Rashmi Patil Urmila Aswar Nishant Vyas Source Type: research
Pterostilbene alleviates cafeteria diet-induced obesity and underlying depression in adolescent male Swiss albino mice and affects insulin resistance, inflammation, HPA axis dysfunction and SIRT1 mediated leptin-ghrelin signaling
Horm Behav. 2024 Feb 13;161:105504. doi: 10.1016/j.yhbeh.2024.105504. Online ahead of print.ABSTRACTCafeteria diet (CD) model for in-vivo studies mimics the western diet having imbalanced nutritional value, high caloric-density and palatability. Uncontrolled eating leads to the development of childhood obesity, poor self-esteem and depression due to its effects on brain development. Herbal supplements are novel inclusion in the management of obesity and mental well-being. Pterostilbene (PTE) found in blueberries and Pterocarpus marsupium heartwood, is known to prevent obesity in invivo models. Adolescent Swiss albino male ...
Source: Hormones and Behavior - February 14, 2024 Category: Endocrinology Authors: Rashmi Patil Urmila Aswar Nishant Vyas Source Type: research
Molecules, Vol. 29, Pages 691: Targeted Anthocyanin Profiling of Fruits from Three Southern Highbush Blueberry Cultivars Propagated in Colombia
ra
The blueberry, a deciduous shrub in the Ericaceae family, is celebrated for its delightful flavor, sweetness, and abundance of anthocyanins and antioxidants, qualities that have garnered significant attention for their potential health benefits. Blueberries grown in diverse environments and exhibit varied anthocyanin profiles, often influenced by factors such as altitude and climate. Varietal groups worldwide have been bred and categorized based on their growth habits and specific cold requirements, particularly with southern highbush cultivars thriving in temperate climates, demonstrating tolerance to higher altitu...
Source: Molecules - February 2, 2024 Category: Chemistry Authors: Jessica Prada-Mu ñoz Ericsson Coy-Barrera Tags: Article Source Type: research
A biofertilizing fungal endophyte of cranberry plants suppresses the plant pathogen Diaporthe
Fungi colonizing plants are gaining attention because of their ability to promote plant growth and suppress pathogens. While most studies focus on endosymbionts from grasses and legumes, the large and diverse group of ericaceous plants has been much neglected. We recently described one of the very few fungal endophytes promoting the growth of the Ericaceae Vaccinium macrocarpon (American cranberry), notably the Codinaeella isolate EC4. Here, we show that EC4 also suppresses fungal pathogens, which makes it a promising endophyte for sustainable cranberry cultivation. By dual-culture assays on agar plates, we tested the pote...
Source: Frontiers in Microbiology - February 2, 2024 Category: Microbiology Source Type: research
©Relationship between endophytic fungal diversity and colonization and soil factors of cultured blueberry roots in Guizhou Province, Southwest China
In this study, four cultivars (Gardenblue, Powderblue, O'Neal, and Legacy) in three areas (Gaopo, Majiang, and Fenggang) in Guizhou were used to identify DSEs by morphological and molecular biological methods and to clarify the relationship between DSE diversity and DSE colonization and soil factors of cultivated blueberries in Guizhou. The DSEs isolated from cultivated blueberry roots in 3 areas in Guizhou Province were different, belonging to 17 genera, and the dominant genera were Penicillium, Phialocephala, and Thozetella. DSEs isolated from Majiang belonged to 12 genera and 16 species, those from Gaopo belonged to 7 g...
Source: Archives of Microbiology - February 1, 2024 Category: Microbiology Authors: Si Li Xiao-Jing Shang Rui Hou Source Type: research
Blueberry anthocyanins improve liver fibrosis by regulating NCOA4 ubiquitination through TRIM7 to affect ferroptosis of hepatic stellate cells
CONCLUSION: Our study discovered that anthocyanins could improve liver fibrosis by regulating NCOA4 ubiquitination through TRIM7, thereby affecting HSC ferroptosis levels.PMID:38290991 | DOI:10.1152/ajpgi.00227.2023 (Source: Am J Physiol Gastroi...)
