Thin Film Electrodes for Neuro Applications: Interview with Dave Rosa, CEO of NeuroOne
NeuroOne, a medtech company based in Minnesota, has developed the Evo Cortical Electrode and the sEEG electrode, both of which are thin film electrodes for neural recording and stimulation. The small profile and flexible nature of the electrodes allows for less invasive insertion, and the low resistance they offer delivers improved signal quality.
The devices can combine both diagnostic and therapeutic functions, which could potentially reduce the number of procedures a patient has to undergo, as diagnosis and treatment can occur during the same procedure.
The company has also conducted simulations of long-term neura...
Source: Medgadget - June 1, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Materials Neurology Neurosurgery epilepsy N1MTC seizures Source Type: blogs
Practicing medicine as a Deaf physician is an uphill battle [PODCAST]
“No one anticipated how the pandemic would impact their Deaf colleagues ’ work environment and career opportunities. Yet, 15% of adults report some form of hearing difficulty. This number increases dramatically with advancing age, with 50% of those aged 75 years or older experiencing hearing difficulty. The exact number of Deaf/Hard of Hearing (DHH) physicians andRead more …Practicing medicine as a Deaf physician is an uphill battle [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - May 26, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/the-podcast-by-kevinmd" rel="tag" data-wpel-link="internal" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Primary Care Source Type: blogs
Fight Aging! Newsletter, May 9th 2022
In conclusion, although several favorable effects are obtained in our heterochronic non-myeloablative transplantation model, additional optimization is needed for better rejuvenation effects.
More on GPNMB as a Target for Senolytic Therapies to Clear Senescent Cells
https://www.fightaging.org/archives/2022/05/more-on-gpnmb-as-a-target-for-senolytic-therapies-to-clear-senescent-cells/
You might recall that researchers recently demonstrated that vaccination against GPNMB is a senolytic strategy, reducing the harmful burden of senescent cells in aged tissues by directing the immune system to destroy these ...
Source: Fight Aging! - May 8, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Towards Targeted Gene Therapy for Hair Cell Regeneration in the Inner Ear
Age-related deafness is caused by some mix of loss of sensory hair cells of the inner ear, and loss of connections between those cells and the brain. A range of potential approaches to restore those cells are under development, and the work here is an example of this sort of work. Researchers have constructed an AAV viral vector that has some specificity for hair cells and nearby supporting cells, and which can be used to deliver a gene therapy payload that converts those supporting cells into new hair cells.
Cells of the cochlea, such as hair cells (HCs) and supporting cells (SCs), are essential for hearing. Whil...
Source: Fight Aging! - May 2, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, May 2nd 2022
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - May 1, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Age-Related Hearing Loss is Accompanied by Chronic Inflammation in the Inner Ear
Age-related neurodegeneration is strongly linked to chronic inflammation in brain tissue. Age-related hearing loss is a form of neurodegeneration, the loss of sensory hair cells in the inner ear, or the loss of the connections between those cells and the brain. Thus to find that markers of chronic inflammation in the inner ear correlate with progressive deafness is not too surprising. Ways to effectively reduce the chronic inflammation of aging should go a long way towards reducing the impact of aging on health. Senolytic therapies to remove senescent cells are the best of the present options, but more than this will be ne...
Source: Fight Aging! - April 28, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
ADHD: Here Are Five Steps I Use to Rein In My Focus
A lack of focus is the one common trait that all adults with ADHD seem to have, but focus isn’t as elusive as you might fear.The other day, a friend texted me out of the blue. He wanted a list of some of the things that I do to maintain focus. Initially, I panicked. I’ve been chronically ill since getting COVID–19 last October. I haven’t blogged in four months, so my ADHD advice muscles were all out of shape. Fortunately for my friend, I haven’t met a topic yet that I didn’t have an opinion on, so I worked up my courage and sent a list to him.Finding focus is a complicated issue foradult...
Source: The Splintered Mind by Douglas Cootey - April 23, 2022 Category: Psychiatry Tags: ADHD Goodreads Source Type: blogs
Inflation Another Reason to Rethink Buy American Protectionism
Colin GrabowGovernment data released last week placed inflation at8.5 percent over the previous 12 months —the largest such increase since December 1981—withfresh reports noting particularly pronounced price hikes for building materials and supplies. Oddly, the Biden administration decided this was an opportune time to double down on its support for protectionist “Buy American” policies that limit the federal government’s ability to purchase cheaper imported goods when spending taxpayer dollars—and thusraise prices.During a speech last Thursday President Biden highlighted his administration ’s efforts to...
