Neural stem cells derived from primitive mesenchymal stem cells reversed disease symptoms and promoted neurogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis

CONCLUSIONS: NSC transplantation reversed the disease process by inducing an anti-inflammatory response and promoting myelination, neuroprotection, and neurogenesis in EAE disease animals. These promising results provide a basis for clinical studies to treat MS using NSCs derived from primitive MSCs.PMID:34503569 | DOI:10.1186/s13287-021-02563-8

Source: Cell Research - September 10, 2021 Category: Cytology Authors: Christina Brown Christina McKee Sophia Halassy Suleiman Kojan Doug L Feinstein G Rasul Chaudhry Source Type: research