Genetic determinants underlying the progressive phenotype of β-lactam/β-lactamase inhibitor resistance in < em > Escherichia coli < /em >
Microbiol Spectr. 2023 Oct 6:e0222123. doi: 10.1128/spectrum.02221-23. Online ahead of print.ABSTRACTCurrently, whole-genome sequencing (WGS) data have not shown strong concordance with Escherichia coli susceptibility profiles to the commonly used β-lactam/β-lactamase inhibitor (BL/BLI) combinations: ampicillin-sulbactam (SAM), amoxicillin-clavulanate (AMC), and piperacillin-tazobactam (TZP). Progressive resistance to these BL/BLIs in the absence of cephalosporin resistance, also known as extended-spectrum resistance to BL/BLI (ESRI), has been suggested to primarily result from increased copy numbers of blaTEM variants, ...
Source: Cancer Control - October 6, 2023 Category: Cancer & Oncology Authors: William C Shropshire Hatim Amiji Jordan Bremer Selvalakshmi Selvaraj Anand Benjamin Strope Pranoti Sahasrabhojane Marc Gohel Samuel Aitken Sarah Spitznogle Xiaowei Zhan Jiwoong Kim David E Greenberg Samuel A Shelburne Source Type: research
Salmonella infection among the pediatric population at a tertiary care children ’s hospital in central Nepal: a retrospective study
ConclusionSalmonella Typhi was the predominant ser. Infection was common among children between 1 and 5 years of age, showing male predominance and with the spring season contributing to a fairly higher number of cases. Antimicrobial susceptibility testing of S. Typhi showed more resistance toward nalidixic acid, with only a single isolate resistant to β-lactamase inhibitors (amoxicillin/clavulanate). Alarming multidrug resistance patterns were not observed. The MAR index in this study indicates the importance of the judicious use of antimicrobials and hospital infection prevention and control practices. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - September 29, 2023 Category: Microbiology Source Type: research
Antimicrobial therapy in the management of odontogenic infections: the penicillin-allergic patient
This retrospective analysis was performed to investigate whether clindamycin remains the preferred antibiotic for penicillin-allergic patients with odontogenic infections. The medical records of 311 patients admitted to the study department with odontogenic infections between 2018 and 2022 and treated with either intravenous amoxicillin –clavulanic acid (Augmentin) or intravenous clindamycin were analyzed. The Augmentin-treated group included 268 patients (86.2%) and the clindamycin-treated group included 43 patients (13.8%). (Source: International Journal of Oral and Maxillofacial Surgery)
Source: International Journal of Oral and Maxillofacial Surgery - September 25, 2023 Category: ENT & OMF Authors: R. Mahmoud, S. Arbel, C. Ianculovici, O. Peleg, S. Kleinman, A. Shuster Tags: Clinical Paper Source Type: research
Point prevalence probing of antimicrobial prescription patterns from a developing country
CONCLUSION: Findings demonstrate high consumption of broad-spectrum antimicrobials and emphasize the importance of expanding antimicrobial stewardship programs among hospitals. Mentoring clinical teams could help rationalize antimicrobial use.PMID:37712527 | DOI:10.1080/14787210.2023.2259098 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - September 15, 2023 Category: Infectious Diseases Authors: Nazia Khursheed Qadeer Ahsan Salima Rattani Madeeha Fatima Ali Raza Saba Tariq Tauqeer Mustafa Sadia Iqbal Sibgha Zulfiqar Syed Masroor Ahmed Ghulam Fatima Shehzad Akbar Khan Farman Ullah Rana Altaf Ahmed Saba Jamal Source Type: research
Selection for antimicrobial prophylaxis in emergency and elective transurethral procedures: Susceptibility pattern in T ürkiye
CONCLUSION: We found that currently recommended antimicrobials provide poor coverage for the most common pathogens isolated. Urologists should consider patient-based antibiotic prophylaxis in endoscopic urethral procedures, follow appropriate proto-cols, and consider local antibiotic resistance.PMID:37681729 | DOI:10.14744/tjtes.2023.99663 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - September 8, 2023 Category: Emergency Medicine Authors: Tanju Keten Melih Balci Ünsal Eroğlu Ali Yasin Özercan Şeref Coşer Serdar Ba şboğa Koray Tatl ıcı Anil Erkan Çağdaş Şenel Remzi Salar Özer Güzel Y ılmaz Aslan Altug Tuncel Ali Atan Source Type: research
Selection for antimicrobial prophylaxis in emergency and elective transurethral procedures: Susceptibility pattern in T ürkiye
