Acute myopericarditis in a patient with ulcerative colitis and the role of mesalamine: a case report
No abstract available (Source: Gastroenterology Nursing)
Source: Gastroenterology Nursing - July 1, 2022 Category: Nursing Tags: Departments Source Type: research
Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease
Gut Liver. 2022 Jun 7. doi: 10.5009/gnl210479. Online ahead of print.ABSTRACTThe association between inflammatory bowel disease and colorectal cancer is well known. Although the overall incidence of inflammatory bowel disease has declined recently, patients with this disease still have a 1.7-fold increased risk of colorectal cancer. The risk factors for developing colorectal cancer include extensive colitis, young age at diagnosis, disease duration, primary sclerosing cholangitis, chronic colonic mucosal inflammation, dysplasia lesion, and post-inflammatory polyps. In patients with inflammatory bowel disease, control of ch...
Source: Gut and Liver - June 7, 2022 Category: Gastroenterology Authors: Shun-Wen Hsiao Hsu-Heng Yen Yang-Yuan Chen Source Type: research
Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease
Gut Liver. 2022 Jun 7. doi: 10.5009/gnl210479. Online ahead of print.ABSTRACTThe association between inflammatory bowel disease and colorectal cancer is well known. Although the overall incidence of inflammatory bowel disease has declined recently, patients with this disease still have a 1.7-fold increased risk of colorectal cancer. The risk factors for developing colorectal cancer include extensive colitis, young age at diagnosis, disease duration, primary sclerosing cholangitis, chronic colonic mucosal inflammation, dysplasia lesion, and post-inflammatory polyps. In patients with inflammatory bowel disease, control of ch...
Source: Cancer Control - June 7, 2022 Category: Cancer & Oncology Authors: Shun-Wen Hsiao Hsu-Heng Yen Yang-Yuan Chen Source Type: research
Shenling Baizhu Powder Alleviates TNBS-Induced Colitis in Rats by Improving Intestinal Epithelial Permeability and Inhibiting Inflammation Through the TLR5/MyD88/NF- κB Pathway
Conclusion: The results of our study suggest that SBP has therapeutic effects on TNBS-induced colitis and potential value in treating and maintaining remission of colitis. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - April 28, 2022 Category: Drugs & Pharmacology Source Type: research
Subcutaneous golimumab to treat a biological na ïve chronically active ulcerative colitis child. A case report
CONCLUSION: This case demonstrated that golimumab 200 mg, 100 mg at week 0, 2 as an induction then 50 mg every four weeks was efficacious and safe in<45 kg children, there were no side effects or adverse events during two years therapy period.PMID:35386809 | PMC:PMC8977938 | DOI:10.1016/j.amsu.2022.103456 (Source: Annals of Medicine)
Source: Annals of Medicine - April 7, 2022 Category: Internal Medicine Authors: Marouf M Alhalabi Ahmad J Abbas Source Type: research
Corticosteroids and Mesalamine Versus Corticosteroids for Acute Severe Ulcerative Colitis: A Randomized Controlled Trial
Corticosteroids are the mainstay of treatment for hospitalized patients with acute severe ulcerative colitis (ASUC). However, whether the addition/continuation of mesalamine with corticosteroids during hospitalization is superior to corticosteroids alone is unknown. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - April 1, 2022 Category: Gastroenterology Authors: Shomron Ben-Horin, Ofir Har-Noy, Konstantinos H. Katsanos, Xavier Roblin, Minhu Chen, Xiang Gao, Doron Schwartz, Jae Hee Cheon, Monica Cesarini, Daniela Bojic, Marijana Protic, Angeliki Theodoropoulou, Heba Abu-Kaf, Tal Engel, Jian Tang, Pauline Veyrard, Source Type: research
Current Guidelines and Controversies in the Management of Diverticulitis
AbstractPurpose of ReviewThis review discusses the most recent studies and guidelines regarding the treatment of acute diverticulitis. It specifically focuses on current controversies in initial evaluation, management, and follow-up after discharge.Recent FindingsMany recent large-scale randomized control studies (such as the AVOD and DIABOLO trials) and systematic reviews have changed our current understanding of diverticulitis. Specifically, this review focuses on new evidence in stratifying patients, use of antibiotics, the indications for new therapies, and recommended follow-up after an acute episode.SummaryThe most i...