Source: Cato-at-liberty - April 20, 2022 Category: American Health Authors: Colin Grabow Source Type: blogs
Fight Aging! Newsletter, March 28th 2022
In conclusion, we summarized here evidence for a novel therapeutic approach to exploit the incredible ability of mitochondria to engage multifaceted neuroprotective stress response triggered by partial complex I inhibition. This approach promises relief for multiple human conditions, and to promote healthy aging to delay the onset of neurogenerative diseases, AD in particular, where age is the greatest risk factor. There is a mounting body of evidence generated in model organisms and humans in support of the safety of chronic application of complex I inhibitors. However, a better understanding of the molecular mechanisms i...
Source: Fight Aging! - March 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Acoustic Fabric Listens to Heart and Breathing, Works as Hearing Aid
Researchers at MIT have created an “acoustic fabric” that can listen to its surroundings and convert the vibrations made by sound into electrical signals, much like the human ear or a microphone. The technology consists of piezoelectric fibers that are woven into the fabric, and the resulting machine-washable material could prove useful for a variety of medtech applications, including functioning as a heart monitor, breathing monitor, and even as a component in technology designed to help the hearing impaired.
An increasing body of research involves adding new and sometimes unexpected functionalities to the everyday...
Source: Medgadget - March 25, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Cardiology Diagnostics Materials mit Source Type: blogs
Common Contributing Causes to Age-Related Hearing Loss and Alzheimer's Disease
Age-related diseases arise from common causes, but aging is a multifaceted process of numerous interacting forms of damage and disarray, and it is usually challenging to assign a weight to any given part of aging in the causation of any given age-related disease. Still, a great deal of theorizing takes place. Here, researchers discuss the causes of hearing loss and Alzheimer's disease, given that the two conditions tend to co-occur more often than mere chance would lead to. Some underlying process contributes meaningfully to both, and in the treatment of aging, it is best to aim as close to the root causes as possible. Tha...
Source: Fight Aging! - March 23, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The New Deal and Recovery, Part 16: The Keynesian Myth, Continued
George Selgin(The first installment of " The Keynesian Myth " ishere.)All-American Money MakersAlthough conventional wisdom has it that Keynes considered government spending far more capable of ending the depression than monetary expansion, that certainly wasn ' t his view in 1931: during lectures he gave then at the University of Chicago, he disappointed faculty members who themselves favored more spending on public works over monetary easing by expressing the opposite opinion.Nor had Keynes lost faith in monetary policy in March 1933, when he published a series of articles in the LondonTimes,later republished as a pamphl...
Source: Cato-at-liberty - March 18, 2022 Category: American Health Authors: George Selgin Source Type: blogs
175 Kindness Quotes to Help You Live a Happier and Kinder Life
A simple but often underappreciated way to live a happier life is through kindness.
So in this post I’d like to share the most powerful and best kindness quotes I’ve found in the past 10+ years. Thoughts from the past 2500 years about kindness and care for others but also towards yourself.
But first, why is kindness so powerful?
Well, here’s three of my favorite reasons that I keep in mind and that helps me to try to be a kinder person:
1. I get what I give.
Most people will over time tend to treat you as you treat them.
There will of course always be exceptions but don’t let those few people stop you from focusin...
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - February 25, 2022 Category: Consumer Health News Authors: Henrik Edberg Tags: Inspirational Quotes Personal Development Source Type: blogs
Randolph Hospital (the old/bankrupt Randolph) vs. Cone Healthcare: " Self-dealing " And Unethical Business Practices. DUH. It's Not Like I Did Not Tell You So.
Before we even get started (and for the record), I was born at Cone Hospital. For years, I admired it from afar.But that was before . . .Once upon a time, twenty-four years ago this month, the executives running my hometown hospital (Randolph Hospital in Asheboro, North Carolina), fired me ( " without cause " ) . . . two weeks after I answered a terrified LDRP charge nurse ' s call in the middle of the night - to intervene in a neonatal case where the managing Family Practitioner was so " lost " that the nurse feared the baby would die before I could get there. The FP (who later styled himself to the baby ...
Source: Dr.J's HouseCalls - February 24, 2022 Category: American Health Tags: Asheboro Atrium Health Bankruptcy Bob Morrison Cone Healthcare Ed Cone Medical Whistle-blower National Health Service Corps NC Rural Heatlh Patient Safety Quality Assruance Steve Eblin Source Type: blogs
Tickboxes and tokenism?: service user involvement report 2022
This report is the result of a survey which explored people ’s experiences of service user involvement. This user-led research shows the current picture of involvement and explores the barriers that deaf and Disabled people face when wanting to share their lived experience. The report contains recommendations for those who want to run inclusive, meaningful involvement to shape their services and make them better for everyone.ReportShaping Our Lives - publications (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - February 23, 2022 Category: UK Health Authors: The King ' s Fund Library Tags: Patient involvement, experience and feedback Source Type: blogs
