Body weight variation is not an independent factor in the determination of functional hypothalamic amenorrhea in anorexia nervosa
ConclusionsFHA does not correlate strictly with body weight variations in AN patients, indicating a multifactorial origin, likely including an individual predisposition. Higher FT3 levels identify patients who continue having menses at extremely low BMI. AN patients with persistent FHA constitute a subgroup in whom estroprogestins should be considered after significant weight recovery to prevent prolonged tissue hypoestrogenism. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - March 27, 2024 Category: Endocrinology Source Type: research

Eating Disorder Symptomatology Among Young Adult Cigarette and E-Cigarette Users
Discussion: Our findings suggest young adults with ED symptomatology were more likely to be users of e-cigarettes exclusively or dual users. It will be necessary to examine how these associations manifest using longitudinal and clinical populations in future research.PMID:38533542 | DOI:10.1080/10826084.2024.2330910 (Source: Substance Use and Misuse)
Source: Substance Use and Misuse - March 27, 2024 Category: Addiction Authors: Caitlin E Smith Tyler B Mason Afton Kechter John R Monterosso Alayna P Tackett Source Type: research

From early relational experiences to non-suicidal self-injury in anorexia and bulimia nervosa: a structural equation model unraveling the role of impairments in interoception
CONCLUSIONS: The proposed model provided a novel explanation of the occurrence of NSSIs in patients with AN and BN by accounting for the significance of interoception.LEVEL OF EVIDENCE: Level V-Cross-sectional observational study.PMID:38528258 | DOI:10.1007/s40519-024-01651-x (Source: Eating and weight disorders : EWD)
Source: Eating and weight disorders : EWD - March 26, 2024 Category: Eating Disorders & Weight Management Authors: Lorenzo Lucherini Angeletti Emanuele Cassioli Livio Tarchi Cristiano Dani Marco Faldi Rachele Martini Valdo Ricca Giovanni Castellini Eleonora Rossi Source Type: research

Clinical implication of megestrol acetate in metastatic gastric cancer: a big data analysis from Health Insurance Review and Assessment (HIRA) database
ConclusionMA is commonly prescribed for metastatic gastric cancer, especially in elderly patients and those undergoing palliative chemotherapy, without significantly affecting survival or VTE risk. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 26, 2024 Category: Cancer & Oncology Source Type: research

Anorexia caused by giant right atrial aneurysm: A case report
Asian J Surg. 2024 Mar 23:S1015-9584(24)00565-7. doi: 10.1016/j.asjsur.2024.03.136. Online ahead of print.NO ABSTRACTPMID:38522987 | DOI:10.1016/j.asjsur.2024.03.136 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - March 24, 2024 Category: Surgery Authors: Jun Xiang Ling He Yinglong Lai Source Type: research

Anorexia caused by giant right atrial aneurysm: A case report
Asian J Surg. 2024 Mar 23:S1015-9584(24)00565-7. doi: 10.1016/j.asjsur.2024.03.136. Online ahead of print.NO ABSTRACTPMID:38522987 | DOI:10.1016/j.asjsur.2024.03.136 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - March 24, 2024 Category: Surgery Authors: Jun Xiang Ling He Yinglong Lai Source Type: research

Anorexia caused by giant right atrial aneurysm: A case report
Asian J Surg. 2024 Mar 23:S1015-9584(24)00565-7. doi: 10.1016/j.asjsur.2024.03.136. Online ahead of print.NO ABSTRACTPMID:38522987 | DOI:10.1016/j.asjsur.2024.03.136 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - March 24, 2024 Category: Surgery Authors: Jun Xiang Ling He Yinglong Lai Source Type: research

Efficacy and safety of PARP inhibitors combined with antiangiogenic agents in the maintenance treatment of ovarian cancer: a systematic review and meta-analysis with trial sequential analysis of randomized controlled trials
Conclusion: Our study demonstrated the PFS benefit of combination therapy with PARP inhibitors and antiangiogenic agents in patients with OC. The OS result need to be updated after the original trial data is mature. Clinicians should be vigilant of AEs when administering the combination therapy in clinical practice.Systematic Review Registration:https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42023494482. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - March 22, 2024 Category: Drugs & Pharmacology Source Type: research

Efficacy of probiotic supplements in improving the symptoms of psychosis, anxiety, insomnia, and anorexia due to amphetamine and methamphetamine use: a randomized clinical trial
ConclusionsThe use of probiotics was associated with improved sleep quality, increased appetite, and increased body mass index in patients with chronic methamphetamine use. Conducting more definitive clinical trials with larger sample sizes and longer-term follow-up of cases is recommended. (Source: Psychopharmacology)
Source: Psychopharmacology - March 21, 2024 Category: Psychiatry Source Type: research