Source: Current Emergency and Hospital Medicine Reports - March 31, 2022 Category: Emergency Medicine Source Type: research
Intravaginal Mesalamine Administration: A Novel Technique for Neovaginal Diversion Colitis
Background: Vaginoplasty utilizing sigmoid colon has the advantage of spontaneous mucus production similar to a native vagina and appropriate vaginal length. Neovaginal diverting colitis, a potential side effect of sigmoid vaginoplasty, is an inflammatory process that affects the colonic tissue. Patients may present with vaginal pain, postcoital bleeding, vaginal spotting, and dyspareunia. Treatment for neovaginal diversion colitis includes a combination of intravaginal application mesalamine foam and sodium butyrate enemas. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - March 18, 2022 Category: OBGYN Authors: Andrew Lupo, Ashli Lawson, Rebecca Rentea, John Rosen, Christina Low Kapalu Tags: 52. Source Type: research
5-Aminosalicylic Acid Chemoprevention in Inflammatory Bowel Diseases: Is It Necessary in the Age of Biologics and Small Molecules?
Inflamm Intest Dis. 2021 Sep 3;7(1):28-35. doi: 10.1159/000518865. eCollection 2022 Jan.ABSTRACTBACKGROUND: Due to the increased incidence of colorectal cancer in inflammatory bowel diseases (IBDs), the value of chemoprevention for this patient group has been repeatedly debated in the past decade. This review describes available evidence and the current recommendations for chemoprevention in national and international guidelines IBD guidelines.SUMMARY: 5-Aminosalicylic acid (5-ASA) compounds are the preferred therapeutic option for mild to moderate ulcerative colitis (UC). Aside from the known anti-inflammatory effects, th...
Source: Cancer Control - February 28, 2022 Category: Cancer & Oncology Authors: Hans Herfarth Stephan R Vavricka Source Type: research
Prooxidant activity of aminophenol compounds: copper-dependent generation of reactive oxygen species
Biometals. 2022 Feb 14. doi: 10.1007/s10534-022-00367-8. Online ahead of print.ABSTRACTProoxidant properties of aminophenol, the constituent of acetaminophen and mesalamine, were examined. Aminophenol compounds/copper-dependent formation of reactive oxygen species was analyzed by the inactivation of aconitase, the most sensitive enzyme to oxidative stress in permeabilized yeast cells. Aminophenol compounds of 2 (ortho)- and 4 (para)- substituents, but not 3 (meta)-isomer produced reactive oxygen species in the presence of copper (cupric) ion or iron. The inactivation required sodium azide the inhibitor of catalase, suggest...
Source: Biometals - February 14, 2022 Category: Biochemistry Authors: Keiko Murakami Masataka Yoshino Source Type: research
Prooxidant activity of aminophenol compounds: copper-dependent generation of reactive oxygen species
Biometals. 2022 Feb 14. doi: 10.1007/s10534-022-00367-8. Online ahead of print.ABSTRACTProoxidant properties of aminophenol, the constituent of acetaminophen and mesalamine, were examined. Aminophenol compounds/copper-dependent formation of reactive oxygen species was analyzed by the inactivation of aconitase, the most sensitive enzyme to oxidative stress in permeabilized yeast cells. Aminophenol compounds of 2 (ortho)- and 4 (para)- substituents, but not 3 (meta)-isomer produced reactive oxygen species in the presence of copper (cupric) ion or iron. The inactivation required sodium azide the inhibitor of catalase, suggest...
Source: Biometals - February 14, 2022 Category: Biochemistry Authors: Keiko Murakami Masataka Yoshino Source Type: research
SARS-CoV-2 (COVID-19) pneumonia patient treated with two doses of infliximab within 2 weeks for acute severe ulcerative colitis: A case report
We report the case of a 34-year-old male with 6 to 8 times bloody diarrhea, fever, and cramping abdominal pain. Ulcerative colitis was diagnosed 6 months earlier and treated with mesalamine 80 mg/kg/day and azathioprine 2.5 mg/kg/day. The patient had never undergone surgery before. Sigmoidoscopy revealed multiple ulcerations and spontaneous bleeding, and the colon samples tested negative for cytomegalovirus and Clostridium difficile. However, intravenous corticosteroids did not induce remission. A nasopharyngeal swab tested positive for SARS-CoV-2.
Diagnosis:
Acute severe ulcerative colitis and SARS-CoV-2 (COVID...
Source: Medicine - January 28, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
