Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Comparing the Efficacy of Postoperative Antibiotic Regimens in the Treatment of Maxillofacial Fractures: A Prospective Study
CONCLUSION: A single perioperative dose of antibiotics is effective in minimizing postoperative complications following ORIF of maxillofacial fractures and there is no significant benefit in prolonging the course of antibiotics postoperatively with the need for further studies to be conducted considering comminuted, complex fractures and old fractures.CLINICAL SIGNIFICANCE: In maxillofacial trauma, fractures frequently communicate with contaminated indigenous flora on the skin surface, oral cavities, or sinus cavities. Surgery is frequently performed using an approach across a contaminated area, even in closed fractures. P...
Source: J Contemp Dent Pract - August 25, 2023 Category: Dentistry Authors: Rajat Mohanty Naman Awasthi Shrinivas Baburao Hosmani Anju Innaran Sankaranarayanan Nimish H Oberoi Praveen Kumar Singh Nikhil Singh Dharati Patel Source Type: research

Antibiotic treatment failure of uncomplicated urinary tract infections in primary care
ConclusionTreatment failure rate was lower for antibiotics with lower reported resistance rates  (AC + N). We recommend treating uncomplicated UTIs in Singapore with amoxicillin-clavulanate or nitrofurantoin, based on current local antibiograms. Diagnosis, investigations and management of UTIs remained sub-optimal. Future studies should be based on updating antibiograms, highlighting it s importance in guideline development. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - August 1, 2023 Category: Infectious Diseases Source Type: research

Phenotypic and genotypic analysis of antimicrobial resistance in Nocardia species
ConclusionsOur study provides a comprehensive understanding ofNocardia species diversity, antibiotic resistance patterns, and the molecular basis of antimicrobial resistance. Resistance appears to follow species-related patterns, suggesting a lesser role forde novo evolution or transmission of antimicrobial resistance. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - August 1, 2023 Category: Microbiology Source Type: research

Metagenomics assists in the diagnosis of a refractory, culture-negative pyoderma gangrenosum-like ulcer caused by Helicobacter cinaedi in a patient with primary agammaglobulinemia
We reported a refractory and culture-negative pyoderma gangrenosum-like ulcer caused by H. cinaedi in a patient with primary agammaglobulinemia. Metagenomic next-generation sequencing (mNGS) was applied for the identification of H. cinaedi and prolonged minocycline and amoxicillin-clavulanate potassium was used to eradicate the infection. Given the difficulties in culturing this organism, it's highly possible that H cinaedi infections have been overlooked. We suggest that early consideration of H. cinaedi infection should be suspected in immunocompromised patients presenting with unexplained skin lesions as the appropriate...
Source: Journal of Microbiology, Immunology, and Infection - July 31, 2023 Category: Microbiology Authors: Li Zhang Menglan Zhou Wei Lv Taisheng Li Yingchun Xu Zhengyin Liu Source Type: research

Metagenomics assists in the diagnosis of a refractory, culture-negative pyoderma gangrenosum-like ulcer caused by Helicobacter cinaedi in a patient with primary agammaglobulinemia
We reported a refractory and culture-negative pyoderma gangrenosum-like ulcer caused by H. cinaedi in a patient with primary agammaglobulinemia. Metagenomic next-generation sequencing (mNGS) was applied for the identification of H. cinaedi and prolonged minocycline and amoxicillin-clavulanate potassium was used to eradicate the infection. Given the difficulties in culturing this organism, it's highly possible that H cinaedi infections have been overlooked. We suggest that early consideration of H. cinaedi infection should be suspected in immunocompromised patients presenting with unexplained skin lesions as the appropriate...
Source: Journal of Microbiology, Immunology, and Infection - July 31, 2023 Category: Microbiology Authors: Li Zhang Menglan Zhou Wei Lv Taisheng Li Yingchun Xu Zhengyin Liu Source Type: research