MicroRNAs of bone marrow mesenchymal stem cell-derived exosomes regulate acute myeloid leukemia cell proliferation and apoptosis.

CONCLUSIONS: BMSCs-derived exosomes suppress cell proliferation and cycle progression and promote cell apoptosis in KG-1a cells, likely acting through hsa-miR-124-5p. Our study establishes a basis for a BMSCs-derived exosomes-based AML treatment.
PMID: 33021767 [PubMed - as supplied by publisher]

Source: Chinese Medical Journal - October 5, 2020 Category: General Medicine Authors: Xu YC, Lin YS, Zhang L, Lu Y, Sun YL, Fang ZG, Li ZY, Fan RF Tags: Chin Med J (Engl) Source Type: research