Optimizing Communication in Ataxia: A Multifaceted Approach to Alternative and Augmentative Communication (AAC)
Cerebellum. 2024 Mar 7. doi: 10.1007/s12311-024-01675-0. Online ahead of print.ABSTRACTThe progression of multisystem neurodegenerative diseases such as ataxia significantly impacts speech and communication, necessitating adaptive clinical care strategies. With the deterioration of speech, Alternative and Augmentative Communication (AAC) can play an ever increasing role in daily life for individuals with ataxia. This review describes the spectrum of AAC resources available, ranging from unaided gestures and sign language to high-tech solutions like speech-generating devices (SGDs) and eye-tracking technology. Despite the a...
Source: Cerebellum - March 6, 2024 Category: Neuroscience Authors: Adam P Vogel Caroline Spencer Katie Burke Daniella de Bruyn Peter Gibilisco Scott Blackman Jennifer M Vojtech Thayabaran Kathiresan Source Type: research
Correction: Cerebellar Volumetry in Ataxias: Relation to Ataxia Severity and Duration
Cerebellum. 2024 Mar 6. doi: 10.1007/s12311-024-01681-2. Online ahead of print.NO ABSTRACTPMID:38446346 | DOI:10.1007/s12311-024-01681-2 (Source: Cerebellum)
Source: Cerebellum - March 6, 2024 Category: Neuroscience Authors: M ónica Ferreira Tamara Schaprian David K ügler Martin Reuter Katharina Deike-Hoffmann Dagmar Timmann Thomas M Ernst Paola Giunti Hector Garcia-Moreno Bart van de Warrenburg Judith van Gaalen Jeroen de Vries Heike Jacobi Katharina Marie Steiner G ülin Source Type: research
Optimizing Communication in Ataxia: A Multifaceted Approach to Alternative and Augmentative Communication (AAC)
Cerebellum. 2024 Mar 7. doi: 10.1007/s12311-024-01675-0. Online ahead of print.ABSTRACTThe progression of multisystem neurodegenerative diseases such as ataxia significantly impacts speech and communication, necessitating adaptive clinical care strategies. With the deterioration of speech, Alternative and Augmentative Communication (AAC) can play an ever increasing role in daily life for individuals with ataxia. This review describes the spectrum of AAC resources available, ranging from unaided gestures and sign language to high-tech solutions like speech-generating devices (SGDs) and eye-tracking technology. Despite the a...
Source: Cerebellum - March 6, 2024 Category: Neuroscience Authors: Adam P Vogel Caroline Spencer Katie Burke Daniella de Bruyn Peter Gibilisco Scott Blackman Jennifer M Vojtech Thayabaran Kathiresan Source Type: research
Correction: Cerebellar Volumetry in Ataxias: Relation to Ataxia Severity and Duration
(Source: The Cerebellum)
Source: The Cerebellum - March 6, 2024 Category: Neurology Source Type: research
Spermidine treatment: induction of autophagy but also apoptosis?
Machado-Joseph disease (MJD), also known as spinocerebellar ataxia type 3, is a fatal neurodegenerative disease that causes loss of balance and motor co-ordination, eventually leading to paralysis. It is cause... (Source: Molecular Brain)
Source: Molecular Brain - March 5, 2024 Category: Neuroscience Authors: Maxinne Watchon, Amanda L. Wright, Holly I. Ahel, Katherine J. Robinson, Stuart K. Plenderleith, Andrea Kuriakose, Kristy C. Yuan and Angela S. Laird Tags: Research Source Type: research
Suspected malnutrition-induced reversible feline skin fragility syndrome in a cat with congenital axial deformities
Can Vet J. 2024 Mar;65(3):227-233.ABSTRACTA stray cat, an intact female Japanese domestic shorthair cat of unknown age (suspected to be a young adult), was rescued. The cat was lethargic and thin and had marked skin fragility, delayed wound healing without skin hyperextensibility, and hind limb proprioceptive ataxia and paresis. Survey radiography, computed tomography, and magnetic resonance imaging revealed congenital vertebral anomalies, including thoracolumbar transitional vertebrae, scoliosis resulting from a thoracic lateral wedge-shaped vertebra, and a kinked tail, and a dilated spinal cord central canal. Through nut...
Source: The Canadian Veterinary Journal - March 4, 2024 Category: Veterinary Research Authors: Yoshihiko Yu Tadashi Miyamoto Yui Kimura Kazuhito Itamoto Masaki Michishita Hitoshi Hatakeyama Tomokazu Nagashima Rikako Asada Tomomi Yamaguchi Daisuke Hasegawa Yoshihiro Nomura Leslie A Lyons Tomoki Kosho Source Type: research
Suspected malnutrition-induced reversible feline skin fragility syndrome in a cat with congenital axial deformities
Can Vet J. 2024 Mar;65(3):227-233.ABSTRACTA stray cat, an intact female Japanese domestic shorthair cat of unknown age (suspected to be a young adult), was rescued. The cat was lethargic and thin and had marked skin fragility, delayed wound healing without skin hyperextensibility, and hind limb proprioceptive ataxia and paresis. Survey radiography, computed tomography, and magnetic resonance imaging revealed congenital vertebral anomalies, including thoracolumbar transitional vertebrae, scoliosis resulting from a thoracic lateral wedge-shaped vertebra, and a kinked tail, and a dilated spinal cord central canal. Through nut...