Source: Am J Physiol Gastroi... - January 30, 2024 Category: Gastroenterology Authors: Likun Liu Jinhui Du Haiqing Fan Yue Yu Yilin Luo Fang Gu Hui Yu Xin Liao Source Type: research
Blueberry anthocyanins improve liver fibrosis by regulating NCOA4 ubiquitination through TRIM7 to affect ferroptosis of hepatic stellate cells
CONCLUSION: Our study discovered that anthocyanins could improve liver fibrosis by regulating NCOA4 ubiquitination through TRIM7, thereby affecting HSC ferroptosis levels.PMID:38290991 | DOI:10.1152/ajpgi.00227.2023 (Source: American Journal of Physiology. Gastrointestinal and Liver Physiology)
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - January 30, 2024 Category: Physiology Authors: Likun Liu Jinhui Du Haiqing Fan Yue Yu Yilin Luo Fang Gu Hui Yu Xin Liao Source Type: research
Gastrointestinal fate of blueberry anthocyanins in ferritin-based nanocarriers
This study aimed to evaluate the stability and absorption of blueberry anthocyanin extracts (BAE) and anthocyanin standards (malvidin and cyanidin glycosides) when encapsulated using ferritin (FR) nanocarriers or a combination of FR and sodium alginate (SA) under simulated gastrointestinal conditions and Caco-2 cell monolayers. These results indicate that the use of FR nanocarriers resulted in an extended-release of anthocyanins during simulated digestion. Particularly, it was observed that after a period of 2 h in the intestinal phase, the anthocyanin concentration in BAE was greater (38.01 μg/mL, P < 0.05) when FR na...
Source: Cell Research - January 1, 2024 Category: Cytology Authors: Daniela D Herrera-Balandrano Zhi Chai Li Cui Xingyu Zhao Xuan Zhao Bin Li Yiyun Yang Wuyang Huang Source Type: research
Combined histological and DNA methylome profiling approaches may provide insights into the pathophysiology of ovarian endometriomas
CONCLUSIONS: The present results support the invagination theory. Ovarian endometriomas consist of invaginated ovarian surface epithelium with celomic metaplasia and endometrium implants on the peritoneum.PMID:38107653 | PMC:PMC10721957 | DOI:10.1002/rmb2.12548 (Source: Reproductive Biology)
Source: Reproductive Biology - December 18, 2023 Category: Reproduction Medicine Authors: Ryo Maekawa Yoshiaki Ota Ikuko Ota Yumiko Mihara Hitomi Takasaki Shun Sato Isao Tamura Yuichiro Shirafuta Masahiro Shinagawa Taishi Fujimura Amon Shiroshita Toshihide Yoneda Mai Kawamoto-Jozaki Fuka Matsui Toshiaki Taketani Norihiro Sugino Source Type: research
Combined histological and DNA methylome profiling approaches may provide insights into the pathophysiology of ovarian endometriomas
CONCLUSIONS: The present results support the invagination theory. Ovarian endometriomas consist of invaginated ovarian surface epithelium with celomic metaplasia and endometrium implants on the peritoneum.PMID:38107653 | PMC:PMC10721957 | DOI:10.1002/rmb2.12548 (Source: Reproductive Biology)
Source: Reproductive Biology - December 18, 2023 Category: Reproduction Medicine Authors: Ryo Maekawa Yoshiaki Ota Ikuko Ota Yumiko Mihara Hitomi Takasaki Shun Sato Isao Tamura Yuichiro Shirafuta Masahiro Shinagawa Taishi Fujimura Amon Shiroshita Toshihide Yoneda Mai Kawamoto-Jozaki Fuka Matsui Toshiaki Taketani Norihiro Sugino Source Type: research
Using visual scores for genomic prediction of complex traits in breeding programs
In this study, we examined the main challenges of visual scores for genomic prediction and genetic parameter estimation using mixed models, Bayesian, and machine learning methods. We evaluated these approaches using simulated and real breeding data sets. Our contribution in this study is a five-fold demonstration: (i) collecting data using an intermediate number of categories (1-3 and 1-5) is the best strategy, even considering errors associated with visual scores; (ii) Linear Mixed Models and Bayesian Linear Regression are robust to the normality violation, but marginal gains can be achieved when using Bayesian Ordinal Re...
