Combined histological and DNA methylome profiling approaches may provide insights into the pathophysiology of ovarian endometriomas

CONCLUSIONS: The present results support the invagination theory. Ovarian endometriomas consist of invaginated ovarian surface epithelium with celomic metaplasia and endometrium implants on the peritoneum.PMID:38107653 | PMC:PMC10721957 | DOI:10.1002/rmb2.12548

Source: Reproductive Biology - December 18, 2023 Category: Reproduction Medicine Authors: Ryo Maekawa Yoshiaki Ota Ikuko Ota Yumiko Mihara Hitomi Takasaki Shun Sato Isao Tamura Yuichiro Shirafuta Masahiro Shinagawa Taishi Fujimura Amon Shiroshita Toshihide Yoneda Mai Kawamoto-Jozaki Fuka Matsui Toshiaki Taketani Norihiro Sugino Source Type: research