Longitudinal changes in brain-derived neurotrophic factor (BDNF) but not cytokines contribute to hippocampal recovery in anorexia nervosa above increases in body mass index
CONCLUSIONS: These findings suggest that increases in BDNF may contribute to global hippocampal recovery over and above increases in BMI during renourishment. Investigations into treatments targeted toward increasing BDNF in AN may be warranted.PMID:38450444 | DOI:10.1017/S0033291724000394 (Source: Psychological Medicine)
Source: Psychological Medicine - March 7, 2024 Category: Psychiatry Authors: Johanna Louise Keeler Klaas Bahnsen Marie-Louis Wronski Fabio Bernardoni Friederike Tam Dominic Arold Joseph A King Theresa Kolb David M Poitz Veit Roessner Janet Treasure Hubertus Himmerich Stefan Ehrlich Source Type: research
The processing intermediate of human amylin, pro-amylin(1-48), has in vivo and in vitro bioactivity
Biophys Chem. 2024 Feb 15;308:107201. doi: 10.1016/j.bpc.2024.107201. Online ahead of print.ABSTRACTAmylin is released by pancreatic beta-cells in response to a meal and its major soluble mature form (37 amino acid-peptide) produces its biological effects by activating amylin receptors. Amylin is derived from larger propeptides that are processed within the synthesizing beta-cell. There are suggestions that a partially processed form, pro-amylin(1-48) is also secreted. We tested the hypothesis that pro-amylin(1-48) has biological activity and that human pro-amylin(1-48) may also form toxic pre-amyloid species. Amyloid form...
Source: Biophysical Chemistry - March 7, 2024 Category: Chemistry Authors: Giulia Mazzini Christelle Le Foll Christina N Boyle Michael L Garelja Alexander Zhyvoloup Matthew E T Miller Debbie L Hay Daniel P Raleigh Thomas A Lutz Source Type: research
Development of an inpatient protocol for adolescents with avoidant/restrictive food intake disorder: a case study
CONCLUSION: Further evaluation would help identify how well this protocol meets the needs of different adolescents with ARFID.PMID:38449721 | PMC:PMC10914147 (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)
Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry - March 7, 2024 Category: Psychiatry Authors: Danielle Pogos Melissa Whitelaw Claire Burton Susan M Sawyer Source Type: research
Longitudinal changes in brain-derived neurotrophic factor (BDNF) but not cytokines contribute to hippocampal recovery in anorexia nervosa above increases in body mass index
CONCLUSIONS: These findings suggest that increases in BDNF may contribute to global hippocampal recovery over and above increases in BMI during renourishment. Investigations into treatments targeted toward increasing BDNF in AN may be warranted.PMID:38450444 | DOI:10.1017/S0033291724000394 (Source: Psychological Medicine)
Source: Psychological Medicine - March 7, 2024 Category: Psychiatry Authors: Johanna Louise Keeler Klaas Bahnsen Marie-Louis Wronski Fabio Bernardoni Friederike Tam Dominic Arold Joseph A King Theresa Kolb David M Poitz Veit Roessner Janet Treasure Hubertus Himmerich Stefan Ehrlich Source Type: research
The processing intermediate of human amylin, pro-amylin(1-48), has in vivo and in vitro bioactivity
Biophys Chem. 2024 Feb 15;308:107201. doi: 10.1016/j.bpc.2024.107201. Online ahead of print.ABSTRACTAmylin is released by pancreatic beta-cells in response to a meal and its major soluble mature form (37 amino acid-peptide) produces its biological effects by activating amylin receptors. Amylin is derived from larger propeptides that are processed within the synthesizing beta-cell. There are suggestions that a partially processed form, pro-amylin(1-48) is also secreted. We tested the hypothesis that pro-amylin(1-48) has biological activity and that human pro-amylin(1-48) may also form toxic pre-amyloid species. Amyloid form...
Source: Biophysical Chemistry - March 7, 2024 Category: Chemistry Authors: Giulia Mazzini Christelle Le Foll Christina N Boyle Michael L Garelja Alexander Zhyvoloup Matthew E T Miller Debbie L Hay Daniel P Raleigh Thomas A Lutz Source Type: research
Longitudinal changes in brain-derived neurotrophic factor (BDNF) but not cytokines contribute to hippocampal recovery in anorexia nervosa above increases in body mass index
CONCLUSIONS: These findings suggest that increases in BDNF may contribute to global hippocampal recovery over and above increases in BMI during renourishment. Investigations into treatments targeted toward increasing BDNF in AN may be warranted.PMID:38450444 | DOI:10.1017/S0033291724000394 (Source: Psychological Medicine)
Source: Psychological Medicine - March 7, 2024 Category: Psychiatry Authors: Johanna Louise Keeler Klaas Bahnsen Marie-Louis Wronski Fabio Bernardoni Friederike Tam Dominic Arold Joseph A King Theresa Kolb David M Poitz Veit Roessner Janet Treasure Hubertus Himmerich Stefan Ehrlich Source Type: research
Development of an inpatient protocol for adolescents with avoidant/restrictive food intake disorder: a case study
CONCLUSION: Further evaluation would help identify how well this protocol meets the needs of different adolescents with ARFID.PMID:38449721 | PMC:PMC10914147 (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)
Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry - March 7, 2024 Category: Psychiatry Authors: Danielle Pogos Melissa Whitelaw Claire Burton Susan M Sawyer Source Type: research
The processing intermediate of human amylin, pro-amylin(1-48), has in vivo and in vitro bioactivity
Biophys Chem. 2024 Feb 15;308:107201. doi: 10.1016/j.bpc.2024.107201. Online ahead of print.ABSTRACTAmylin is released by pancreatic beta-cells in response to a meal and its major soluble mature form (37 amino acid-peptide) produces its biological effects by activating amylin receptors. Amylin is derived from larger propeptides that are processed within the synthesizing beta-cell. There are suggestions that a partially processed form, pro-amylin(1-48) is also secreted. We tested the hypothesis that pro-amylin(1-48) has biological activity and that human pro-amylin(1-48) may also form toxic pre-amyloid species. Amyloid form...