Source: TAG. Theoretical and Applied Genetics - December 15, 2023 Category: Genetics & Stem Cells Authors: Camila Ferreira Azevedo Luis Felipe Ventorim Ferr ão Juliana Benevenuto Marcos Deon Vilela de Resende Moyses Nascimento Ana Carolina Campana Nascimento Patricio R Munoz Source Type: research
Molecules, Vol. 28, Pages 8106: Effect of Gaseous Ozone and Storage Time on Polyphenolic Profile and Sugar Content in Fruits of Selected Vaccinium corymbosum L. Genotypes
r Basara
One of the best sources of antioxidant and health-promoting bioactive substances is the fruit of V. corymbosum. A potent oxidizing agent, ozone (O3), can effectively eliminate bacteria. The application of ozone gas to V. corymbosum fruit during storage had a favorable impact on the fruit&rsquo;s phenolic component and sugar content in the current investigation. After 7 days of storage, phenolic content in all highbush blueberry cultivars and clones tested increased on average by 28.60%, including anthocyanins by 34%. After 14 days of storage, an average increase of 16.50% in phenolic compounds was obse...
Source: Molecules - December 15, 2023 Category: Chemistry Authors: J ózef Gorzelany Ireneusz Kapusta Stanis ław Pluta Justyna Belcar Katarzyna Pento ś Oskar Basara Tags: Article Source Type: research
pH-responsive color-indicating film of pea protein isolate cross-linked with dialdehyde carboxylated cellulose nanofibers for pork freshness monitoring
Int J Biol Macromol. 2023 Dec 7;257(Pt 2):128671. doi: 10.1016/j.ijbiomac.2023.128671. Online ahead of print.ABSTRACTThe limited mechanical performance and responsiveness of protein-based smart packaging materials have hindered their development. To address these issues, this study prepared a pH-responsive smart film by introducing dialdehyde carboxylated cellulose nanofibers (DCCNFs) as the cross-linking agent capable of covalently reacting with proteins, and bilberry extract (BE) as a pH-responsive indicator into pea protein isolate (PPI) matrix. The results demonstrated that adding DCCNF and BE enhanced the PPI film's t...
Source: International Journal of Biological Macromolecules - December 9, 2023 Category: Biochemistry Authors: Chi Zhang Luping Qu Huan Liu Danni Cai Yi Yuan Shaoyun Wang Source Type: research
Structural homeostasis and controlled release for anthocyanin in oral film via sulfated polysaccharides complexation
Int J Biol Macromol. 2023 Nov 27:128473. doi: 10.1016/j.ijbiomac.2023.128473. Online ahead of print.ABSTRACTOral film is a novel functional carrier, which can provide a new pathway for the efficient absorption of anthocyanin. However, anthocyanin homeostasis in oral film is a prerequisite for achieving efficient absorption and utilization of anthocyanin. Herein, three sulfated polysaccharides, including chondroitin sulfate (CS), Fucoidin (FU) and λ-carrageenan (λ-CG), were complexed with blueberry anthocyanin (BA) to prepare oral film formulations using hydroxypropyl methylcellulose (HPMC) as a film-forming matrix. The a...
Source: International Journal of Biological Macromolecules - November 29, 2023 Category: Biochemistry Authors: Yiwen Bao Xi Yang Jiaxin Li Zhiying Li Zhen Cheng Mingshuang Wang Zhongxia Li Xu Si Bin Li Source Type: research
