Frequency, clinical characteristics and outcome of adults with acute lymphoblastic leukemia and COVID 19 infection in the first vs. second pandemic wave in Spain

SARS-CoV-2 (COVID-19) infection has a negative impact on the outcomes of patients with cancer, with mortality rates over 20%.1-3 This is especially important in adults with hematologic neoplasias and in those submitted to allogeneic hematopoietic stem cell transplant (HSCT), in whom the death rate is over 30%4-8 compared to 4% in children.4 Patients with active disease and those receiving intensive chemotherapy or immunotherapy are especially vulnerable. Apart from the cancer itself other factors such as advanced age, poor general status and neutropenia contribute to this high mortality rate.

Source: Clinical Lymphoma, Myeloma and Leukemia - July 18, 2021 Category: Hematology Authors: Josep-Maria Ribera, Mireia Morgades, Rosa Coll, Pere Barba, Jose-Luis L ópez-Lorenzo, Pau Montesinos, María-Angeles Foncillas, Mónica Cabrero, Ignacio Gómez-Centurión, María-Dolores Morales, María-Rosario Varela, Pilar Herrera, Irene García-Cadena Source Type: research