Source: Biophysical Chemistry - March 7, 2024 Category: Chemistry Authors: Giulia Mazzini Christelle Le Foll Christina N Boyle Michael L Garelja Alexander Zhyvoloup Matthew E T Miller Debbie L Hay Daniel P Raleigh Thomas A Lutz Source Type: research
Development of an inpatient protocol for adolescents with avoidant/restrictive food intake disorder: a case study
CONCLUSION: Further evaluation would help identify how well this protocol meets the needs of different adolescents with ARFID.PMID:38449721 | PMC:PMC10914147 (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)
Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry - March 7, 2024 Category: Psychiatry Authors: Danielle Pogos Melissa Whitelaw Claire Burton Susan M Sawyer Source Type: research
Longitudinal changes in brain-derived neurotrophic factor (BDNF) but not cytokines contribute to hippocampal recovery in anorexia nervosa above increases in body mass index
CONCLUSIONS: These findings suggest that increases in BDNF may contribute to global hippocampal recovery over and above increases in BMI during renourishment. Investigations into treatments targeted toward increasing BDNF in AN may be warranted.PMID:38450444 | DOI:10.1017/S0033291724000394 (Source: Psychological Medicine)
Source: Psychological Medicine - March 7, 2024 Category: Psychiatry Authors: Johanna Louise Keeler Klaas Bahnsen Marie-Louis Wronski Fabio Bernardoni Friederike Tam Dominic Arold Joseph A King Theresa Kolb David M Poitz Veit Roessner Janet Treasure Hubertus Himmerich Stefan Ehrlich Source Type: research
The processing intermediate of human amylin, pro-amylin(1-48), has in vivo and in vitro bioactivity
Biophys Chem. 2024 Feb 15;308:107201. doi: 10.1016/j.bpc.2024.107201. Online ahead of print.ABSTRACTAmylin is released by pancreatic beta-cells in response to a meal and its major soluble mature form (37 amino acid-peptide) produces its biological effects by activating amylin receptors. Amylin is derived from larger propeptides that are processed within the synthesizing beta-cell. There are suggestions that a partially processed form, pro-amylin(1-48) is also secreted. We tested the hypothesis that pro-amylin(1-48) has biological activity and that human pro-amylin(1-48) may also form toxic pre-amyloid species. Amyloid form...
Source: Biophysical Chemistry - March 7, 2024 Category: Chemistry Authors: Giulia Mazzini Christelle Le Foll Christina N Boyle Michael L Garelja Alexander Zhyvoloup Matthew E T Miller Debbie L Hay Daniel P Raleigh Thomas A Lutz Source Type: research
Development of an inpatient protocol for adolescents with avoidant/restrictive food intake disorder: a case study
CONCLUSION: Further evaluation would help identify how well this protocol meets the needs of different adolescents with ARFID.PMID:38449721 | PMC:PMC10914147 (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)
Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry - March 7, 2024 Category: Psychiatry Authors: Danielle Pogos Melissa Whitelaw Claire Burton Susan M Sawyer Source Type: research
The processing intermediate of human amylin, pro-amylin(1-48), has in vivo and in vitro bioactivity
Biophys Chem. 2024 Feb 15;308:107201. doi: 10.1016/j.bpc.2024.107201. Online ahead of print.ABSTRACTAmylin is released by pancreatic beta-cells in response to a meal and its major soluble mature form (37 amino acid-peptide) produces its biological effects by activating amylin receptors. Amylin is derived from larger propeptides that are processed within the synthesizing beta-cell. There are suggestions that a partially processed form, pro-amylin(1-48) is also secreted. We tested the hypothesis that pro-amylin(1-48) has biological activity and that human pro-amylin(1-48) may also form toxic pre-amyloid species. Amyloid form...
Source: Biophysical Chemistry - March 7, 2024 Category: Chemistry Authors: Giulia Mazzini Christelle Le Foll Christina N Boyle Michael L Garelja Alexander Zhyvoloup Matthew E T Miller Debbie L Hay Daniel P Raleigh Thomas A Lutz Source Type: research
Development of an inpatient protocol for adolescents with avoidant/restrictive food intake disorder: a case study
CONCLUSION: Further evaluation would help identify how well this protocol meets the needs of different adolescents with ARFID.PMID:38449721 | PMC:PMC10914147 (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)
Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry - March 7, 2024 Category: Psychiatry Authors: Danielle Pogos Melissa Whitelaw Claire Burton Susan M Sawyer Source Type: research
Development of an inpatient protocol for adolescents with avoidant/restrictive food intake disorder: a case study
CONCLUSION: Further evaluation would help identify how well this protocol meets the needs of different adolescents with ARFID.PMID:38449721 | PMC:PMC10914147 (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)
Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry - March 7, 2024 Category: Psychiatry Authors: Danielle Pogos Melissa Whitelaw Claire Burton Susan M Sawyer Source Type: research