Source: The Canadian Veterinary Journal - March 4, 2024 Category: Veterinary Research Authors: Yoshihiko Yu Tadashi Miyamoto Yui Kimura Kazuhito Itamoto Masaki Michishita Hitoshi Hatakeyama Tomokazu Nagashima Rikako Asada Tomomi Yamaguchi Daisuke Hasegawa Yoshihiro Nomura Leslie A Lyons Tomoki Kosho Source Type: research
Structural Brain Correlates of Sleep Microstructure in Spinocerebellar Ataxia Type 2 and its Role on Clinical Phenotype
The objective of the study is to explore the relationship between sleep microstructure and brain atrophy in SCA2 and its role in the clinical phenotype. Fourteen SCA2 mutation carriers (7 pre-manifest and 7 manifest subjects) underwent polysomnographic, structural MRI, and clinical assessments. Particularly, markers of REM and non-REM sleep microstructure, measures of cerebellar and brainstem atrophy, and clinical scores were analyzed through correlation and mediation analyses. The sleep spindle activity exhibited a negative correlation with the number of trials required to complete the verbal memory test (VMT), and a posi...
Source: Cerebellum - March 4, 2024 Category: Neuroscience Authors: Roberto Rodr íguez-Labrada Nalia Canales-Ochoa Maria de Lourdes Galicia-Polo Edilia Cruz-Rivas Sandro Romanzetti Arnoy Pe ña-Acosta Anneli é Estupiñán-Rodríguez Yaime é Vázquez-Mojena Imis Dogan Georg Auburger Kathrin Reetz Luis Vel ázquez-Pérez Source Type: research
Suspected malnutrition-induced reversible feline skin fragility syndrome in a cat with congenital axial deformities
Can Vet J. 2024 Mar;65(3):227-233.ABSTRACTA stray cat, an intact female Japanese domestic shorthair cat of unknown age (suspected to be a young adult), was rescued. The cat was lethargic and thin and had marked skin fragility, delayed wound healing without skin hyperextensibility, and hind limb proprioceptive ataxia and paresis. Survey radiography, computed tomography, and magnetic resonance imaging revealed congenital vertebral anomalies, including thoracolumbar transitional vertebrae, scoliosis resulting from a thoracic lateral wedge-shaped vertebra, and a kinked tail, and a dilated spinal cord central canal. Through nut...
Source: The Canadian Veterinary Journal - March 4, 2024 Category: Veterinary Research Authors: Yoshihiko Yu Tadashi Miyamoto Yui Kimura Kazuhito Itamoto Masaki Michishita Hitoshi Hatakeyama Tomokazu Nagashima Rikako Asada Tomomi Yamaguchi Daisuke Hasegawa Yoshihiro Nomura Leslie A Lyons Tomoki Kosho Source Type: research
Structural Brain Correlates of Sleep Microstructure in Spinocerebellar Ataxia Type 2 and its Role on Clinical Phenotype
The objective of the study is to explore the relationship between sleep microstructure and brain atrophy in SCA2 and its role in the clinical phenotype. Fourteen SCA2 mutation carriers (7 pre-manifest and 7 manifest subjects) underwent polysomnographic, structural MRI, and clinical assessments. Particularly, markers of REM and non-REM sleep microstructure, measures of cerebellar and brainstem atrophy, and clinical scores were analyzed through correlation and mediation analyses. The sleep spindle activity exhibited a negative correlation with the number of trials required to complete the verbal memory test (VMT), and a posi...
Source: Cerebellum - March 4, 2024 Category: Neuroscience Authors: Roberto Rodr íguez-Labrada Nalia Canales-Ochoa Maria de Lourdes Galicia-Polo Edilia Cruz-Rivas Sandro Romanzetti Arnoy Pe ña-Acosta Anneli é Estupiñán-Rodríguez Yaime é Vázquez-Mojena Imis Dogan Georg Auburger Kathrin Reetz Luis Vel ázquez-Pérez Source Type: research
Suspected malnutrition-induced reversible feline skin fragility syndrome in a cat with congenital axial deformities
Can Vet J. 2024 Mar;65(3):227-233.ABSTRACTA stray cat, an intact female Japanese domestic shorthair cat of unknown age (suspected to be a young adult), was rescued. The cat was lethargic and thin and had marked skin fragility, delayed wound healing without skin hyperextensibility, and hind limb proprioceptive ataxia and paresis. Survey radiography, computed tomography, and magnetic resonance imaging revealed congenital vertebral anomalies, including thoracolumbar transitional vertebrae, scoliosis resulting from a thoracic lateral wedge-shaped vertebra, and a kinked tail, and a dilated spinal cord central canal. Through nut...