UArizona scientists pinpoint anorexia's neurologic origins
This study suggests two important insights to treat anorexia, " Cai said. " One is that we need to target multiple brain regions to develop therapies. We also need to treat multiple conditions. For example, maybe one drug will target nausea and another drug target will target inflammation, and you have to combine them, like a cocktail therapy, to have better therapeutic effects. "The team relied on mice models for their research." There ' s no animal model that can mimic human disease completely, but this is as close as we can get, " Cai said. " For example, there are multiple common features, including a warped body image...
Source: The University of Arizona: Health - March 20, 2024 Category: Universities & Medical Training Authors: mikaylamace Source Type: research

Families tackling adolescent anorexia nervosa: family wellbeing in family-based treatment or other interventions. A scoping review
CONCLUSION: The available research suggests no difference between intervention types regarding impact on family wellbeing. Approximately half of the studies find improvements in family wellbeing in both treatment with and without parent-led refeeding, while the same proportion find neither improvement nor deterioration. As parents play a pivotal role in FBT, there is a need for good quality studies to elucidate the impact of FBT on family wellbeing. Level of evidence Level V: Opinions of authorities, based on descriptive studies, narrative reviews, clinical experience, or reports of expert committees.PMID:38504003 | DOI:10...
Source: Eating and weight disorders : EWD - March 20, 2024 Category: Eating Disorders & Weight Management Authors: Signe Holm Pedersen Dorthe Andersen Waage Nadia Micali Mette Bentz Source Type: research

Associations between nutritional intake, stress and hunger biomarkers, and anxiety and depression during the treatment of anorexia nervosa in adolescents and young adults
Eat Behav. 2023 Dec;51:101822. doi: 10.1016/j.eatbeh.2023.101822. Epub 2023 Oct 26.ABSTRACTAdolescents and young adults (AYA) with anorexia nervosa (AN) frequently have co-occurring anxiety and depression, which can negatively impact prognosis. To inform treatment of co-occurring anxiety and depression, we assessed the association of nutritional intake and hunger/stress hormones on anxiety and depression using a six-month longitudinal study of 50 AYA females receiving care for AN. At baseline and six months, we measured anxiety (Spielberger State/Trait Anxiety Inventory [STAI]), depression (Beck Depression Inventory [BDI])...
Source: Eating Behaviors - March 20, 2024 Category: Eating Disorders & Weight Management Authors: Jessica A Lin Catherine Stamoulis Amy D DiVasta Source Type: research

Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi
The objective of this report was to describe such a case.METHODS: An 82-year-old woman with advanced cervical cancer was admitted for palliative care because of progressive disease. One month after admission, she developed myoclonus on the left side, difficulty speaking, slurred speech, and drooping of the left corner of the mouth, with no consciousness disturbance. She also developed nausea and complained of decreased dietary intake for more than 2 weeks.RESULTS: The patient's thiamine level, which had been measured 2 weeks earlier, was 27 ng/ml, which was below the normal range, and 100 mg of thiamine was administered in...
Source: Palliative and Supportive Care - March 20, 2024 Category: Palliative Care Authors: Eriko Hayashi Tetsuya Matuura Junko Takano Kaori Morofushi Kaori Toriizuka Hideki Onishi Source Type: research

Families tackling adolescent anorexia nervosa: family wellbeing in family-based treatment or other interventions. A scoping review
CONCLUSION: The available research suggests no difference between intervention types regarding impact on family wellbeing. Approximately half of the studies find improvements in family wellbeing in both treatment with and without parent-led refeeding, while the same proportion find neither improvement nor deterioration. As parents play a pivotal role in FBT, there is a need for good quality studies to elucidate the impact of FBT on family wellbeing. Level of evidence Level V: Opinions of authorities, based on descriptive studies, narrative reviews, clinical experience, or reports of expert committees.PMID:38504003 | DOI:10...
Source: Eating and weight disorders : EWD - March 20, 2024 Category: Eating Disorders & Weight Management Authors: Signe Holm Pedersen Dorthe Andersen Waage Nadia Micali Mette Bentz Source Type: research

Associations between nutritional intake, stress and hunger biomarkers, and anxiety and depression during the treatment of anorexia nervosa in adolescents and young adults
Eat Behav. 2023 Dec;51:101822. doi: 10.1016/j.eatbeh.2023.101822. Epub 2023 Oct 26.ABSTRACTAdolescents and young adults (AYA) with anorexia nervosa (AN) frequently have co-occurring anxiety and depression, which can negatively impact prognosis. To inform treatment of co-occurring anxiety and depression, we assessed the association of nutritional intake and hunger/stress hormones on anxiety and depression using a six-month longitudinal study of 50 AYA females receiving care for AN. At baseline and six months, we measured anxiety (Spielberger State/Trait Anxiety Inventory [STAI]), depression (Beck Depression Inventory [BDI])...
Source: Eating Behaviors - March 20, 2024 Category: Eating Disorders & Weight Management Authors: Jessica A Lin Catherine Stamoulis Amy D DiVasta Source Type: research