Long-term performance of show-jumping horses and relationship with severity of ataxia and complications associated with myeloencephalopathy caused by equine herpes virus-1
CONCLUSIONS AND CLINICAL IMPORTANCE: Horses affected by EHM were able to return to their previous performance levels, but certain clinical variables were negatively associated with postoutbreak performance. Ataxia grade upon admission and the development of systemic signs of vasculitis and urinary complications were potential poor prognostic indicators in sport horses. Variables linked to fatality included prior vaccination against EHV-1, ataxia grade upon admission, and the development of urinary complications.PMID:38609161 | DOI:10.1111/jvim.17070 (Source: Herpes)
Source: Herpes - April 12, 2024 Category: Infectious Diseases Authors: Mar ía de la Cuesta-Torrado Ana Velloso Alvarez Patricia Neira-Egea Juan Cuervo-Arango Source Type: research
Spinocerebellar ataxia 27B (SCA27B), a frequent late-onset cerebellar ataxia
Rev Neurol (Paris). 2024 Apr 11:S0035-3787(24)00486-7. doi: 10.1016/j.neurol.2024.03.007. Online ahead of print.ABSTRACTGenetic cerebellar ataxias are still a diagnostic challenge, and yet not all of them have been identified. Very recently, in early 2023, a new cause of late-onset cerebellar ataxia (LOCA) was identified, spinocerebellar ataxia 27B (SCA27B). This is an autosomal dominant ataxia due to a GAA expansion in intron 1 of the FGF14 gene. Thanks to the many studies carried out since its discovery, it is now possible to define the clinical phenotype, its particularities, and the progression of SCA27B. It has also b...
Source: Revue Neurologique - April 12, 2024 Category: Neurology Authors: G Cl ément S Puisieux D Pellerin B Brais C Bonnet M Renaud Source Type: research
Clinical characteristics of BRAT1-related disease: a systematic literature review
ConclusionsThis is the first comprehensive systematic review to present quantitative data about clinical characteristics of BRAT1-related disease, which helps doctors to recognize and diagnose it easier. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - April 12, 2024 Category: Neurology Source Type: research
Spinocerebellar ataxia subtype 40: Report of a case and review of literature
Spinocerebellar ataxias (SCA) are a group of neurodegenerative disorders and are clinically and genetically heterogeneous. Based on the genetic variation, SCAs are grouped into three main categories: i. SCAs caused by expansion of trinucleotides (CAG/polyQ) repeats in the coding region of genes, ii. SCAs caused by repetitive amplification of non-coding regions, and ii. SCAs caused by conventional sequence variants [1]. SCA40 (OMIM # 616053), which is one of the recently described types of autosomal dominant (AD) SCA, belongs to the third category and is caused by heterozygous pathogenic variants in the CCDC88C gene (OMIM *...
Source: Parkinsonism and Related Disorders - April 11, 2024 Category: Neurology Authors: Gautam Kale, Prajnya Rangnathan, Pradeep Divate, M.K. Murthy Jagarlapudi Tags: Correspondence Source Type: research
A 52-Year-Old Woman With Dysarthria, Ataxia, Xanthelasmas, and Miliary Pulmonary Nodules
Chest. 2024 Apr;165(4):e95-e100. doi: 10.1016/j.chest.2023.10.034.ABSTRACTA 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Athena Huynh Collin Pryma Heather McPhaden Karl-Christopher Yared Yilin Zhang Katie Beadon Tony Ng Luke Y C Chen Source Type: research
A 52-Year-Old Woman With Dysarthria, Ataxia, Xanthelasmas, and Miliary Pulmonary Nodules
Chest. 2024 Apr;165(4):e95-e100. doi: 10.1016/j.chest.2023.10.034.ABSTRACTA 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Athena Huynh Collin Pryma Heather McPhaden Karl-Christopher Yared Yilin Zhang Katie Beadon Tony Ng Luke Y C Chen Source Type: research
A 52-Year-Old Woman With Dysarthria, Ataxia, Xanthelasmas, and Miliary Pulmonary Nodules
Chest. 2024 Apr;165(4):e95-e100. doi: 10.1016/j.chest.2023.10.034.ABSTRACTA 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Athena Huynh Collin Pryma Heather McPhaden Karl-Christopher Yared Yilin Zhang Katie Beadon Tony Ng Luke Y C Chen Source Type: research
A 52-Year-Old Woman With Dysarthria, Ataxia, Xanthelasmas, and Miliary Pulmonary Nodules
Chest. 2024 Apr;165(4):e95-e100. doi: 10.1016/j.chest.2023.10.034.ABSTRACTA 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Athena Huynh Collin Pryma Heather McPhaden Karl-Christopher Yared Yilin Zhang Katie Beadon Tony Ng Luke Y C Chen Source Type: research
A 52-Year-Old Woman With Dysarthria, Ataxia, Xanthelasmas, and Miliary Pulmonary Nodules
Chest. 2024 Apr;165(4):e95-e100. doi: 10.1016/j.chest.2023.10.034.ABSTRACTA 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Athena Huynh Collin Pryma Heather McPhaden Karl-Christopher Yared Yilin Zhang Katie Beadon Tony Ng Luke Y C Chen Source Type: research
A 52-Year-Old Woman With Dysarthria, Ataxia, Xanthelasmas, and Miliary Pulmonary Nodules
Chest. 2024 Apr;165(4):e95-e100. doi: 10.1016/j.chest.2023.10.034.ABSTRACTA 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Athena Huynh Collin Pryma Heather McPhaden Karl-Christopher Yared Yilin Zhang Katie Beadon Tony Ng Luke Y C Chen Source Type: research
A 52-Year-Old Woman With Dysarthria, Ataxia, Xanthelasmas, and Miliary Pulmonary Nodules
Chest. 2024 Apr;165(4):e95-e100. doi: 10.1016/j.chest.2023.10.034.ABSTRACTA 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Athena Huynh Collin Pryma Heather McPhaden Karl-Christopher Yared Yilin Zhang Katie Beadon Tony Ng Luke Y C Chen Source Type: research
A 52-Year-Old Woman With Dysarthria, Ataxia, Xanthelasmas, and Miliary Pulmonary Nodules
Chest. 2024 Apr;165(4):e95-e100. doi: 10.1016/j.chest.2023.10.034.ABSTRACTA 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Athena Huynh Collin Pryma Heather McPhaden Karl-Christopher Yared Yilin Zhang Katie Beadon Tony Ng Luke Y C Chen Source Type: research
A 52-Year-Old Woman With Dysarthria, Ataxia, Xanthelasmas, and Miliary Pulmonary Nodules
Chest. 2024 Apr;165(4):e95-e100. doi: 10.1016/j.chest.2023.10.034.ABSTRACTA 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Athena Huynh Collin Pryma Heather McPhaden Karl-Christopher Yared Yilin Zhang Katie Beadon Tony Ng Luke Y C Chen Source Type: research
A 52-Year-Old Woman With Dysarthria, Ataxia, Xanthelasmas, and Miliary Pulmonary Nodules
Chest. 2024 Apr;165(4):e95-e100. doi: 10.1016/j.chest.2023.10.034.ABSTRACTA 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years...
Source: Chest - April 10, 2024 Category: Respiratory Medicine Authors: Athena Huynh Collin Pryma Heather McPhaden Karl-Christopher Yared Yilin Zhang Katie Beadon Tony Ng Luke Y C Chen Source Type: research