Source: The Canadian Veterinary Journal - March 4, 2024 Category: Veterinary Research Authors: Yoshihiko Yu Tadashi Miyamoto Yui Kimura Kazuhito Itamoto Masaki Michishita Hitoshi Hatakeyama Tomokazu Nagashima Rikako Asada Tomomi Yamaguchi Daisuke Hasegawa Yoshihiro Nomura Leslie A Lyons Tomoki Kosho Source Type: research
Suspected malnutrition-induced reversible feline skin fragility syndrome in a cat with congenital axial deformities
Can Vet J. 2024 Mar;65(3):227-233.ABSTRACTA stray cat, an intact female Japanese domestic shorthair cat of unknown age (suspected to be a young adult), was rescued. The cat was lethargic and thin and had marked skin fragility, delayed wound healing without skin hyperextensibility, and hind limb proprioceptive ataxia and paresis. Survey radiography, computed tomography, and magnetic resonance imaging revealed congenital vertebral anomalies, including thoracolumbar transitional vertebrae, scoliosis resulting from a thoracic lateral wedge-shaped vertebra, and a kinked tail, and a dilated spinal cord central canal. Through nut...
Source: The Canadian Veterinary Journal - March 4, 2024 Category: Veterinary Research Authors: Yoshihiko Yu Tadashi Miyamoto Yui Kimura Kazuhito Itamoto Masaki Michishita Hitoshi Hatakeyama Tomokazu Nagashima Rikako Asada Tomomi Yamaguchi Daisuke Hasegawa Yoshihiro Nomura Leslie A Lyons Tomoki Kosho Source Type: research
Suspected malnutrition-induced reversible feline skin fragility syndrome in a cat with congenital axial deformities
Can Vet J. 2024 Mar;65(3):227-233.ABSTRACTA stray cat, an intact female Japanese domestic shorthair cat of unknown age (suspected to be a young adult), was rescued. The cat was lethargic and thin and had marked skin fragility, delayed wound healing without skin hyperextensibility, and hind limb proprioceptive ataxia and paresis. Survey radiography, computed tomography, and magnetic resonance imaging revealed congenital vertebral anomalies, including thoracolumbar transitional vertebrae, scoliosis resulting from a thoracic lateral wedge-shaped vertebra, and a kinked tail, and a dilated spinal cord central canal. Through nut...
Source: The Canadian Veterinary Journal - March 4, 2024 Category: Veterinary Research Authors: Yoshihiko Yu Tadashi Miyamoto Yui Kimura Kazuhito Itamoto Masaki Michishita Hitoshi Hatakeyama Tomokazu Nagashima Rikako Asada Tomomi Yamaguchi Daisuke Hasegawa Yoshihiro Nomura Leslie A Lyons Tomoki Kosho Source Type: research
Suspected malnutrition-induced reversible feline skin fragility syndrome in a cat with congenital axial deformities
Can Vet J. 2024 Mar;65(3):227-233.ABSTRACTA stray cat, an intact female Japanese domestic shorthair cat of unknown age (suspected to be a young adult), was rescued. The cat was lethargic and thin and had marked skin fragility, delayed wound healing without skin hyperextensibility, and hind limb proprioceptive ataxia and paresis. Survey radiography, computed tomography, and magnetic resonance imaging revealed congenital vertebral anomalies, including thoracolumbar transitional vertebrae, scoliosis resulting from a thoracic lateral wedge-shaped vertebra, and a kinked tail, and a dilated spinal cord central canal. Through nut...
Source: The Canadian Veterinary Journal - March 4, 2024 Category: Veterinary Research Authors: Yoshihiko Yu Tadashi Miyamoto Yui Kimura Kazuhito Itamoto Masaki Michishita Hitoshi Hatakeyama Tomokazu Nagashima Rikako Asada Tomomi Yamaguchi Daisuke Hasegawa Yoshihiro Nomura Leslie A Lyons Tomoki Kosho Source Type: research
Suspected malnutrition-induced reversible feline skin fragility syndrome in a cat with congenital axial deformities
Can Vet J. 2024 Mar;65(3):227-233.ABSTRACTA stray cat, an intact female Japanese domestic shorthair cat of unknown age (suspected to be a young adult), was rescued. The cat was lethargic and thin and had marked skin fragility, delayed wound healing without skin hyperextensibility, and hind limb proprioceptive ataxia and paresis. Survey radiography, computed tomography, and magnetic resonance imaging revealed congenital vertebral anomalies, including thoracolumbar transitional vertebrae, scoliosis resulting from a thoracic lateral wedge-shaped vertebra, and a kinked tail, and a dilated spinal cord central canal. Through nut...
Source: The Canadian Veterinary Journal - March 4, 2024 Category: Veterinary Research Authors: Yoshihiko Yu Tadashi Miyamoto Yui Kimura Kazuhito Itamoto Masaki Michishita Hitoshi Hatakeyama Tomokazu Nagashima Rikako Asada Tomomi Yamaguchi Daisuke Hasegawa Yoshihiro Nomura Leslie A Lyons Tomoki Kosho Source Type: research
