MKSAP: 38-year-old man with ulcerative colitis
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 38-year-old man is evaluated in follow-up after a diagnosis of ulcerative colitis. Ten days ago he was started on prednisone, 60 mg/d, but his symptoms have not improved. He has six to nine bloody bowel movements per day and moderate abdominal pain. He has decreased his oral intake because eating exacerbates his pain and diarrhea. On physical examination, temperature is 37.0 °C (98.6 °F), blood pressure is 110/56 mm Hg, and pulse rate is 96/min. He is pale but in no distress. The abdomen is diffusely tender ...
Source: Kevin, M.D. - Medical Weblog - May 5, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Gastroenterology Source Type: blogs

MKSAP: 22-year-old woman is evaluated for a flare of Crohn disease
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 22-year-old woman is evaluated for a flare of Crohn disease. A colonoscopy performed 6 months ago showed moderate, patchy, left-sided colitis extending from the descending colon to the splenic flexure. She responded to therapy with prednisone but declined maintenance therapy in advance of conceiving. She is now 12 weeks pregnant and for the past 2 weeks has experienced bloody diarrhea and left-sided abdominal pain. On physical examination, temperature is 37.2 °C (99.0 °F), blood pressure is 110/66 mm Hg, and...
Source: Kevin, M.D. - Medical Weblog - December 9, 2017 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Gastroenterology OB/GYN Source Type: blogs

MKSAP: 29-year-old man with ulcerative colitis
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 29-year-old man is evaluated during a routine examination. His medical history is significant for ulcerative colitis involving the entire colon, which was diagnosed 4 years ago. His symptoms responded to therapy with mesalamine and have remained in remission on this medication. His family history is significant for a maternal uncle who died of colon cancer at the age of 50 years. Physical examination is unremarkable. Serum alkaline phosphatase, alanine aminotransferase, and aspartate aminotransferase levels ar...
Source: Kevin, M.D. - Medical Weblog - January 7, 2017 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions GI Source Type: blogs

Stephen’s return from the medical quagmire
Stephen shared his 60-day Wheat Belly experience: “Started Wheat Belly 60 days ago after a major health crisis. I found out I had type 2 diabetes 2 and very bad cholesterol. My numbers 60 days ago were: cholesterol 189, triglycerides 475, LDL could not be measured as it was so bad, HDL was 32. Two weeks ago: 20 pound weight loss, wearing a 15.5-inch neck size shirt compared to an 18. Triglycerides 79, LDL 25, HDL 40, cholesterol 81. “I was first told on January 24, 2016 that my glucose level was 157. Forty five days later, my average glucose was 107 when measured by my diabetes counselor by downloading the data...
Source: Wheat Belly Blog - April 7, 2016 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Success Stories cholesterol diabetes gluten grains HDL statins triglycerides Weight Loss Source Type: blogs

A drug to treat a drug to treat a drug . . .
Stacy shared her story of wheat- and grain-free success after experiencing the all-too-common disaster called modern healthcare. “I had been having gastrointestinal problems off and on for quite a while (a year or so). I would have days where I could barely function. Since I am a middle-aged woman, I kept thinking it was a combination of hormonal issues and ‘something I ate’–turns out it was! On June 22nd, everything came to a head and I was absolutely miserable. Long story short, the EGD showed I had gastritis and my scans and colonoscopy confirmed I had ileitis. The gastroenterologist put me on N...
Source: Wheat Belly Blog - October 3, 2015 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle colitis gastritis gluten grains ileitis Source Type: blogs

Shire Settles Claims of Deceptive Marketing of Multiple Drugs for $56.8 Million, No Individual Held Responsible
Here we go again.  A big drug company has settled claims of deceptive marketing, yet no individual was held accountable.  The most extensive coverage came from the Philadelphia Inquirer, presumably since the announcement came from the local US Attorney.The basics were:Shire Pharmaceuticals L.L.C. will pay $56.5 million to settle allegations that it inappropriately promoted the sale of ADHD medicine, among other drugs, the U.S. Attorney's Office in Philadelphia said Wednesday.Shire is registered in the Channel Islands and headquartered in Dublin, but operates from the United States....As is usual in such cases,...
Source: Health Care Renewal - September 26, 2014 Category: Health Management Tags: corporate integrity agreement deception legal settlements marketing Shire US Department of Justice Source Type: blogs

Seeing is believing
Read this wonderful tale of freedom from the bonds of wheat’s grip over appetite, as well as relief from decades of Crohn’s disease. I am 42 years old and I work as a flight attendant. I eat an excellent diet, I exercise regularly and I live a very active lifestyle. I run approximately 30 km [about 18 miles] a week. I am 5’7” and weighed 160.2 lbs. I have been tracking my calories using the “MyFitnessPal” app on my iPhone for over a year and I have not been able to lose the 15-20 lbs that has crept up on me in the last 10 years. I carry the extra weight from the bottom of my rib cage to my mid-thighs....
Source: Wheat Belly Blog - June 30, 2013 Category: Cardiology Authors: Dr. Davis Tags: Crohns disease Wheat-elimination success stories Source Type: blogs

Hot flashes no more!
Deb posted this comment in response to the Smarter, Faster, Better post describing the transformations in her brother’s life and her own health minus wheat: After watching my 52-year-old brother drop 53 pounds in 6 months, I knew he was onto something BIG! For years he had experienced severe digestive issues, was turning into a recluse, he complained constantly about aches and pains, and he was depressed. A friend turned him onto Wheat Belly and it changed his life. Thank you for giving me my brother back! After eliminating wheat, he no longer has any digestive-colitis issues, his depression is gone (without medicati...
Source: Wheat Belly Blog - June 26, 2013 Category: Cardiology Authors: Dr. Davis Tags: Wheat-elimination success stories Source Type: blogs

Shire to pay $57.5 million over marketing of five drugs
David Sell, Inquirer Staff Writer Posted: Saturday, February 2, 2013, 3:01 AM Shire P.L.C. said Friday that it would pay $57.5 million as part of a tentative agreement with the Justice Department to settle an investigation related to marketing practices of five drugs. A spokeswoman for the U.S. Attorney's Office in Philadelphia, which handled the investigation, declined comment. Shire has its headquarters in Ireland, but its main office is in Wayne, Delaware County. Shire said the drugs involved are Adderall XR, Vyvanse, Daytrana, Lialda, and Pentasa. Some companies will announce such tentative agreements because the...
Source: PharmaGossip - February 2, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs

MKSAP: 38-year-old man with ulcerative colitis
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.A 38-year-old man is evaluated during a routine examination. He was diagnosed with ulcerative colitis 10 years ago and is currently asymptomatic. His last colonoscopy, performed at the time of diagnosis, showed mildly active extensive colitis extending to the hepatic flexure. There is no family history of colon cancer or colon polyps. His only medication is mesalamine.On physical examination, vital signs are normal. Abdominal examination is normal. Laboratory studies, including a complete blood count, liver chemis...
Source: Kevin, M.D. - Medical Weblog - January 26, 2013 Category: Family Physicians Tags: Conditions GI Source Type: blogs