Pharmacological and immunomodulatory modes of action of medically important phytochemicals against arthritis: A molecular insight
Mol Biol Rep. 2024 Mar 27;51(1):448. doi: 10.1007/s11033-024-09386-9.ABSTRACTArthritis is a common illness that affects joints and it may result in inflammation and pain. Even though arthritis usually affects older people, it can also affect children, adults, and both genders. Numerous arthritic mouse models have been developed but the CIA model of rheumatoid arthritis (RA) has received the most attention. With the use of steroids, DMARDs, and NSAIDs, therapy objectives such as reduced disease incidence and better pain management are achieved. Long-term usage of these therapeutic approaches may have negative side effects. ...
Source: Molecular Biology Reports - March 27, 2024 Category: Molecular Biology Authors: None Aqsa Shaukat Ali Muhammad Summer Saima Yousaf Laiba Nazakat Shehzeen Noor Source Type: research
Dietary Supplement-Induced Hepatotoxicity: A Clinical Perspective
This article delves into the clinical perspective of DS-related hepatotoxicity, highlighting key concepts such as a systematic diagnostic approach. The discussion extends to notable examples of both currently popular and potential future dietary supplements, such as garcinia cambogia, turmeric, and ashwagandha, accompanied by an overview of recent findings. Causality assessment tools play a crucial role in establishing a connection between these products and instances of liver injury, with consideration of the advantages and disadvantages associated with their use. Fostering a comprehensive understanding of regulatory stan...
Source: Journal of Dietary Supplements - March 26, 2024 Category: Nutrition Authors: Jordan Carty Victor J Navarro Source Type: research
