P –106 The evaluation of dietary score representing the overall effect of men’s diet to semen quality on couple’s fertility

AbstractStudy questionIs men ’s diet associated with assisted reproductive technology (ART) outcomes?Summary answerAn empirical dietary score representing the overall effect of men ’s diet on semen quality was unrelated to ART outcomes.What is known alreadyMultiple studies have related various aspects of men ’s diet to semen quality. Generally, healthier foods, such as fish, vegetables, and fruits, have been related to better semen quality, whereas unhealthy foods, like processed and red meats, have had the opposite relationship. Nevertheless, while bulk semen parameters are important biomarkers of ma le fertility and a diagnostic cornerstone for male factor infertility, they are imperfect predictors of a couple’s fertility.Study design, size, durationCouples presenting to the Massachusetts General Hospital Fertility Center between April 2007 and April 2018 were invited to participate in the Environment and Reproductive Health (EARTH) study, a prospective cohort study. Men ’s diet was assessed with a previously validated food frequency questionnaire. A dietary score reflecting the overall relation of men’s food intake with semen quality parameters was empirically derived using reduced rank regression (RRR). The resulting dietary score was related to ART outcomes.Participants/materials, setting, methodsWe used information from 349 men (908 semen samples) to derive the empirical diet pattern and data from 231 couples (407 ART cycles). The primary outcome was the pro...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research