Withania somnifera and Trigonella foenum-graecum as ingredients of testosterone-boosting supplements: Possible clinical implications
Adv Clin Exp Med. 2024 Apr 17. doi: 10.17219/acem/185743. Online ahead of print.ABSTRACTThis narrative review provides an overview of scientific studies on dietary supplements that may affect circulating testosterone (T) levels to explore which substances are scientifically proven to increase T concentration. We also review the scientific literature for their potential mechanisms and laboratory test changes triggered by their use. Based on the analysis of existing data on substances used to increase endogenous T levels, especially double-blind placebo-controlled randomized clinical trials, we selected 2 herbal extracts wit...
Source: Adv Data - April 17, 2024 Category: Epidemiology Authors: Monika Skrzypiec-Spring Andrzej Pokrywka Justyna Kuliczkowska-P łaksej Adam Szel ąg Marek Bolanowski Source Type: research
Withania somnifera and Trigonella foenum-graecum as ingredients of testosterone-boosting supplements: Possible clinical implications
Adv Clin Exp Med. 2024 Apr 17. doi: 10.17219/acem/185743. Online ahead of print.ABSTRACTThis narrative review provides an overview of scientific studies on dietary supplements that may affect circulating testosterone (T) levels to explore which substances are scientifically proven to increase T concentration. We also review the scientific literature for their potential mechanisms and laboratory test changes triggered by their use. Based on the analysis of existing data on substances used to increase endogenous T levels, especially double-blind placebo-controlled randomized clinical trials, we selected 2 herbal extracts wit...
Source: Adv Data - April 17, 2024 Category: Epidemiology Authors: Monika Skrzypiec-Spring Andrzej Pokrywka Justyna Kuliczkowska-P łaksej Adam Szel ąg Marek Bolanowski Source Type: research
Neuroprotective effect of Withania somnifera leaves extract nanoemulsion against penconazole-induced neurotoxicity in albino rats via modulating TGF- β1/Smad2 signaling pathway
In conclusion, WSLE NE markedly enhanced the permeability of plant extract constituents through the blood brain barrier to boost its neuroprotective effect against PEN-induced neurotoxicity. (Source: Inflammopharmacology)
Source: Inflammopharmacology - April 17, 2024 Category: Drugs & Pharmacology Source Type: research
Comprehensive Insights into Pathophysiology of Alzheimer's Disease: Herbal Approaches for Mitigating Neurodegeneration
In conclusion, a comprehensive understanding of the complex pathophysiology of AD and the exploration of herbal interventions offer a holistic approach to managing this devastating disease. Future research should address the limitations associated with herbal drugs and further evaluate the efficacy of promising natural products in clinical settings.PMID:38623983 | DOI:10.2174/0115672050309057240404075003 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - April 16, 2024 Category: Neurology Authors: Debasis Sen Sunny Rathee Vishal Pandey Sanjay K Jain Umesh K Patil Source Type: research
Comprehensive Insights into Pathophysiology of Alzheimer's Disease: Herbal Approaches for Mitigating Neurodegeneration
In conclusion, a comprehensive understanding of the complex pathophysiology of AD and the exploration of herbal interventions offer a holistic approach to managing this devastating disease. Future research should address the limitations associated with herbal drugs and further evaluate the efficacy of promising natural products in clinical settings.PMID:38623983 | DOI:10.2174/0115672050309057240404075003 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - April 16, 2024 Category: Neurology Authors: Debasis Sen Sunny Rathee Vishal Pandey Sanjay K Jain Umesh K Patil Source Type: research
The Potential Pharmacological Effects of Natural Product
Withaferin A in Cancer: Opportunities and Challenges for Clinical
Translation
Planta Med DOI: 10.1055/a-2289-9600Cancer is one of the biggest health concerns with a complex pathophysiology.
Currently, available chemotherapeutic drugs are showing deleterious side
effects, and tumors often show resistance to treatment. Hence, extensive
research is required to develop new treatment strategies to fight against
cancer. Natural resources from plants are at the forefront of hunting novel
drugs to treat various types of cancers. Withaferin A (WA) is a naturally
occurring withanolide, a biologically active component obtained from the plant
...
