The TIRS trial: protocol for a cluster randomized controlled trial assessing the efficacy of preventive targeted indoor residual spraying to reduce Aedes -borne viral illnesses in Merida, Mexico

DiscussionThe findings from this study will provide robust epidemiological evidence of the efficacy of TIRS in reducing ABV illness and infection. If efficacious, TIRS could drive a paradigm shift inAedes control by consideringAe. aegypti behavior to guide residual insecticide applications and changing deployment to preemptive control (rather than in response to symptomatic cases), two major enhancements to existing practice.Trial registrationClinicalTrials.govNCT04343521. Registered on 13 April 2020. The protocol also complies with the WHO International Clinical Trials Registry Platform (ICTRP) (Additional file 1).Primary sponsorNational Institutes of Health, National Institute of Allergy and Infectious Diseases (NIH/NIAID).
Source: Trials - Category: Research Source Type: clinical trials