CONCLUSION: We found that currently recommended antimicrobials provide poor coverage for the most common pathogens isolated. Urologists should consider patient-based antibiotic prophylaxis in endoscopic urethral procedures, follow appropriate proto-cols, and consider local antibiotic resistance.PMID:37681729 | DOI:10.14744/tjtes.2023.99663 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - September 8, 2023 Category: Emergency Medicine Authors: Tanju Keten Melih Balci Ünsal Eroğlu Ali Yasin Özercan Şeref Coşer Serdar Ba şboğa Koray Tatl ıcı Anil Erkan Çağdaş Şenel Remzi Salar Özer Güzel Y ılmaz Aslan Altug Tuncel Ali Atan Source Type: research
Selection for antimicrobial prophylaxis in emergency and elective transurethral procedures: Susceptibility pattern in T ürkiye
CONCLUSION: We found that currently recommended antimicrobials provide poor coverage for the most common pathogens isolated. Urologists should consider patient-based antibiotic prophylaxis in endoscopic urethral procedures, follow appropriate proto-cols, and consider local antibiotic resistance.PMID:37681729 | DOI:10.14744/tjtes.2023.99663 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - September 8, 2023 Category: Emergency Medicine Authors: Tanju Keten Melih Balci Ünsal Eroğlu Ali Yasin Özercan Şeref Coşer Serdar Ba şboğa Koray Tatl ıcı Anil Erkan Çağdaş Şenel Remzi Salar Özer Güzel Y ılmaz Aslan Altug Tuncel Ali Atan Source Type: research
Selection for antimicrobial prophylaxis in emergency and elective transurethral procedures: Susceptibility pattern in T ürkiye
CONCLUSION: We found that currently recommended antimicrobials provide poor coverage for the most common pathogens isolated. Urologists should consider patient-based antibiotic prophylaxis in endoscopic urethral procedures, follow appropriate proto-cols, and consider local antibiotic resistance.PMID:37681729 | DOI:10.14744/tjtes.2023.99663 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - September 8, 2023 Category: Emergency Medicine Authors: Tanju Keten Melih Balci Ünsal Eroğlu Ali Yasin Özercan Şeref Coşer Serdar Ba şboğa Koray Tatl ıcı Anil Erkan Çağdaş Şenel Remzi Salar Özer Güzel Y ılmaz Aslan Altug Tuncel Ali Atan Source Type: research
Selection for antimicrobial prophylaxis in emergency and elective transurethral procedures: Susceptibility pattern in T ürkiye
CONCLUSION: We found that currently recommended antimicrobials provide poor coverage for the most common pathogens isolated. Urologists should consider patient-based antibiotic prophylaxis in endoscopic urethral procedures, follow appropriate proto-cols, and consider local antibiotic resistance.PMID:37681729 | DOI:10.14744/tjtes.2023.99663 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - September 8, 2023 Category: Emergency Medicine Authors: Tanju Keten Melih Balci Ünsal Eroğlu Ali Yasin Özercan Şeref Coşer Serdar Ba şboğa Koray Tatl ıcı Anil Erkan Çağdaş Şenel Remzi Salar Özer Güzel Y ılmaz Aslan Altug Tuncel Ali Atan Source Type: research
Selection for antimicrobial prophylaxis in emergency and elective transurethral procedures: Susceptibility pattern in T ürkiye
CONCLUSION: We found that currently recommended antimicrobials provide poor coverage for the most common pathogens isolated. Urologists should consider patient-based antibiotic prophylaxis in endoscopic urethral procedures, follow appropriate proto-cols, and consider local antibiotic resistance.PMID:37681729 | DOI:10.14744/tjtes.2023.99663 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - September 8, 2023 Category: Emergency Medicine Authors: Tanju Keten Melih Balci Ünsal Eroğlu Ali Yasin Özercan Şeref Coşer Serdar Ba şboğa Koray Tatl ıcı Anil Erkan Çağdaş Şenel Remzi Salar Özer Güzel Y ılmaz Aslan Altug Tuncel Ali Atan Source Type: research
Selection for antimicrobial prophylaxis in emergency and elective transurethral procedures: Susceptibility pattern in T ürkiye
CONCLUSION: We found that currently recommended antimicrobials provide poor coverage for the most common pathogens isolated. Urologists should consider patient-based antibiotic prophylaxis in endoscopic urethral procedures, follow appropriate proto-cols, and consider local antibiotic resistance.PMID:37681729 | DOI:10.14744/tjtes.2023.99663 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - September 8, 2023 Category: Emergency Medicine Authors: Tanju Keten Melih Balci Ünsal Eroğlu Ali Yasin Özercan Şeref Coşer Serdar Ba şboğa Koray Tatl ıcı Anil Erkan Çağdaş Şenel Remzi Salar Özer Güzel Y ılmaz Aslan Altug Tuncel Ali Atan Source Type: research