Source: Planta Medica - April 8, 2024 Category: Drugs & Pharmacology Authors: Devabattula, Geetanjali Panda, Biswajit Yadav, Rachana Godugu, Chandraiah Tags: Reviews Source Type: research
In Vitro and In Vivo Anti-Inflammatory Activity of a Combination of Extracts from Cinnamomum zeylanicum, Alpinia galanga, and Withania somnifera used in Unani Medicine
CONCLUSION: It may be inferred that the ethanolic extract of the three herbs has strong anti-inflammatory activity in the tested inflammatory models and the extract is safe as it did not show any cytotoxic effects in both in vitro and in vivo conditions.PMID:38581340 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Mohamed Shiffa Munawwar Husain Kazmi Syed Mansoor Ali Aleena Anwar Mohammed Yasir Nazeem Fahamiya Mohammad Mahfuzul Haque Source Type: research
In Vitro and In Vivo Anti-Inflammatory Activity of a Combination of Extracts from Cinnamomum zeylanicum, Alpinia galanga, and Withania somnifera used in Unani Medicine
CONCLUSION: It may be inferred that the ethanolic extract of the three herbs has strong anti-inflammatory activity in the tested inflammatory models and the extract is safe as it did not show any cytotoxic effects in both in vitro and in vivo conditions.PMID:38581340 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Mohamed Shiffa Munawwar Husain Kazmi Syed Mansoor Ali Aleena Anwar Mohammed Yasir Nazeem Fahamiya Mohammad Mahfuzul Haque Source Type: research
In Vitro and In Vivo Anti-Inflammatory Activity of a Combination of Extracts from Cinnamomum zeylanicum, Alpinia galanga, and Withania somnifera used in Unani Medicine
CONCLUSION: It may be inferred that the ethanolic extract of the three herbs has strong anti-inflammatory activity in the tested inflammatory models and the extract is safe as it did not show any cytotoxic effects in both in vitro and in vivo conditions.PMID:38581340 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Mohamed Shiffa Munawwar Husain Kazmi Syed Mansoor Ali Aleena Anwar Mohammed Yasir Nazeem Fahamiya Mohammad Mahfuzul Haque Source Type: research
In Vitro and In Vivo Anti-Inflammatory Activity of a Combination of Extracts from Cinnamomum zeylanicum, Alpinia galanga, and Withania somnifera used in Unani Medicine
CONCLUSION: It may be inferred that the ethanolic extract of the three herbs has strong anti-inflammatory activity in the tested inflammatory models and the extract is safe as it did not show any cytotoxic effects in both in vitro and in vivo conditions.PMID:38581340 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Mohamed Shiffa Munawwar Husain Kazmi Syed Mansoor Ali Aleena Anwar Mohammed Yasir Nazeem Fahamiya Mohammad Mahfuzul Haque Source Type: research
In Vitro and In Vivo Anti-Inflammatory Activity of a Combination of Extracts from Cinnamomum zeylanicum, Alpinia galanga, and Withania somnifera used in Unani Medicine
CONCLUSION: It may be inferred that the ethanolic extract of the three herbs has strong anti-inflammatory activity in the tested inflammatory models and the extract is safe as it did not show any cytotoxic effects in both in vitro and in vivo conditions.PMID:38581340 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Mohamed Shiffa Munawwar Husain Kazmi Syed Mansoor Ali Aleena Anwar Mohammed Yasir Nazeem Fahamiya Mohammad Mahfuzul Haque Source Type: research
In Vitro and In Vivo Anti-Inflammatory Activity of a Combination of Extracts from Cinnamomum zeylanicum, Alpinia galanga, and Withania somnifera used in Unani Medicine
CONCLUSION: It may be inferred that the ethanolic extract of the three herbs has strong anti-inflammatory activity in the tested inflammatory models and the extract is safe as it did not show any cytotoxic effects in both in vitro and in vivo conditions.PMID:38581340 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Mohamed Shiffa Munawwar Husain Kazmi Syed Mansoor Ali Aleena Anwar Mohammed Yasir Nazeem Fahamiya Mohammad Mahfuzul Haque Source Type: research
Ashwagandha
J Prim Health Care. 2024 Mar;16(1):112-114. doi: 10.1071/HC23172.NO ABSTRACTPMID:38546784 | DOI:10.1071/HC23172 (Source: Journal of Primary Health Care)
Source: Journal of Primary Health Care - March 28, 2024 Category: Primary Care Authors: Xin Yi Lim Joanne Barnes Source Type: research
Ashwagandha
J Prim Health Care. 2024 Mar;16(1):112-114. doi: 10.1071/HC23172.NO ABSTRACTPMID:38546784 | DOI:10.1071/HC23172 (Source: Primary Care)
Source: Primary Care - March 28, 2024 Category: Primary Care Authors: Xin Yi Lim Joanne Barnes Source Type: research
Ashwagandha
J Prim Health Care. 2024 Mar;16(1):112-114. doi: 10.1071/HC23172.NO ABSTRACTPMID:38546784 | DOI:10.1071/HC23172 (Source: Journal of Primary Health Care)
Source: Journal of Primary Health Care - March 28, 2024 Category: Primary Care Authors: Xin Yi Lim Joanne Barnes Source Type: research
